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OriGene
MKX Monoclonal Antibody (OTI6B9), TrueMAB™
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FIGURE: 1 / 1
MKX Antibody (CF808429) in WB
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MKX (RC206923, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-MKX. (1:2. Positive lysates LY406487 (100 µg) and LC406487 (20 µg) can be purchased separately from OriGene.
Product Details
CF808429
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
OTI6B9
Immunogen
Full length human recombinant protein of human MKX produced in E.coli.
Conjugate
Form
Lyophilized
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 8% trehalose
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
Target Information
MKX is a member of an Iroquois (IRX) family-related class of 'three-amino acid loop extension' (TALE) atypical homeobox proteins characterized by 3 additional amino acids in the loop region between helix I and helix II of the homeodomain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Homeobox protein Mohawk; Iroquois family related homeodomain protein; iroquois homeobox protein-like 1; mohawk homeobox
Gene Aliases: 9430023B20Rik; C10orf48; IFRX; IRXL1; MKX; RGD1305652
UniProt ID: (Human) Q8IYA7, (Mouse) Q8BIA3
Entrez Gene ID: (Human) 283078, (Mouse) 210719, (Rat) 291228
sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II transcription factor binding
DNA binding
protein binding
negative regulation of transcription from RNA polymerase II promoter
tendon sheath development
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
multicellular organism development
regulation of gene expression
positive regulation of gene expression
collagen fibril organization
positive regulation of collagen biosynthetic process
tendon cell differentiation
tendon formation
negative regulation of myoblast differentiation
positive regulation of transcription from RNA polymerase II promoter
muscle organ development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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