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Invitrogen
MMACHC Polyclonal Antibody
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Product Details
PA5-21798
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human MMACHC. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_11154251
Product Specific Information
Recommended positive controls: 293T, A431, H1299, HeLaS3, HepG2, Raji, mouse brain.
Predicted reactivity: Mouse (85%), Rat (86%), Pig (91%), Rhesus Monkey (97%), Bovine (90%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The exact function of the MMACHC protein is not known, however, its C-terminal region shows similarity to TonB, a bacterial protein involved in energy transduction for cobalamin (vitamin B12) uptake. Hence, it is postulated that this protein may have a role in the binding and intracellular trafficking of cobalamin. Mutations in this gene are associated with methylmalonic aciduria and homocystinuria type cblC.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Alkylcobalamin:glutathione S-alkyltransferase; CblC; Cyanocobalamin reductase (cyanide-eliminating); Cyanocobalamin reductase / alkylcobalamin dealkylase; Methylmalonic aciduria and homocystinuria type C protein; methylmalonic aciduria and homocystinuria type C protein homolog; MMACHC; RP11-291L19.3
Gene Aliases: 1810037K07Rik; cblC; MMACHC; RGD1310806
UniProt ID: (Human) Q9Y4U1, (Mouse) Q9CZD0
Entrez Gene ID: (Human) 25974, (Mouse) 67096, (Rat) 313520
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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