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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • MKKS Antibodies

          Invitrogen

          MKKS Polyclonal Antibody

          View all (7) MKKS antibodies

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          Datasheet
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          Datasheet
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          Cite MKKS Polyclonal Antibody

          • Antibody Testing Data (5)
          MKKS Antibody in Immunohistochemistry (IHC)
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          MKKS Antibody in Immunohistochemistry (IHC)
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          FIGURE: 1 / 5

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          MKKS Antibody (PA5-59416) in IHC

          Immunohistochemical staining of MKKS in human colon using a MKKS Polyclonal Antibody (Product # PA5-59416) shows strong cytoplasmic positivity in glandular cells. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          MKKS Antibody in Immunohistochemistry (IHC)
          MKKS Antibody in Immunohistochemistry (IHC)
          MKKS Antibody in Immunohistochemistry (IHC)
          MKKS Antibody in Immunohistochemistry (IHC)
          MKKS Antibody in Immunohistochemistry (IHC)

          Product Details

          PA5-59416

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          0.04-0.4 µg/mL
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:20-1:50
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein corresponding to Human MKKS. Recombinant protein control fragment (Product #RP-99410).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.05 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2643987

          Product Specific Information

          Immunogen sequence: ALESVVGSLE HDGGEILTDM KYGHLWSVQA DSPCVANWPD LLSQCGCGLY NSQEELNWSF LRSTRRPFVP QSCLPHEAVG SASNLTL

          Highest antigen sequence identity to the following orthologs: Mouse - 77%, Rat - 74%.

          Target Information

          Probable molecular chaperone. Assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. May play a role in protein processing in limb, cardiac and reproductive system development. May play a role in cytokinesis.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: Bardet-Biedl syndrome 6 protein; McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin; Molecular chaperone MKKS

          View more View less

          Gene Aliases: BBS6; HMCS; KMS; MKKS; MKS

          View more View less

          UniProt ID: (Human) Q9NPJ1

          View more View less

          Entrez Gene ID: (Human) 8195

          View more View less

          Function(s)
          RNA polymerase II repressing transcription factor binding protein binding ATP binding unfolded protein binding
          Process(es)
          heart looping protein folding spermatid development determination of left/right symmetry heart development visual perception sensory perception of smell gonad development negative regulation of gene expression artery smooth muscle contraction striatum development hippocampus development cerebral cortex development negative regulation of actin filament polymerization melanosome transport negative regulation of GTPase activity nonmotile primary cilium assembly social behavior negative regulation of appetite by leptin-mediated signaling pathway positive regulation of multicellular organism growth vasodilation cilium assembly fat cell differentiation photoreceptor cell maintenance negative regulation of blood pressure intracellular transport brain morphogenesis detection of mechanical stimulus involved in sensory perception of sound chaperone-mediated protein complex assembly cartilage development regulation of stress fiber assembly pigment granule aggregation in cell center convergent extension involved in gastrulation cilium morphogenesis regulation of cilium beat frequency involved in ciliary motility face development
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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