Product References
Engineering exosomes derived from subcutaneous fat MSCs specially promote cartilage repair as miR-199a-3p delivery vehicles in Osteoarthritis.
Journal of nanobiotechnology
Zhao S,Xiu G,Wang J,Wen Y,Lu J,Wu B,Wang G,Yang D,Ling B,Du D,Xu J
MA5-14238 was used in Immunohistochemistry to develop an efficient MSCsSC-Exos-based strategy for OA therapy and promote the application of targeted-MSCsSC-Exos for drug delivery in the future.
Fri Sep 22 00:00:00 UTC 2023
Irisin Modulates Inflammatory, Angiogenic, and Osteogenic Factors during Fracture Healing.
International journal of molecular sciences
Oranger A,Zerlotin R,Buccoliero C,Sanesi L,Storlino G,Schipani E,Kozloff KM,Mori G,Colaianni G,Colucci S,Grano M
MA5-14238 was used in Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot to suggest that irisin can contribute to fracture repair by reducing inflammation and promoting vessel invasion, matrix degradation, and bone formation, supporting its possible role as a novel molecule for fracture treatment.
Tue Jan 17 00:00:00 UTC 2023
Evaluation of Matrix Metalloproteases by Artificial Intelligence Techniques in Negative Biopsies as New Diagnostic Strategy in Prostate Cancer.
International journal of molecular sciences
Eiro N,Medina A,Gonzalez LO,Fraile M,Palacios A,Escaf S,Fernández-Gómez JM,Vizoso FJ
MA5-14238 was used in Immunohistochemistry to evaluate the expression of various matrix metalloproteases (MMPs) and tissue inhibitor of MMPs (TIMP-3) in prostate tissues before and after prostate cancer (PCa) diagnosis using machine learning techniques.
Mon Apr 10 00:00:00 UTC 2023
ADSCs increase the autophagy of chondrocytes through decreasing miR-7-5p in Osteoarthritis rats by targeting ATG4A.
International immunopharmacology
Zhao S,Liu Y,Wang J,Wen Y,Wu B,Yang D,Wang G,Xiu G,Ling B,Du D,Xu J
MA5-14238 was used in Immunohistochemistry to demonstrate a potential role for ADSCs based therapeutics for preventing of articular cartilage destruction and extracellular matrix (ECM) degradation in OA.
Sat Jul 01 00:00:00 UTC 2023
Drugging the circadian clock feedback cycle to ameliorate cartilage degeneration.
The FEBS journal
He T,Pang S,Wang H,Yun H,Hao X,Jia L,Liu H,Wang D,Wang D,Xu H,Jie Q,Yang L,Zheng C
Published figure using MMP13 monoclonal antibody (Product # MA5-14238) in Immunocytochemistry
Tue Nov 01 00:00:00 UTC 2022
Drugging the circadian clock feedback cycle to ameliorate cartilage degeneration.
The FEBS journal
He T,Pang S,Wang H,Yun H,Hao X,Jia L,Liu H,Wang D,Wang D,Xu H,Jie Q,Yang L,Zheng C
Published figure using MMP13 monoclonal antibody (Product # MA5-14238) in Immunocytochemistry
Tue Nov 01 00:00:00 UTC 2022
Modeling early changes associated with cartilage trauma using human-cell-laden hydrogel cartilage models.
Stem cell research & therapy
He C,Clark KL,Tan J,Zhou H,Tuan RS,Lin H,Wu S,Alexander PG
MA5-14238 was used in Immunohistochemistry to show that traumatic impacts delivered to engineered cartilage constructs induced PTOA-like changes in the encapsulated cells.
Thu Aug 04 00:00:00 UTC 2022
HE4 Overexpression by Ovarian Cancer Promotes a Suppressive Tumor Immune Microenvironment and Enhanced Tumor and Macrophage PD-L1 Expression.
Journal of immunology (Baltimore, Md. : 1950)
Rowswell-Turner RB,Singh RK,Urh A,Yano N,Kim KK,Khazan N,Pandita R,Sivagnanalingam U,Hovanesian V,James NE,Ribeiro JR,Kadambi S,Linehan DC,Moore RG
MA5-14238 was used in Western Blotting to identify HE4 as a mediator of tumor-immune suppression in ovarian cancer, highlighting this molecule as a potential therapeutic target for the treatment of this devastating disease.
