Product References
N-acetyl-L-cysteine alleviated the oxidative stress-induced inflammation and necroptosis caused by excessive NiCl2 in primary spleen lymphocytes.
Frontiers in immunology
Zhang X,Xu L,Ma W,Shi B,Liu Q,Song Y,Fang C,Liu P,Qiao S,Cai J,Zhang Z
Tue Apr 25 00:00:00 UTC 2023
Whether the Subacute MPTP-Treated Mouse is as Suitable as a Classic Model of Parkinsonism.
Neuromolecular medicine
Qi Y,Zhang Z,Li Y,Zhao G,Huang J,Zhang Y,Xue J,Tang X
Fri Sep 01 00:00:00 UTC 2023
Identification of necroptosis-related gene TRAF5 as potential target of diagnosing atherosclerosis and assessing its stability.
BMC medical genomics
Peng Z,Wang K,Wang S,Wu R,Yao C
Sat Jun 17 00:00:00 UTC 2023
MLKL deficiency attenuated hepatocyte oxidative DNA damage by activating mitophagy to suppress macrophage cGAS-STING signaling during liver ischemia and reperfusion injury.
Cell death discovery
Xu J,Wu D,Zhou S,Hu H,Li F,Guan Z,Zhan X,Gao Y,Wang P,Rao Z
Fri Feb 10 00:00:00 UTC 2023
MLKL deficiency attenuated hepatocyte oxidative DNA damage by activating mitophagy to suppress macrophage cGAS-STING signaling during liver ischemia and reperfusion injury.
Cell death discovery
Xu J,Wu D,Zhou S,Hu H,Li F,Guan Z,Zhan X,Gao Y,Wang P,Rao Z
Fri Feb 10 00:00:00 UTC 2023
Thymol Ameliorates Aspergillus fumigatus Keratitis by Downregulating the TLR4/ MyD88/ NF-kB/ IL-1β Signal Expression and Reducing Necroptosis and Pyroptosis.
Journal of microbiology and biotechnology
Wang L,Yan H,Chen X,Han L,Liu G,Yang H,Lu D,Liu W,Che C
Sat Jan 28 00:00:00 UTC 2023
RNA-sequencing approach for exploring the protective mechanisms of dexmedetomidine on pancreatic injury in severe acute pancreatitis.
Frontiers in pharmacology
Yao J,Lan B,Ma C,Liu Y,Wu X,Feng K,Chen H,Wen Q
Wed May 31 00:00:00 UTC 2023
Physiological ischemic training improves cardiac function through the attenuation of cardiomyocyte apoptosis and the activation of the vagus nerve in chronic heart failure.
Frontiers in neuroscience
Zhu X,Wang S,Cheng Y,Gu H,Zhang X,Teng M,Zhang Y,Wang J,Hua W,Lu X
Tue Sep 17 00:00:00 UTC 2024
Sulconazole Induces PANoptosis by Triggering Oxidative Stress and Inhibiting Glycolysis to Increase Radiosensitivity in Esophageal Cancer.
Molecular & cellular proteomics : MCP
Liu LX,Heng JH,Deng DX,Zhao H,Zheng ZY,Liao LD,Lin W,Xu XE,Li EM,Xu LY
Thu Jun 01 00:00:00 UTC 2023
Polymyxin B Reduces Brain Injury in Ischemic Stroke Rat Through a Mechanism Involving Targeting ESCRT-III Machinery and RIPK1/RIPK3/MLKL Pathway.
Journal of cardiovascular translational research
Tian J,Zhang YY,Peng YW,Liu B,Zhang XJ,Hu ZY,Hu CP,Luo XJ,Peng J
Sat Oct 01 00:00:00 UTC 2022
Blue Light Induces RPE Cell Necroptosis, Which Can Be Inhibited by Minocycline.
Frontiers in medicine
Song W,Zhu R,Gao W,Xing C,Yang L
Mon May 16 00:00:00 UTC 2022
Coeloglossum viride Var. Bracteatum Extract Attenuates MPTP-Induced Neurotoxicity in vivo by Restoring BDNF-TrkB and FGF2-Akt Signaling Axis and Inhibiting RIP1-Driven Inflammation.
Frontiers in pharmacology
Lang XY,Hu Y,Bai JP,Wang J,Qin XY,Lan R
Thu May 19 00:00:00 UTC 2022
Mixed lineage kinase domain-like pseudokinase-mediated necroptosis aggravates periodontitis progression.
