Proteintech

MIP-3 alpha Polyclonal Antibody

MIP-3 alpha Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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MIP-3 alpha Antibody (26527-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using 26527-1-AP (MIP-3α Antibody) at dilution of 1:200 (under 40x lens). heat mediated antigen retrieved with Tris-EDTA buffer (pH 9).

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Product Details

26527-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

View 2 publications 2 publications

Immunohistochemistry (IHC)

View 3 publications 3 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

Immunocytochemistry (ICC/IF)

View 2 publications 2 publications

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

MIP-3alpha Fusion Protein Ag24069 (26-95 aa encoded by BC020698)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.3 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: ASNFDCCLG YTDRILHPKF IVGFTRQLAN EGCDINAIIF HTKKKLSVCA NPKQTWVKYI VRLLSKKVKN M (26-95 aa encoded by BC020698)

Target Information

Macrophage Inflammatory Protein-3 alpha (MIP-3alpha), also called CCL20, is expressed in the liver, lungs, lymph nodes and peripheral blood lymphocytes. MIP-3alpha is strongly up regulated by inflammatory signals, and down regulated by the anti-inflammatory cytokine IL-10. MIP3alpha signals through the G protein-coupled receptor, CCR6, and acts as a chemoattractant to lymphocytes and dendritic cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

The secretion of sIgA and dendritic cells activation in the intestinal of cyclophosphamide-induced immunosuppressed mice are regulated by Alhagi honey polysaccharides.

Phytomedicine : international journal of phytotherapy and phytopharmacology

Cai G,Yang Y,Gu P,Li K,Adelijiang W,Zhu T,Liu Z,Wang D

Mon Aug 01 00:00:00 UTC 2022

Fusobacterium nucleatum promotes colorectal cancer metastasis through miR-1322/CCL20 axis and M2 polarization.

Gut microbes

Xu C,Fan L,Lin Y,Shen W,Qi Y,Zhang Y,Chen Z,Wang L,Long Y,Hou T,Si J,Chen S

Mon Jan 24 00:00:00 UTC 2022

Overexpression of B7-H4 promotes renal cell carcinoma progression by recruiting tumor-associated neutrophils via upregulation of CXCL8.

Oncology letters

Li A,Zhang N,Zhao Z,Chen Y,Zhang L

Sat Aug 01 00:00:00 UTC 2020

EZH2-Inhibited MicroRNA-454-3p Promotes M2 Macrophage Polarization in Glioma.

Frontiers in cell and developmental biology

Qi B,Yang C,Zhu Z,Chen H

Tue Dec 29 00:00:00 UTC 2020

Tacrolimus Inhibits TNF-α/IL-17A-Produced pro-Inflammatory Effect on Human Keratinocytes by Regulating IκBζ.

Inflammation

Hu Y,Guo J,Yin L,Tu J,Yin Z

Wed Apr 01 00:00:00 UTC 2020

DEPDC1 drives hepatocellular carcinoma cell proliferation, invasion and angiogenesis by regulating the CCL20/CCR6 signaling pathway.

Oncology reports

Guo W,Li H,Liu H,Ma X,Yang S,Wang Z

Sun Sep 01 00:00:00 UTC 2019

Comprehensive transcriptome analysis based on RNA sequencing identifies critical genes for lipopolysaccharide-induced epididymitis in a rat model.

Asian journal of andrology

Song X,Lin NH,Wang YL,Chen B,Wang HX,Hu K

Mon Aug 17 00:00:00 UTC 2020

Bioinformatics

Protein Aliases: beta chemokine exodus-1; Beta-chemokine exodus-1; C-C motif chemokine 20; CC chemokine LARC; chemokine (C-C motif) ligand 20; Liver and activation-regulated chemokine; M-MIP-3-alpha; Macrophage inflammatory protein 3 alpha; MIP 3 a; MIP 3 α; MIP 3alpha; MIP 3α; MIP-3-alpha; MIP3 a; MIP3 alpha; MIP3 α; small inducible cytokine subfamily A (Cys-Cys), member 20; Small-inducible cytokine A20

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Gene Aliases: CCL20; CKb4; Exodus; LARC; MIP-3-alpha; MIP-3a; MIP3A; SCYA20; ST38

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UniProt ID: (Human) P78556

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Entrez Gene ID: (Human) 6364

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Function(s)

protein binding chemokine activity CCR6 chemokine receptor binding CCR chemokine receptor binding

Process(es)

monocyte chemotaxis chemotaxis inflammatory response immune response signal transduction G-protein coupled receptor signaling pathway cell-cell signaling neutrophil chemotaxis calcium-mediated signaling using intracellular calcium source wound healing defense response to bacterium positive regulation of GTPase activity lymphocyte chemotaxis positive regulation of interleukin-1 alpha biosynthetic process positive regulation of nitric-oxide synthase biosynthetic process cell chemotaxis chemokine-mediated signaling pathway positive regulation of ERK1 and ERK2 cascade cellular response to lipopolysaccharide cellular response to lipoteichoic acid cellular response to interferon-gamma cellular response to interleukin-1 cellular response to tumor necrosis factor T cell migration thymocyte migration positive regulation of T cell migration

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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MIP-3 alpha Polyclonal Antibody

MIP-3 alpha Antibody (26527-1-AP) in IHC (P)

Product Details

26527-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Species Reactivity

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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