Sat May 15 00:00:00 UTC 2021
Low-Molecular-Weight Collagen Peptide Ameliorates Osteoarthritis Progression through Promoting Extracellular Matrix Synthesis by Chondrocytes in a Rabbit Anterior Cruciate Ligament Transection Model.
Journal of microbiology and biotechnology
Lee MH,Kim HM,Chung HC,Kim DU,Lee JH
MA5-14238 was used immunohistochemistry (paraffin) examine whether the oral administration of low-molecular-weight collagen peptide containing 3% Gly-Pro-Hyp with >15% tripeptide content could ameliorate osteoarthritis progression using a rabbit anterior cruciate ligament transection model of induced OA and chondrocytes isolated from a patient with OA.
Thu Oct 28 00:00:00 UTC 2021
Low-Molecular-Weight Collagen Peptide Ameliorates Osteoarthritis Progression through Promoting Extracellular Matrix Synthesis by Chondrocytes in a Rabbit Anterior Cruciate Ligament Transection Model.
Journal of microbiology and biotechnology
Lee MH,Kim HM,Chung HC,Kim DU,Lee JH
MA5-14238 was used immunohistochemistry (paraffin) examine whether the oral administration of low-molecular-weight collagen peptide containing 3% Gly-Pro-Hyp with >15% tripeptide content could ameliorate osteoarthritis progression using a rabbit anterior cruciate ligament transection model of induced OA and chondrocytes isolated from a patient with OA.
Thu Oct 28 00:00:00 UTC 2021
Investigation of the role of matrix metalloproteinases in the genetic etiology of Alzheimer's disease.
Neurobiology of aging
Hoogmartens J,Hens E,Engelborghs S,De Deyn PP,van der Zee J,Van Broeckhoven C,Cacace R
MA5-14238 was used in Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot to hypothesize a gain-of-function disease mechanism for the missense mutations found in patients.
Sun Aug 01 00:00:00 UTC 2021
Increased matrix metalloproteinase levels and perineuronal net proteolysis in the HIV-infected brain; relevance to altered neuronal population dynamics.
Experimental neurology
Bozzelli PL,Caccavano A,Avdoshina V,Mocchetti I,Wu JY,Conant K
MA5-14238 was used in Western Blotting to show that levels of PNN-degrading matrix metalloproteinases (MMPs) are elevated in HIV-infected post-mortem human brain tissue.
Wed Jan 01 00:00:00 UTC 2020
Therapeutic effect of Resveratrol in the treatment of osteoarthritis via the MALAT1/miR-9/NF-κB signaling pathway.
Experimental and therapeutic medicine
Zhang G,Zhang H,You W,Tang X,Li X,Gong Z
Published figure using MMP13 monoclonal antibody (Product # MA5-14238) in Immunohistochemistry
Sun Mar 01 00:00:00 UTC 2020
TAP2, a peptide antagonist of Toll-like receptor 4, attenuates pain and cartilage degradation in a monoiodoacetate-induced arthritis rat model.
Scientific reports
Park H,Hong J,Yin Y,Joo Y,Kim Y,Shin J,Kwon HH,Shin N,Shin HJ,Beom J,Kim DW,Kim J
MA5-14238 was used in Immunohistochemistry to investigate whether TAP2, a peptide antagonist of TLR4, reduces the monoiodoacetate (MIA)-induced arthritic pain and cartilage degradation in rats.
Thu Oct 15 00:00:00 UTC 2020
TAP2, a peptide antagonist of Toll-like receptor 4, attenuates pain and cartilage degradation in a monoiodoacetate-induced arthritis rat model.
Scientific reports
Park H,Hong J,Yin Y,Joo Y,Kim Y,Shin J,Kwon HH,Shin N,Shin HJ,Beom J,Kim DW,Kim J
MA5-14238 was used in Immunohistochemistry to investigate whether TAP2, a peptide antagonist of TLR4, reduces the monoiodoacetate (MIA)-induced arthritic pain and cartilage degradation in rats.
