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Invitrogen
MID2 Polyclonal Antibody
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Product Details
PA5-18129
Product Specifications
Species Reactivity
Human
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide sequence (QESPYVSGMKTCH) corresponding to the C-terminus amino acids of MID2 (aa 723-735).
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Ammonium sulfate precipitation
Storage buffer
TBS, pH 7.3, with 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_10980697
Product Specific Information
This antibody is expected to recognize both human isoforms of this protein.
It is predicted to react with bovine, canine and porcine based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 4,000.
Target Information
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to microtubular structures in the cytoplasm. Alternate splicing of this gene results in two transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ37715; FLJ41813; midin 2; Midin-2; Midline defect 2; Midline-2; Probable E3 ubiquitin-protein ligase MID2; RING finger protein 60; RING-type E3 ubiquitin transferase MID2; RP6-191P20.2; tripartite motif protein 1; Tripartite motif-containing protein 1
Gene Aliases: FXY2; MID2; MRX101; RNF60; TRIM1
UniProt ID: (Human) Q9UJV3
Entrez Gene ID: (Human) 11043
positive regulation of autophagy
protein ubiquitination
negative regulation of viral transcription
protein localization to microtubule
positive regulation of I-kappaB kinase/NF-kappaB signaling
innate immune response
negative regulation of viral entry into host cell
positive regulation of sequence-specific DNA binding transcription factor activity
positive regulation of NF-kappaB transcription factor activity
negative regulation of viral release from host cell
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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