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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • MMP1 Antibodies

          Invitrogen

          MMP1 Recombinant Rabbit Monoclonal Antibody (HL1259)

          View all (41) MMP1 antibodies
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          Datasheet
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          Cite MMP1 Recombinant Rabbit Monoclonal Antibody (HL1259)

          • Antibody Testing Data (3)
          MMP1 Antibody in Immunocytochemistry (ICC/IF)
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          MMP1 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 3

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          MMP1 Antibody (MA5-46976) in ICC/IF

          Immunofluorescent analysis of MMP1 in MDA-MB-231 cells. Cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: MMP1 stained by MMP1 monoclonal antibody (Product # MA5-46976) diluted at 1:200. Red: alpha Tubulin, a cytoskeleton marker, stained by alpha Tubulin antibody [GT114] diluted at 1:1,000. Blue: Fluoroshield with DAPI. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          MMP1 Antibody in Immunocytochemistry (ICC/IF)
          MMP1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          MMP1 Antibody in Western Blot (WB)

          Product Details

          MA5-46976

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          Assay-dependent
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:100-1:1,000
          -

          Immunocytochemistry (ICC/IF)

          Assay-dependent
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Expression System

          HEK293 cells

          Class

          Recombinant Monoclonal

          Type

          Antibody

          Clone

          HL1259

          Immunogen

          Recombinant protein encompassing a sequence within the center region of Human MMP1. The exact sequence is proprietary.

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Protein A

          Storage buffer

          PBS

          Contains

          no preservative

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2938048

          Product Specific Information

          Store as concentrated solution.

          Centrifuge briefly prior to opening vial.

          Target Information

          Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes a secreted enzyme which breaks down the interstitial collagens, types I, II, and III. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: Collagenase; Fibroblast collagenase; Interstitial collagenase; matrix metallo protease; matrix metallopeptidase 1 (interstitial collagenase); matrix metalloprotease 1; matrix metalloproteinase 1; Matrix metalloproteinase-1; Matrix metalloproteinase1; MMP; MMP-1; MMPs

          View more View less

          Gene Aliases: CLG; CLGN; MMP1

          View more View less

          UniProt ID: (Human) P03956

          View more View less

          Entrez Gene ID: (Human) 4312

          View more View less

          Function(s)
          endopeptidase activity metalloendopeptidase activity serine-type endopeptidase activity calcium ion binding zinc ion binding
          Process(es)
          proteolysis viral process extracellular matrix disassembly collagen catabolic process positive regulation of protein oligomerization cellular protein metabolic process leukocyte migration
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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