Journal of molecular medicine (Berlin, Germany)
Yang Y,Wang L,Zhang H,Luo L
Sat Jan 01 00:00:00 UTC 2022
A novel necroptosis-related gene index for predicting prognosis and a cold tumor immune microenvironment in stomach adenocarcinoma.
Frontiers in immunology
Khan M,Lin J,Wang B,Chen C,Huang Z,Tian Y,Yuan Y,Bu J
Mon Nov 21 00:00:00 UTC 2022
Acteoside attenuates RSV-induced lung injury by suppressing necroptosis and regulating metabolism.
Frontiers in pharmacology
Ling X,Zhou J,Jin T,Xu W,Sun X,Li W,Ding Y,Liang M,Zhu C,Zhao P,Hu C,Yuan B,Xie T,Tao J
Wed Sep 07 00:00:00 UTC 2022
Acteoside attenuates RSV-induced lung injury by suppressing necroptosis and regulating metabolism.
Frontiers in pharmacology
Ling X,Zhou J,Jin T,Xu W,Sun X,Li W,Ding Y,Liang M,Zhu C,Zhao P,Hu C,Yuan B,Xie T,Tao J
Wed Sep 07 00:00:00 UTC 2022
Acteoside attenuates RSV-induced lung injury by suppressing necroptosis and regulating metabolism.
Frontiers in pharmacology
Ling X,Zhou J,Jin T,Xu W,Sun X,Li W,Ding Y,Liang M,Zhu C,Zhao P,Hu C,Yuan B,Xie T,Tao J
Wed Sep 07 00:00:00 UTC 2022
Acteoside attenuates RSV-induced lung injury by suppressing necroptosis and regulating metabolism.
Frontiers in pharmacology
Ling X,Zhou J,Jin T,Xu W,Sun X,Li W,Ding Y,Liang M,Zhu C,Zhao P,Hu C,Yuan B,Xie T,Tao J
Wed Sep 07 00:00:00 UTC 2022
Mesenchymal Stem Cells-Derived Exosomes Ameliorate Ischemia/Reperfusion Induced Acute Kidney Injury in a Porcine Model.
Frontiers in cell and developmental biology
Huang J,Cao H,Cui B,Ma X,Gao L,Yu C,Shen F,Yang X,Liu N,Qiu A,Cai G,Zhuang S
Fri Nov 17 00:00:00 UTC 2023
Role of HMGB1 in TNF-α Combined with Z-VAD-fmk-Induced L929 Cells Necroptosis.
Biochemical genetics
Yu C,Lei Z,Li X,Huang LH,Li ZQ,Zhu HW,Han D,Huang H,Yu X
Fri Apr 01 00:00:00 UTC 2022
Salidroside alleviates cadmium-induced toxicity in mice by restoring the notch/HES-1 and RIP1-driven inflammatory signaling axis.
Inflammation research : official journal of the European Histamine Research Society ... [et al.]
Shu XM,Hu Y,Fang X,Wang J,Qin XY,Lan R
Wed Jun 01 00:00:00 UTC 2022
Tea polyphenols alleviates acetochlor-induced apoptosis and necroptosis via ROS/MAPK/NF-κB signaling in Ctenopharyngodon idellus kidney cells.
Aquatic toxicology (Amsterdam, Netherlands)
Zhao X,Shi X,Liu Q,Li X
Sun May 01 00:00:00 UTC 2022
Selenium Deficiency Induces Apoptosis and Necroptosis Through ROS/MAPK Signal in Human Uterine Smooth Muscle Cells.
Biological trace element research
Wang Y,Li X,Yao Y,Zhao X,Shi X,Cai Y
Fri Jul 01 00:00:00 UTC 2022
Self-assembled polymeric nanocarrier-mediated co-delivery of metformin and doxorubicin for melanoma therapy.
Drug delivery
Song M,Xia W,Tao Z,Zhu B,Zhang W,Liu C,Chen S
Wed Dec 01 00:00:00 UTC 2021
Self-assembled polymeric nanocarrier-mediated co-delivery of metformin and doxorubicin for melanoma therapy.
Drug delivery
Song M,Xia W,Tao Z,Zhu B,Zhang W,Liu C,Chen S
Wed Dec 01 00:00:00 UTC 2021
Pterostilbene attenuates RIPK3-dependent hepatocyte necroptosis in alcoholic liver disease via SIRT2-mediated NFATc4 deacetylation.
Toxicology
Shao Y,Wang X,Zhou Y,Jiang Y,Wu R,Lu C
Wed Sep 01 00:00:00 UTC 2021
Cadmium exposure induces TNF-α-mediated necroptosis via FPR2/TGF-β/NF-κB pathway in swine myocardium.
