Product References
Role of the Peli1-RIPK1 Signaling Axis in Methamphetamine-Induced Neuroinflammation.
ACS chemical neuroscience
Xu W,Yang T,Lou X,Chen J,Wang X,Hu M,An D,Gao R,Wang J,Chen X
Wed Mar 01 00:00:00 UTC 2023
Role of the Peli1-RIPK1 Signaling Axis in Methamphetamine-Induced Neuroinflammation.
ACS chemical neuroscience
Xu W,Yang T,Lou X,Chen J,Wang X,Hu M,An D,Gao R,Wang J,Chen X
Wed Mar 01 00:00:00 UTC 2023
Effect of doramectin on programmed cell death pathway in glioma cells.
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
Du S,Liang H,Zhou L,Chen C,Sun R,Zhang J,Meng X,Gao A
Sun Oct 01 00:00:00 UTC 2023
Liraglutide Attenuates Myocardial Ischemia/Reperfusion Injury Through the Inhibition of Necroptosis by Activating GLP-1R/PI3K/Akt Pathway.
Cardiovascular toxicology
Zhou G,Wu H,Yang J,Ye M,Liu D,Li Y,Zhang D,Zhang J,Yang Q,Liu Y
Sat Apr 01 00:00:00 UTC 2023
STING deficiency protects against wasp venom-induced acute kidney injury.
Inflammation research : official journal of the European Histamine Research Society ... [et al.]
Lv Y,Lu L,Yu F,Gao Z,Yuan H,Hu F
Sat Jul 01 00:00:00 UTC 2023
Repurposing of the FGFR inhibitor AZD4547 as a potent inhibitor of necroptosis by selectively targeting RIPK1.
Acta pharmacologica Sinica
Wang ZW,Zou FM,Wang AL,Yang J,Jin R,Wang BL,Shen LJ,Qi S,Liu J,Liu J,Wang WC,Liu QS
Sat Apr 01 00:00:00 UTC 2023
Echinacea Polyphenols Inhibit NLRP3-Dependent Pyroptosis, Apoptosis, and Necroptosis via Suppressing NO Production during Lipopolysaccharide-Induced Acute Lung Injury.
Journal of agricultural and food chemistry
Guo J,Luo Y,Zuo J,Teng J,Shen B,Liu X
Wed May 17 00:00:00 UTC 2023
Cisatracurium besylate rescues Mycobacterium Tuberculosis-infected macrophages from necroptosis and enhances the bactericidal effect of isoniazid.
International immunopharmacology
Wen Q,Zhang J,Zhang Z,Chen L,Liu H,Han Z,Chen Y,Wang K,Liu J,Sai N,Zhou X,Zhou C,Hu S,Ma L
Sat Jul 01 00:00:00 UTC 2023
Cisatracurium besylate rescues Mycobacterium Tuberculosis-infected macrophages from necroptosis and enhances the bactericidal effect of isoniazid.
International immunopharmacology
Wen Q,Zhang J,Zhang Z,Chen L,Liu H,Han Z,Chen Y,Wang K,Liu J,Sai N,Zhou X,Zhou C,Hu S,Ma L
Sat Jul 01 00:00:00 UTC 2023
Cisatracurium besylate rescues Mycobacterium Tuberculosis-infected macrophages from necroptosis and enhances the bactericidal effect of isoniazid.
International immunopharmacology
Wen Q,Zhang J,Zhang Z,Chen L,Liu H,Han Z,Chen Y,Wang K,Liu J,Sai N,Zhou X,Zhou C,Hu S,Ma L
Sat Jul 01 00:00:00 UTC 2023
Lactoferrin attenuated urban particulate matter-induced nephrotoxicity by regulating the CSF2/CENPE axis.
Environmental pollution (Barking, Essex : 1987)
Liu WC,Chiu HW,Chou CL,Chiu YJ,Lee YH
Wed Feb 01 00:00:00 UTC 2023
Pathologically high intraocular pressure induces mitochondrial dysfunction through Drp1 and leads to retinal ganglion cell PANoptosis in glaucoma.
Redox biology
Zeng Z,You M,Fan C,Rong R,Li H,Xia X
Thu Jun 01 00:00:00 UTC 2023
Deletion of Bak1 alleviates microglial necroptosis and neuroinflammation after experimental subarachnoid hemorrhage.
Journal of neurochemistry
Qiu X,Tao Q,Zhang L,Kuang C,Xie Y,Zhang L,Yin S,Peng J,Jiang Y
Wed Mar 01 00:00:00 UTC 2023
MLKL signaling regulates macrophage polarization in acute pancreatitis through CXCL10.