Thu Oct 15 00:00:00 UTC 2020
The Activity of KIF14, Mieap, and EZR in a New Type of the Invasive Component, Torpedo-Like Structures, Predetermines the Metastatic Potential of Breast Cancer.
Cancers
Gerashchenko TS,Zolotaryova SY,Kiselev AM,Tashireva LA,Novikov NM,Krakhmal NV,Cherdyntseva NV,Zavyalova MV,Perelmuter VM,Denisov EV
MA5-14238 was used in Immunohistochemistry to identify molecules associated with breast cancer invasion and metastasis.
Wed Jul 15 00:00:00 UTC 2020
HIV-1 Tat promotes astrocytic release of CCL2 through MMP/PAR-1 signaling.
Glia
Bozzelli PL,Yin T,Avdoshina V,Mocchetti I,Conant KE,Maguire-Zeiss KA
MA5-14238 was used in Western Blotting to show the release of CCL2 is controlled by Tat-mediated matrix metalloproteinases and protease-activated receptor 1 signaling.
Sun Sep 01 00:00:00 UTC 2019
S100A4 Elevation Empowers Expression of Metastasis Effector Molecules in Human Breast Cancer.
Cancer research
Ismail TM,Bennett D,Platt-Higgins AM,Al-Medhity M,Barraclough R,Rudland PS
Published figure using MMP13 monoclonal antibody (Product # MA5-14238) in Immunohistochemistry
Wed Feb 01 00:00:00 UTC 2017
Analysis of tryptase-positive mast cells and immunoexpression of MMP-9 and MMP-13 in periapical lesions.
International endodontic journal
Andrade AL,Santos EM,Carmo AF,Freitas RA,Galvão HC
MA514238 was used in immunohistochemistry - paraffin section to measure tryptase, MMP-9, and MMP-13 expression in periapical lesions and correlate expression with the type of lesion, intensity of the inflammatory infiltrate, and thickness of the epithelial lining
Mon May 01 00:00:00 UTC 2017
CCN1 Regulates Chondrocyte Maturation and Cartilage Development.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Zhang Y,Sheu TJ,Hoak D,Shen J,Hilton MJ,Zuscik MJ,Jonason JH,O'Keefe RJ
MA5-14238 was used in immunohistochemistry to research regulation of cartilage development and chondrocyte maturation by CCN1
Tue Mar 01 00:00:00 UTC 2016
Expression and Clinical Significance of Metalloproteases and Their Inhibitors by Endothelial Cells From Invasive Breast Carcinomas.
Clinical breast cancer
Cid S,Eiro N,González LO,Beridze N,Vazquez J,Vizoso FJ
MA5-14238 was used in immunohistochemistry - paraffin section to study the clinical significance and expression of metalloproteases and their inhibitors in invasive breast carcinoma endothelial cells
Mon Aug 01 00:00:00 UTC 2016
MMP-13 In-Vivo Molecular Imaging Reveals Early Expression in Lung Adenocarcinoma.
PloS one
Salaün M,Peng J,Hensley HH,Roder N,Flieder DB,Houlle-Crépin S,Abramovici-Roels O,Sabourin JC,Thiberville L,Clapper ML
MA5-14238 was used in immunohistochemistry - paraffin section to research early expression of MMP-13 in lung adenocarcinoma by in-vivo molecular imaging
Thu Apr 28 00:00:00 UTC 2016
Expression of matrix metalloproteinases and their inhibitors in different immunohistochemical-based molecular subtypes of breast cancer.
BMC cancer
Kim GE,Lee JS,Choi YD,Lee KH,Lee JH,Nam JH,Choi C,Kim SS,Park MH,Yoon JH,Kweon SS
MA5-14238 was used in Immunohistochemistry to assess the prevalence and clinical significance of matrix metalloproteinase and tissue inhibitor of metalloproteinase expression in invasive breast cancer to determine its association with immunohistochemical-based molecular classification.
Tue Dec 16 00:00:00 UTC 2014
Quantification of excision repair cross-complementing group 1 and survival in p16-negative squamous cell head and neck cancers.
