Proteintech

MMP1 Polyclonal Antibody

View all (41) MMP1 antibodies

Questions & Answers

Questions & Answers

Antibody Testing Data (7)

MMP1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

MMP1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FIGURE: 1 / 7

MMP1 Antibody (26585-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human cervical cancer tissue slide using 26585-1-AP ( MMP1 Antibody) at dilution of 1:200 (under 40x lens). heat mediated antigen retrieved with Tris-EDTA buffer (pH 9).

MMP1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

MMP1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

MMP1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

MMP1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

MMP1 Antibody in Western Blot (WB)

MMP1 Antibody in Western Blot (WB)

MMP1 Antibody in Immunoprecipitation (IP)

Product Image Gallery

MMP1 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human cervical cancer tissue slide using 26585-1-AP ( MMP1 Antibody) at dilution of 1:200 (under 40x lens). heat mediated antigen retrieved with Tris-EDTA buffer (pH 9).

MMP1 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human cervical cancer tissue slide using 26585-1-AP ( MMP1 Antibody) at dilution of 1:200 (under 10x lens). heat mediated antigen retrieved with Tris-EDTA buffer (pH 9).

MMP1 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using 26585-1-AP (MMP1 Antibody) at dilution of 1:200 (under 40x lens). heat mediated antigen retrieved with Tris-EDTA buffer (pH 9).

MMP1 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using 26585-1-AP (MMP1 Antibody) at dilution of 1:200 (under 10x lens). heat mediated antigen retrieved with Tris-EDTA buffer (pH 9).

MMP1 Antibody in Western Blot (WB) — NIH/3T3 cells were subjected to SDS PAGE followed by western blot with 26585-1-AP (MMP1 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

MMP1 Antibody in Western Blot (WB) — A375 cells were subjected to SDS PAGE followed by western blot with 26585-1-AP ( MMP1 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

MMP1 Antibody in Immunoprecipitation (IP) — IP result of anti-MMP1 (IP:26585-1-AP, 4ug; Detection:26585-1-AP 1:300) with Raji cells lysate 4000ug.

Product Details

26585-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:200-1:1,000

View 2 publications 2 publications

Immunohistochemistry (IHC)

-

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:100-1:400

-

Immunoprecipitation (IP)

0.5-4.0 µg

View 1 publication 1 publication

Miscellaneous PubMed (MISC)

-

View 1 publication 1 publication

Not applicable (N/A)

-

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

MMP1 Fusion Protein Ag25073 (428-469 aa encoded by BC013875)

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.37 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: AVFMKDGFF YFFHGTRQYK FDPKTKRILT LQKANSWFNC RKN (428-469 aa encoded by BC013875)

Target Information

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes a secreted enzyme which breaks down the interstitial collagens, types I, II, and III. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Exosomal MMP-1 transfers metastasis potential in triple-negative breast cancer through PAR1-mediated EMT.

Breast cancer research and treatment

Zhu Y,Tao Z,Chen Y,Lin S,Zhu M,Ji W,Liu X,Li T,Hu X

Sun May 01 00:00:00 UTC 2022

Exosomal MMP-1 transfers metastasis potential in triple-negative breast cancer through PAR1-mediated EMT.

Breast cancer research and treatment

Zhu Y,Tao Z,Chen Y,Lin S,Zhu M,Ji W,Liu X,Li T,Hu X

Sun May 01 00:00:00 UTC 2022

Exosomal MMP-1 transfers metastasis potential in triple-negative breast cancer through PAR1-mediated EMT.

Breast cancer research and treatment

Zhu Y,Tao Z,Chen Y,Lin S,Zhu M,Ji W,Liu X,Li T,Hu X

Sun May 01 00:00:00 UTC 2022

Exosomal MMP-1 transfers metastasis potential in triple-negative breast cancer through PAR1-mediated EMT.

Breast cancer research and treatment

Zhu Y,Tao Z,Chen Y,Lin S,Zhu M,Ji W,Liu X,Li T,Hu X

Sun May 01 00:00:00 UTC 2022

Exosomal MMP-1 transfers metastasis potential in triple-negative breast cancer through PAR1-mediated EMT.

Breast cancer research and treatment

Zhu Y,Tao Z,Chen Y,Lin S,Zhu M,Ji W,Liu X,Li T,Hu X

Sun May 01 00:00:00 UTC 2022

Exosomal MMP-1 transfers metastasis potential in triple-negative breast cancer through PAR1-mediated EMT.

Breast cancer research and treatment

Zhu Y,Tao Z,Chen Y,Lin S,Zhu M,Ji W,Liu X,Li T,Hu X

Sun May 01 00:00:00 UTC 2022

Exhausting circ_0136474 and Restoring miR-766-3p Attenuate Chondrocyte Oxidative Injury in IL-1β-Induced Osteoarthritis Progression Through Regulating DNMT3A.

Frontiers in genetics

Zhu H,Zhu S,Shang X,Meng X,Jing S,Yu L,Deng Y

Tue Jun 08 00:00:00 UTC 2021

Icariin inhibits MMP‑1, MMP‑3 and MMP‑13 expression through MAPK pathways in IL‑1β‑stimulated SW1353 chondrosarcoma cells.

Molecular medicine reports

Zeng L,Rong XF,Li RH,Wu XY

Mon May 01 00:00:00 UTC 2017

Icariin inhibits MMP‑1, MMP‑3 and MMP‑13 expression through MAPK pathways in IL‑1β‑stimulated SW1353 chondrosarcoma cells.

Molecular medicine reports

Zeng L,Rong XF,Li RH,Wu XY

Mon May 01 00:00:00 UTC 2017

Bioinformatics

Protein Aliases: Collagenase; collagenase-like A; Fibroblast collagenase; Interstitial collagenase; Interstitial collagenase A; matrix metallo protease; matrix metallopeptidase 1 (interstitial collagenase); matrix metalloprotease 1; matrix metalloproteinase 1; matrix metalloproteinase 1a (interstitial collagenase); Matrix metalloproteinase-1; Matrix metalloproteinase-1a; Matrix metalloproteinase1; Mcol-A; MMP; MMP-1; MMP-1a; MMPs

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Gene Aliases: CLG; CLGN; Mcol-A; McolA; MMP1; Mmp1a

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UniProt ID: (Human) P03956, (Mouse) Q9EPL5

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Entrez Gene ID: (Human) 4312, (Mouse) 83995

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endopeptidase activity metalloendopeptidase activity serine-type endopeptidase activity calcium ion binding zinc ion binding peptidase activity metallopeptidase activity hydrolase activity metal ion binding

proteolysis viral process extracellular matrix disassembly collagen catabolic process positive regulation of protein oligomerization cellular protein metabolic process leukocyte migration positive regulation of fibroblast migration positive regulation of smooth muscle cell migration

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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