Cell death & disease
Peng C,Tu G,Wang J,Wang Y,Wu P,Yu L,Li Z,Yu X
Fri Feb 24 00:00:00 UTC 2023
Polysaccharide from Strongylocentrotus nudus eggs regulates intestinal epithelial autophagy through CD36/PI3K-Akt pathway to ameliorate inflammatory bowel disease.
International journal of biological macromolecules
Zhou M,Zhi J,Zhi J,Xiong Z,Wu F,Lu Y,Hu Q
Mon Jul 31 00:00:00 UTC 2023
Necroptosis of macrophage is a key pathological feature in biliary atresia via GDCA/S1PR2/ZBP1/p-MLKL axis.
Cell death & disease
Yang S,Chang N,Li W,Yang T,Xue R,Liu J,Zhang L,Yao X,Chen Y,Wang H,Yang L,Huang J,Li L
Wed Mar 01 00:00:00 UTC 2023
Necroptosis of macrophage is a key pathological feature in biliary atresia via GDCA/S1PR2/ZBP1/p-MLKL axis.
Cell death & disease
Yang S,Chang N,Li W,Yang T,Xue R,Liu J,Zhang L,Yao X,Chen Y,Wang H,Yang L,Huang J,Li L
Wed Mar 01 00:00:00 UTC 2023
Apoptosis-induced nuclear expulsion in tumor cells drives S100a4-mediated metastatic outgrowth through the RAGE pathway.
Nature cancer
Park WY,Gray JM,Holewinski RJ,Andresson T,So JY,Carmona-Rivera C,Hollander MC,Yang HH,Lee M,Kaplan MJ,Cappell SD,Yang L
Wed Mar 01 00:00:00 UTC 2023
Repositioning linifanib as a potent anti-necroptosis agent for sepsis.
Cell death discovery
Yu L,Yang K,He X,Li M,Gao L,Zha Y
Fri Feb 10 00:00:00 UTC 2023
Triptolide leads to hepatic intolerance to exogenous lipopolysaccharide and natural-killer-cell mediated hepatocellular damage by inhibiting MHC class I molecules.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Zhang H,Yuan Z,Wang J,Tang Q,Miao Y,Yuan Z,Huang X,Zhu Y,Nong C,Zhang L,Jiang Z,Yu Q
Sun Jan 01 00:00:00 UTC 2023
Repurposing crizotinib to target RIPK1-dependent cell death.
International immunology
Yu Y,Li M,Fu S,He X,Hu X,Zhu G,Wang J,You X,Mou Y,Ye Z,Wei J,Zha Y
Mon May 08 00:00:00 UTC 2023
Myo-inositol oxygenase overexpression exacerbates cadmium-induced kidney injury via oxidant stress and necroptosis.
American journal of physiology. Renal physiology
Zheng X,Deng F,Sharma I,Kanwar YS
Tue Mar 01 00:00:00 UTC 2022
Protective effect of inhibiting necroptosis on gentamicin-induced nephrotoxicity.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Hu BF,Gong Q,Chen SQ,Yue L,Ma WX,Wang F,Feng XW,Wang JN,Li C,Liu MM,Wang XF,Meng XM,Li J,Wen JG
Thu Sep 01 00:00:00 UTC 2022
Zinc finger protein 91 mediates necroptosis by initiating RIPK1-RIPK3-MLKL signal transduction in response to TNF receptor 1 ligation.
Toxicology letters
Zhong Y,Zhang ZH,Wang JY,Xing Y,Ri MH,Jin HL,Zuo HX,Li MY,Ma J,Jin X
Tue Mar 01 00:00:00 UTC 2022
L-OPA1 deficiency aggravates necroptosis of alveolar epithelial cells through impairing mitochondrial function during acute lung injury in mice.
Journal of cellular physiology
Jiang HL,Yang HH,Liu YB,Zhang CY,Zhong WJ,Guan XX,Jin L,Hong JR,Yang JT,Tan XH,Li Q,Zhou Y,Guan CX
Fri Jul 01 00:00:00 UTC 2022
L-OPA1 deficiency aggravates necroptosis of alveolar epithelial cells through impairing mitochondrial function during acute lung injury in mice.
Journal of cellular physiology
Jiang HL,Yang HH,Liu YB,Zhang CY,Zhong WJ,Guan XX,Jin L,Hong JR,Yang JT,Tan XH,Li Q,Zhou Y,Guan CX
Fri Jul 01 00:00:00 UTC 2022
Taurine inhibits necroptosis helps to alleviate inflammatory and injury induced by Klebsiella infection.