Clinical cancer research : an official journal of the American Association for Cancer Research
Mehra R,Zhu F,Yang DH,Cai KQ,Weaver J,Singh MK,Nikonova AS,Golemis EA,Flieder DB,Cooper HS,Lango M,Ridge JA,Burtness B
MA5-14238 was used in immunohistochemistry to study the prognostic value of ERRC1 in p16-negative squamous cell head and neck cancers
Sun Dec 01 00:00:00 UTC 2013
Markers of breast cancer stromal fibroblasts in the primary tumour site associated with lymph node metastasis: a systematic review including our case series.
Bioscience reports
Folgueira MA,Maistro S,Katayama ML,Roela RA,Mundim FG,Nanogaki S,de Bock GH,Brentani MM
MA5-14238 was used in immunohistochemistry to perform a systematic literature and case survey to identify breast cancer-associated fibroblast markers that are prognostic of lymph node metastasis
Thu Dec 12 00:00:00 UTC 2013
RBP-Jκ-dependent Notch signaling is required for murine articular cartilage and joint maintenance.
Arthritis and rheumatism
Mirando AJ,Liu Z,Moore T,Lang A,Kohn A,Osinski AM,O'Keefe RJ,Mooney RA,Zuscik MJ,Hilton MJ
MA5-14238 was used in immunohistochemistry to study the role of Notch signaling in murine articular cartilage and joint maintenance
Tue Oct 01 00:00:00 UTC 2013
Chronic heat treatment causes skin wrinkle formation and oxidative damage in hairless mice.
Mechanisms of ageing and development
Shin MH,Seo JE,Kim YK,Kim KH,Chung JH
MA5-14238 was used in western blot to study the underlying mechanisms of skin wrinkle formation and oxidative damage in hairless mice induced by chronic heat treatment
Tue Jul 10 00:00:00 UTC 2012
Skeletal analysis of the long bone abnormality (lbab/lbab) mouse, a novel chondrodysplastic C-type natriuretic peptide mutant.
Calcified tissue international
Kondo E,Yasoda A,Tsuji T,Fujii T,Miura M,Kanamoto N,Tamura N,Arai H,Kunieda T,Nakao K
MA5-14238 was used in immunohistochemistry to study lbab/lbab mice as a model of chondrodysplasia
Sun Apr 01 00:00:00 UTC 2012
The use of different analgesics in orthodontic tooth movements.
The Angle orthodontist
Hammad SM,El-Hawary YM,El-Hawary AK
MA5-14238 was used in immunohistochemistry to study the effect of different analgesics on tooth movement and bone resorption
Sat Sep 01 00:00:00 UTC 2012
Immunoexpression of matrix metalloproteinases and their inhibitors in different areas of oral squamous cell carcinoma.
Australian dental journal
Suarez-Roa ML,Asbun-Bojalil J,Ruiz-Godoy LM,Meneses-García AA
MA5-14238 was used in immunohistochemistry to study the expression of MMPs and TIMPs in different histopathological regions of oral squamous cell carcinomas
Sat Sep 01 00:00:00 UTC 2012
Collagenase-3 expression by tumor cells and gelatinase B expression by stromal fibroblast-like cells are associated with biochemical recurrence after radical prostatectomy in patients with prostate cancer.
World journal of urology
Escaff S,Fernández JM,González LO,Suárez A,González-Reyes S,González JM,Vizoso FJ
MA5-14238 was used in immunohistochemistry to investigate the prognostic significance of collagenase-3 and gelatinase B in prostate cancer recurrence
Sat Oct 01 00:00:00 UTC 2011
Expression of matrix metalloproteinases and their inhibitors in squamous cell carcinoma of the tonsil and their clinical significance.
Clinical and experimental otorhinolaryngology
Lee SY,Park SY,Kim SH,Choi EC
MA5-14238 was used in immunohistochemistry to study the role and clinical significance of MMPs and their inhibitors in squamous cell carcinoma of the tonsil
Wed Jun 01 00:00:00 UTC 2011
Chondroprotective effect of alendronate in a rabbit model of osteoarthritis.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society
Shirai T,Kobayashi M,Nishitani K,Satake T,Kuroki H,Nakagawa Y,Nakamura T
MA5-14238 was used in immunohistochemistry to study the effects of alendronate on cartilage degeneration in a rabbit model of osteoarthritis
Sat Oct 01 00:00:00 UTC 2011
Study of matrix metalloproteinases and their inhibitors in prostate cancer.