Toxicology
Zhao X,Wang S,Li X,Liu H,Xu S
Thu Apr 15 00:00:00 UTC 2021
Toxoplasma gondii secreted effectors co-opt host repressor complexes to inhibit necroptosis.
Cell host & microbe
Rosenberg A,Sibley LD
Wed Jul 14 00:00:00 UTC 2021
Pterocephin A, a novel Triterpenoid Saponin from Pterocephalus hookeri induced liver injury by activation of necroptosis.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Wang R,Wei L,Dong Z,Meng F,Wang G,Zhou S,Lan X,Liao Z,Chen M
Sat May 01 00:00:00 UTC 2021
STAT3β Enhances Sensitivity to Concurrent Chemoradiotherapy by Inducing Cellular Necroptosis in Esophageal Squamous Cell Carcinoma.
Cancers
Zheng ZY,Yang PL,Luo W,Yu SX,Xu HY,Huang Y,Li RY,Chen Y,Xu XE,Liao LD,Wang SH,Huang HC,Li EM,Xu LY
Sun Feb 21 00:00:00 UTC 2021
Traditional herbal formula Wu-Mei-Wan alleviates TNBS-induced colitis in mice by inhibiting necroptosis through increasing RIPK3 O-GlcNAcylation.
Chinese medicine
Wu F,Shao Q,Cheng Z,Xiong X,Fang K,Zhao Y,Dong R,Xu L,Lu F,Chen G
Mon Aug 16 00:00:00 UTC 2021
New insights in acetaminophen toxicity: HMGB1 contributes by itself to amplify hepatocyte necrosis in vitro through the TLR4-TRIF-RIPK3 axis.
Scientific reports
Minsart C,Liefferinckx C,Lemmers A,Dressen C,Quertinmont E,Leclercq I,Devière J,Moreau R,Gustot T
Fri Mar 27 00:00:00 UTC 2020
A necroptotic-independent function of MLKL in regulating endothelial cell adhesion molecule expression.
Cell death & disease
Dai J,Zhang C,Guo L,He H,Jiang K,Huang Y,Zhang X,Zhang H,Wei W,Zhang Y,Lu L,Hu J
Fri Apr 24 00:00:00 UTC 2020
A necroptotic-independent function of MLKL in regulating endothelial cell adhesion molecule expression.
Cell death & disease
Dai J,Zhang C,Guo L,He H,Jiang K,Huang Y,Zhang X,Zhang H,Wei W,Zhang Y,Lu L,Hu J
Fri Apr 24 00:00:00 UTC 2020
RIP1/RIP3/MLKL mediates dopaminergic neuron necroptosis in a mouse model of Parkinson disease.
Laboratory investigation; a journal of technical methods and pathology
Lin QS,Chen P,Wang WX,Lin CC,Zhou Y,Yu LH,Lin YX,Xu YF,Kang DZ
Sun Mar 01 00:00:00 UTC 2020
Norfloxacin induces apoptosis and necroptosis in human corneal epithelial cells.
Toxicology in vitro : an international journal published in association with BIBRA
Yang T,Fan TJ,Xu B
Sat Aug 01 00:00:00 UTC 2020
Visfatin Plays a Significant Role in Alleviating Lipopolysaccharide-Induced Apoptosis and Autophagy Through PI3K/AKT Signaling Pathway During Acute Lung Injury in Mice.
Archivum immunologiae et therapiae experimentalis
Wu XT,Ansari AR,Pang XX,Li HZ,Zhang ZW,Luo Y,Arshad M,Song H
Thu Aug 01 00:00:00 UTC 2019
FKBP12 mediates necroptosis by initiating RIPK1-RIPK3-MLKL signal transduction in response to TNF receptor 1 ligation.
Journal of cell science
Wang Z,Feng J,Yu J,Chen G
Mon May 20 00:00:00 UTC 2019
Dexmedetomidine Preconditioning Protects Cardiomyocytes Against Hypoxia/Reoxygenation-Induced Necroptosis by Inhibiting HMGB1-Mediated Inflammation.
Cardiovascular drugs and therapy
Chen J,Jiang Z,Zhou X,Sun X,Cao J,Liu Y,Wang X
Fri Feb 01 00:00:00 UTC 2019
Quetiapine induces myocardial necroptotic cell death through bidirectional regulation of cannabinoid receptors.
Toxicology letters
Li X,Peng Z,Zhou Y,Wang J,Lin X,Dong X,Liu X,Jiang J,Jiang Y,Li L
Tue Oct 01 00:00:00 UTC 2019
Neferine, a Bisbenzylisoquinoline Alkaloid, Ameliorates Dextran Sulfate Sodium-Induced Ulcerative Colitis.