Veterinary immunology and immunopathology
Yin H,Wang Z,Yang S,Zheng X,Bao Y,Lin W,Huang C,Qiu L
Mon Aug 01 00:00:00 UTC 2022
Dysmyelination by Oligodendrocyte-Specific Ablation of Ninj2 Contributes to Depressive-Like Behaviors.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Sun Y,Chen X,Ou Z,Wang Y,Chen W,Zhao T,Liu C,Chen Y
Sat Jan 01 00:00:00 UTC 2022
Developmental exposure to chlorpyrifos causes neuroinflammation via necroptosis in mouse hippocampus and human microglial cell line.
Environmental pollution (Barking, Essex : 1987)
Tu Y,Yang Y,Wang Y,Wu N,Tao J,Yang G,You M
Thu Dec 01 00:00:00 UTC 2022
Developmental exposure to chlorpyrifos causes neuroinflammation via necroptosis in mouse hippocampus and human microglial cell line.
Environmental pollution (Barking, Essex : 1987)
Tu Y,Yang Y,Wang Y,Wu N,Tao J,Yang G,You M
Thu Dec 01 00:00:00 UTC 2022
Developmental exposure to chlorpyrifos causes neuroinflammation via necroptosis in mouse hippocampus and human microglial cell line.
Environmental pollution (Barking, Essex : 1987)
Tu Y,Yang Y,Wang Y,Wu N,Tao J,Yang G,You M
Thu Dec 01 00:00:00 UTC 2022
Developmental exposure to chlorpyrifos causes neuroinflammation via necroptosis in mouse hippocampus and human microglial cell line.
Environmental pollution (Barking, Essex : 1987)
Tu Y,Yang Y,Wang Y,Wu N,Tao J,Yang G,You M
Thu Dec 01 00:00:00 UTC 2022
Thioredoxin reductase 3 suppression promotes colitis and carcinogenesis via activating pyroptosis and necrosis.
Cellular and molecular life sciences : CMLS
Liu Q,Du P,Zhu Y,Zhang X,Cai J,Zhang Z
Sun Jan 30 00:00:00 UTC 2022
Ameliorative effects of epigallocatechin-3-gallate nanoparticles on 2,4-dinitrochlorobenzene induced atopic dermatitis: A potential mechanism of inflammation-related necroptosis.
Frontiers in nutrition
Han M,Wang X,Wang J,Lang D,Xia X,Jia Y,Chen Y
Sat Aug 27 00:00:00 UTC 2022
Enhanced nuclear localization of phosphorylated MLKL predicts adverse events in patients with dilated cardiomyopathy.
ESC heart failure
Fujita Y,Yano T,Kanamori H,Nagahara D,Muranaka A,Kouzu H,Mochizuki A,Koyama M,Nagano N,Fujito T,Nishikawa R,Kamiyama N,Tanaka M,Kuno A,Tanno M,Miura T
Sat Oct 01 00:00:00 UTC 2022
Serpina3c deficiency induced necroptosis promotes non-alcoholic fatty liver disease through β-catenin/Foxo1/TLR4 signaling.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Qian LL,Ji JJ,Jiang Y,Guo JQ,Wu Y,Yang Z,Ma GS,Yao YY
Sun May 01 00:00:00 UTC 2022
LncRNA 122049 suppresses apoptosis of renal tubular epithelial cells in ischemic AKI by targeting the miR-330-5p/ELK1 axis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Xiao Y,Li X,Qiu S,Wang Y,Zhang D
Fri Jul 01 00:00:00 UTC 2022
MiR-29a-3p Improves Acute Lung Injury by Reducing Alveolar Epithelial Cell PANoptosis.
Aging and disease
Cui Y,Wang X,Lin F,Li W,Zhao Y,Zhu F,Yang H,Rao M,Li Y,Liang H,Dai M,Liu B,Chen L,Han D,Lu R,Peng W,Zhang Y,Song C,Luo Y,Pan P
Wed Jun 01 00:00:00 UTC 2022
Targeting Cell Membranes, Depleting ROS by Dithiane and Thioketal-Containing Polymers with Pendant Cholesterols Delivering Necrostatin-1 for Glaucoma Treatment.
ACS nano
Rong R,Zhou X,Liang G,Li H,You M,Liang Z,Zeng Z,Xiao H,Ji D,Xia X
Tue Dec 27 00:00:00 UTC 2022
Caspase-8 is involved in pyroptosis, necroptosis and the maturation and release of IL-1β in Aspergillus fumigatus keratitis.