British journal of cancer
Escaff S,Fernández JM,González LO,Suárez A,González-Reyes S,González JM,Vizoso FJ
MA5-14238 was used in immunohistochemistry to study the expression of MMPs and TIMPs in prostate cancer
Tue Mar 02 00:00:00 UTC 2010
Expression of metalloproteases and their inhibitors by tumor and stromal cells in ductal carcinoma in situ of the breast and their relationship with microinvasive events.
Journal of cancer research and clinical oncology
González LO,González-Reyes S,Junquera S,Marín L,González L,Del Casar JM,González JM,Vizoso F
MA5-14238 was used in immunohistochemistry to study the immunohistochemical expression of MMPs and TIMPs in ductal carcinoma in situ of the breast
Wed Sep 01 00:00:00 UTC 2010
Expression of metalloproteases and their inhibitors in different histological types of breast cancer.
Journal of cancer research and clinical oncology
Del Casar JM,González-Reyes S,González LO,González JM,Junquera S,Bongera M,García MF,Andicoechea A,Serra C,Vizoso FJ
MA5-14238 was used in immunohistochemistry to study the expression of MMPs and TIMPs in different histological subtypes of breast cancer
Tue Jun 01 00:00:00 UTC 2010
Expression of metalloproteases and their inhibitors in primary tumors and in local recurrences after mastectomy for breast cancer.
Journal of cancer research and clinical oncology
del Casar JM,Carreño G,González LO,Junquera S,González-Reyes S,González JM,Bongera M,Merino AM,Vizoso FJ
MA5-14238 was used in immunohistochemistry to study the expression of MMPs and TIMPs in breast cancer primary tumors and in local recurrences following mastectomy
Thu Jul 01 00:00:00 UTC 2010
MMP-13 expression in keratocyst odontogenic tumour associated with NBCCS and sporadic keratocysts.
Oral diseases
Leonardi R,Matthews JB,Caltabiano R,Greco M,Lombardo C,Loreto C,Santarelli A,Lo Muzio L
MA5-14238 was used in immunohistochemistry to investigate the changes of MMP-13 level in NBCCS-associated keratocyst odontogenic tumour
Mon Nov 01 00:00:00 UTC 2010
Immunohistochemical study of matrix metalloproteinases and their inhibitors in pure and mixed invasive and in situ ductal carcinomas of the breast.
Human pathology
Gonzalez LO,Junquera S,del Casar JM,González L,Marín L,González-Reyes S,Andicoechea A,González-Fernández R,González JM,Pérez-Fernández R,Vizoso FJ
MA5-14238 was used in immunohistochemistry to study the immunohistochemical expression of MMPs and TIMPs in differerent types of breast carcinoma
Thu Jul 01 00:00:00 UTC 2010
Comparative analysis and clinical value of the expression of metalloproteases and their inhibitors by intratumor stromal fibroblasts and those at the invasive front of breast carcinomas.
Breast cancer research and treatment
Del Casar JM,González LO,Alvarez E,Junquera S,Marín L,González L,Bongera M,Vázquez J,Vizoso FJ
MA5-14238 was used in immunohistochemistry to study the clinical significance MMP and TIMP expression by intratumor stromal and invasive front fibroblasts in breast carcinoma
Wed Jul 01 00:00:00 UTC 2009
Differentiation of synovial CD-105(+) human mesenchymal stem cells into chondrocyte-like cells through spheroid formation.
Journal of cellular biochemistry
Arufe MC,De la Fuente A,Fuentes-Boquete I,De Toro FJ,Blanco FJ
MA5-14238 was used in immunohistochemistry to exmaine the process of the differetiation of synovial mesenchymal stem cells into chondrocyte-like cells
Tue Sep 01 00:00:00 UTC 2009
Treatment of arthritis with a selective inhibitor of c-Fos/activator protein-1.