The American journal of Chinese medicine
Wu X,Guo Y,Min X,Pei L,Chen X
Tue Dec 18 00:00:00 UTC 2018
Neferine, a Bisbenzylisoquinoline Alkaloid, Ameliorates Dextran Sulfate Sodium-Induced Ulcerative Colitis.
The American journal of Chinese medicine
Wu X,Guo Y,Min X,Pei L,Chen X
Tue Dec 18 00:00:00 UTC 2018
Dihydrotanshinone I, a natural product, ameliorates DSS-induced experimental ulcerative colitis in mice.
Toxicology and applied pharmacology
Guo Y,Wu X,Wu Q,Lu Y,Shi J,Chen X
Sun Apr 01 00:00:00 UTC 2018
Dihydrotanshinone I, a natural product, ameliorates DSS-induced experimental ulcerative colitis in mice.
Toxicology and applied pharmacology
Guo Y,Wu X,Wu Q,Lu Y,Shi J,Chen X
Sun Apr 01 00:00:00 UTC 2018
Necrostatin-1 promotes ectopic periodontal tissue like structure regeneration in LPS-treated PDLSCs.
PloS one
Yan B,Zhang H,Dai T,Gu Y,Qiu X,Hu C,Liu Y,Wei K,Li D
Fri Apr 19 00:00:00 UTC 2019
Receptor-Interacting Protein 3/Caspase-8 May Regulate Inflammatory Response and Promote Tissue Regeneration in the Periodontal Microenvironment.
Medical science monitor : international medical journal of experimental and clinical research
Yan B,Wei K,Hou L,Dai T,Gu Y,Qiu X,Chen J,Feng Y,Cheng H,Yu Z,Zhang Y,Zhang H,Li D
Sun Jul 29 00:00:00 UTC 2018
Receptor-Interacting Protein 3/Caspase-8 May Regulate Inflammatory Response and Promote Tissue Regeneration in the Periodontal Microenvironment.
Medical science monitor : international medical journal of experimental and clinical research
Yan B,Wei K,Hou L,Dai T,Gu Y,Qiu X,Chen J,Feng Y,Cheng H,Yu Z,Zhang Y,Zhang H,Li D
Sun Jul 29 00:00:00 UTC 2018
Neuroprotective Effect of β-Caryophyllene on Cerebral Ischemia-Reperfusion Injury via Regulation of Necroptotic Neuronal Death and Inflammation: In Vivo and in Vitro.
Frontiers in neuroscience
Yang M,Lv Y,Tian X,Lou J,An R,Zhang Q,Li M,Xu L,Dong Z
Wed Sep 30 00:00:00 UTC 2020
Neuroprotective Effect of β-Caryophyllene on Cerebral Ischemia-Reperfusion Injury via Regulation of Necroptotic Neuronal Death and Inflammation: In Vivo and in Vitro.
Frontiers in neuroscience
Yang M,Lv Y,Tian X,Lou J,An R,Zhang Q,Li M,Xu L,Dong Z
Wed Sep 30 00:00:00 UTC 2020
Neuroprotective Effect of β-Caryophyllene on Cerebral Ischemia-Reperfusion Injury via Regulation of Necroptotic Neuronal Death and Inflammation: In Vivo and in Vitro.
Frontiers in neuroscience
Yang M,Lv Y,Tian X,Lou J,An R,Zhang Q,Li M,Xu L,Dong Z
Wed Sep 30 00:00:00 UTC 2020
Neuroprotective Effect of β-Caryophyllene on Cerebral Ischemia-Reperfusion Injury via Regulation of Necroptotic Neuronal Death and Inflammation: In Vivo and in Vitro.
Frontiers in neuroscience
Yang M,Lv Y,Tian X,Lou J,An R,Zhang Q,Li M,Xu L,Dong Z
Wed Sep 30 00:00:00 UTC 2020
A novel sgRNA selection system for CRISPR-Cas9 in mammalian cells.
Biochemical and biophysical research communications
Zhang H,Zhang X,Fan C,Xie Q,Xu C,Zhao Q,Liu Y,Wu X,Zhang H
Fri Mar 18 00:00:00 UTC 2016
A novel sgRNA selection system for CRISPR-Cas9 in mammalian cells.
Biochemical and biophysical research communications
Zhang H,Zhang X,Fan C,Xie Q,Xu C,Zhao Q,Liu Y,Wu X,Zhang H
Fri Mar 18 00:00:00 UTC 2016