International immunopharmacology
Wang L,Yan H,Chen X,Lee J,Sun J,Liu G,Yang H,Lu D,Liu W,Che C
Thu Dec 01 00:00:00 UTC 2022
Necrostatin-1 Against Sevoflurane-Induced Cognitive Dysfunction Involves Activation of BDNF/TrkB Pathway and Inhibition of Necroptosis in Aged Rats.
Neurochemical research
Yin C,Zhang Q,Zhao J,Li Y,Yu J,Li W,Wang Q
Fri Apr 01 00:00:00 UTC 2022
Adenosine Kinase Inhibition Prevents Severe Acute Pancreatitis via Suppressing Inflammation and Acinar Cell Necroptosis.
Frontiers in cell and developmental biology
Sun S,Han Y,Zhang C,Liu H,Wang B,Cao S,Yuan Q,Wei S,Chen Y
Wed Mar 16 00:00:00 UTC 2022
Pressure Drives Rapid Burst-Like Coordinated Cellular Motion from 3D Cancer Aggregates.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Raghuraman S,Schubert AS,Bröker S,Jurado A,Müller A,Brandt M,Vos BE,Hofemeier AD,Abbasi F,Stehling M,Wittkowski R,Ivaska J,Betz T
Tue Feb 01 00:00:00 UTC 2022
Contribution of Necroptosis to Myofiber Death in Idiopathic Inflammatory Myopathies.
Arthritis & rheumatology (Hoboken, N.J.)
Peng QL,Zhang YM,Liu YC,Liang L,Li WL,Tian XL,Zhang L,Yang HX,Lu X,Wang GC
Wed Jun 01 00:00:00 UTC 2022
Ligand-based substituent-anchoring design of selective receptor-interacting protein kinase 1 necroptosis inhibitors for ulcerative colitis therapy.
Acta pharmaceutica Sinica. B
Zhu J,Xin M,Xu C,He Y,Zhang W,Wang Z,Zhuang C
Fri Oct 01 00:00:00 UTC 2021
PARP1-mediated PARylation activity is essential for oligodendroglial differentiation and CNS myelination.
Cell reports
Wang Y,Zhang Y,Zhang S,Kim B,Hull VL,Xu J,Prabhu P,Gregory M,Martinez-Cerdeno V,Zhan X,Deng W,Guo F
Tue Oct 05 00:00:00 UTC 2021
4-Hydroxy-2-Nonenal Promotes Cardiomyocyte Necroptosis via Stabilizing Receptor-Interacting Serine/Threonine-Protein Kinase 1.
Frontiers in cell and developmental biology
Zhai X,Wang W,Sun S,Han Y,Li J,Cao S,Li R,Xu T,Yuan Q,Wang J,Wei S,Chen Y
Fri Oct 22 00:00:00 UTC 2021
Differential role of MLKL in alcohol-associated and non-alcohol-associated fatty liver diseases in mice and humans.
JCI insight
Miyata T,Wu X,Fan X,Huang E,Sanz-Garcia C,Ross CKC,Roychowdhury S,Bellar A,McMullen MR,Dasarathy J,Allende DS,Caballeria J,Sancho-Bru P,McClain CJ,Mitchell M,McCullough AJ,Radaeva S,Barton B,Szabo G,Dasarathy S,Nagy LE
Mon Feb 22 00:00:00 UTC 2021
Inhibition of adenosine kinase attenuates myocardial ischaemia/reperfusion injury.
Journal of cellular and molecular medicine
Wang W,Wang B,Sun S,Cao S,Zhai X,Zhang C,Zhang Q,Yuan Q,Sun Y,Xue M,Ma J,Xu F,Wei S,Chen Y
Mon Mar 01 00:00:00 UTC 2021
RIPK3-Dependent Necroptosis Is Induced and Restricts Viral Replication in Human Astrocytes Infected With Zika Virus.
Frontiers in cellular and infection microbiology
Wen C,Yu Y,Gao C,Qi X,Cardona CJ,Xing Z
Mon Jul 05 00:00:00 UTC 2021
Metformin attenuates hypothalamic inflammation via downregulation of RIPK1-independent microglial necroptosis in diet-induced obese mice.
Cell death discovery
Li X,Cai Y,Luo J,Ding J,Yao G,Xiao X,Tang Y,Liang Z
Mon Nov 08 00:00:00 UTC 2021
Expression of the ACE2 Virus Entry Protein in the Nervus Terminalis Reveals the Potential for an Alternative Route to Brain Infection in COVID-19.
Frontiers in cellular neuroscience
Bilinska K,von Bartheld CS,Butowt R
Thu Nov 02 00:00:00 UTC 2023
A new perspective of triptolide-associated hepatotoxicity: the relevance of NF- B and NF- B-mediated cellular FLICE-inhibitory protein.