Nature biotechnology
Aikawa Y,Morimoto K,Yamamoto T,Chaki H,Hashiramoto A,Narita H,Hirono S,Shiozawa S
MA5-14238 was used in immunohistochemistry to study the effects of a selective inhibitor of c-Fos/activator protein-1 in a pre-clinical arthritis model
Tue Jul 01 00:00:00 UTC 2008
Differential expression of stromal MMP-1, MMP-9 and TIMP-1 in basal cell carcinomas of immunosuppressed patients and controls.
Virchows Archiv : an international journal of pathology
Boyd S,Tolvanen K,Virolainen S,Kuivanen T,Kyllönen L,Saarialho-Kere U
MA5-14238 was used in immunohistochemistry to study the expression of stromal matrix maetalloproteases and TIMP-1 in basal cell carcinomas of immunosuppressed patients
Tue Jan 01 00:00:00 UTC 2008
Nifedipine regulated periodontal ligament remodeling: an experimental study in rats.
Acta odontologica Scandinavica
Zhang MM,Feng DF,Shao P,Sun TT,Wang L,Yang BF
MA5-14238 was used in immunohistochemistry to investigate the impact of nifedipine on periodontal ligament remodeling in rats
Thu Feb 26 00:00:00 UTC 2009
Is collagenase-3 (MMP-13) expression in chondrosarcoma of the jaws a true marker for tumor aggressiveness?
Diagnostic pathology
Zyada MM,Shamaa AA
MA5-14238 was used in immunohistochemistry to study whether MMP13 expression in chondrosarcoma of the jaws a true marker for tumor aggressiveness
Fri Jun 13 00:00:00 UTC 2008
Tumor-derived matrix metalloproteinase-13 (MMP-13) correlates with poor prognoses of invasive breast cancer.
BMC cancer
Zhang B,Cao X,Liu Y,Cao W,Zhang F,Zhang S,Li H,Ning L,Fu L,Niu Y,Niu R,Sun B,Hao X
MA5-14238 was used in immunohistochemistry to investigate the prognostic value of matrix metalloproteinase-13 in invasive breast cancer patients
Fri Mar 28 00:00:00 UTC 2008
Overexpression of matrix metalloproteinases and their inhibitors in mononuclear inflammatory cells in breast cancer correlates with metastasis-relapse.
British journal of cancer
González LO,Pidal I,Junquera S,Corte MD,Vázquez J,Rodríguez JC,Lamelas ML,Merino AM,García-Muñiz JL,Vizoso FJ
MA5-14238 was used in immunohistochemistry to study the overexpression of MMPs and TIMPs in mononuclear inflammatory cells in breast cancer and the correlation with metastatic relapse
Mon Oct 08 00:00:00 UTC 2007
Study of matrix metalloproteinases and their inhibitors in breast cancer.
British journal of cancer
Vizoso FJ,González LO,Corte MD,Rodríguez JC,Vázquez J,Lamelas ML,Junquera S,Merino AM,García-Muñiz JL
MA5-14238 was used in immunohistochemistry to study the role of MMPs and TIMPs in breast cancer
Mon Mar 26 00:00:00 UTC 2007
Soft tissue reactions to bioactive glass 13-93 combined with chitosan.
Journal of biomedical materials research. Part A
Asikainen AJ,Hagström J,Sorsa T,Noponen J,Kellomäki M,Juuti H,Lindqvist C,Hietanen J,Suuronen R
MA5-14238 was used in immunohistochemistry to study the histological and immunohistochemical reactions to a bioactive glass mesh combined with chitosan in rabbits
Thu Nov 01 00:00:00 UTC 2007
MMP-13 (collagenase 3) immunolocalisation during initial orthodontic tooth movement in rats.
Acta histochemica
Leonardi R,Talic NF,Loreto C
MA5-14238 was used in immunohistochemistry to study MMP-13 localization during initial orthodontic tooth movement in rats
Thu Jul 19 00:00:00 UTC 2007
MMP-21 is upregulated at early stages of melanoma progression but disappears with more aggressive phenotype.
Virchows Archiv : an international journal of pathology
Kuivanen T,Ahokas K,Virolainen S,Jahkola T,Hölttä E,Saksela O,Saarialho-Kere U
MA5-14238 was used in immunohistochemistry to study the expression of MMP-21 at different stages of melanoma progression
Thu Dec 01 00:00:00 UTC 2005