Acta pharmaceutica Sinica. B
Yuan Z,Yuan Z,Hasnat M,Zhang H,Liang P,Sun L,Jiang Z,Zhang L
Fri May 01 00:00:00 UTC 2020
A new perspective of triptolide-associated hepatotoxicity: the relevance of NF- B and NF- B-mediated cellular FLICE-inhibitory protein.
Acta pharmaceutica Sinica. B
Yuan Z,Yuan Z,Hasnat M,Zhang H,Liang P,Sun L,Jiang Z,Zhang L
Fri May 01 00:00:00 UTC 2020
M10, a Myricetin-3-O-b-D-Lactose Sodium Salt, Prevents Ulcerative Colitis Through Inhibiting Necroptosis in Mice.
Frontiers in pharmacology
Zhou XL,Yang J,Qu XJ,Meng J,Miao RR,Cui SX
Sun Apr 17 00:00:00 UTC 2022
Protective effect of astaxanthin against SnS2 nanoflowers induced testes toxicity by suppressing RIPK1-RIPK3-MLKL signaling in mice.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Yuan L,Liang P,Qu Y,An T,Wang J,Deng X,Bai L,Shen P,Bai D
Sun Nov 01 00:00:00 UTC 2020
Insights into mechanisms of pranoprofen-induced apoptosis and necroptosis in human corneal stromal cells.
Toxicology letters
Lin Y,Yu M,Fan T
Sun Mar 01 00:00:00 UTC 2020
The bromodomain protein BRD4 positively regulates necroptosis via modulating MLKL expression.
Cell death and differentiation
Xiong Y,Li L,Zhang L,Cui Y,Wu C,Li H,Chen K,Yang Q,Xiang R,Hu Y,Huang S,Wei Y,Yang S
Tue Oct 01 00:00:00 UTC 2019
The bromodomain protein BRD4 positively regulates necroptosis via modulating MLKL expression.
Cell death and differentiation
Xiong Y,Li L,Zhang L,Cui Y,Wu C,Li H,Chen K,Yang Q,Xiang R,Hu Y,Huang S,Wei Y,Yang S
Tue Oct 01 00:00:00 UTC 2019
The bromodomain protein BRD4 positively regulates necroptosis via modulating MLKL expression.
Cell death and differentiation
Xiong Y,Li L,Zhang L,Cui Y,Wu C,Li H,Chen K,Yang Q,Xiang R,Hu Y,Huang S,Wei Y,Yang S
Tue Oct 01 00:00:00 UTC 2019
The bromodomain protein BRD4 positively regulates necroptosis via modulating MLKL expression.
Cell death and differentiation
Xiong Y,Li L,Zhang L,Cui Y,Wu C,Li H,Chen K,Yang Q,Xiang R,Hu Y,Huang S,Wei Y,Yang S
Tue Oct 01 00:00:00 UTC 2019
A new perspective of triptolide-associated hepatotoxicity: Liver hypersensitivity upon LPS stimulation.
Toxicology
Yuan Z,Zhang H,Hasnat M,Ding J,Chen X,Liang P,Sun L,Zhang L,Jiang Z
Fri Feb 15 00:00:00 UTC 2019
A new perspective of triptolide-associated hepatotoxicity: Liver hypersensitivity upon LPS stimulation.
Toxicology
Yuan Z,Zhang H,Hasnat M,Ding J,Chen X,Liang P,Sun L,Zhang L,Jiang Z
Fri Feb 15 00:00:00 UTC 2019
FKBP12 mediates necroptosis by initiating RIPK1-RIPK3-MLKL signal transduction in response to TNF receptor 1 ligation.
Journal of cell science
Wang Z,Feng J,Yu J,Chen G
Mon May 20 00:00:00 UTC 2019
TRADD Mediates RIPK1-Independent Necroptosis Induced by Tumor Necrosis Factor.
Frontiers in cell and developmental biology
Wang L,Chang X,Feng J,Yu J,Chen G
Mon Sep 28 00:00:00 UTC 2020
Quetiapine induces myocardial necroptotic cell death through bidirectional regulation of cannabinoid receptors.
Toxicology letters
Li X,Peng Z,Zhou Y,Wang J,Lin X,Dong X,Liu X,Jiang J,Jiang Y,Li L
Tue Oct 01 00:00:00 UTC 2019
Quetiapine induces myocardial necroptotic cell death through bidirectional regulation of cannabinoid receptors.
Toxicology letters
Li X,Peng Z,Zhou Y,Wang J,Lin X,Dong X,Liu X,Jiang J,Jiang Y,Li L
Tue Oct 01 00:00:00 UTC 2019
