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Invitrogen
MMP7 Polyclonal Antibody
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Product Details
PA5-79686
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
E.coli-derived mouse MMP7 recombinant protein (Position: Y95-L264).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 4mg trehalose
Contains
no preservative
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2746801
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: Rat Brain Tissue. IHC: mouse kidney tissue, rat intestines tissue.
Target Information
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22. 3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: HGNC:7174; Matrilysin; matrilysin, uterine; Matrin; matrix metallo protease; matrix metalloproteinase 7; Matrix metalloproteinase 7 (matrilysin); Matrix metalloproteinase-7; MMP; MMP 7; MMP-7; MMPs; PUMP 1; Pump 1 protease; Pump-1 protease; Uterine metalloproteinase
Gene Aliases: MAT; Mmp-7; Mmp7; MPMM
UniProt ID: (Rat) P50280
Entrez Gene ID: (Rat) 25335, (Mouse) 17393
antibacterial peptide secretion
antibacterial peptide biosynthetic process
proteolysis
aging
collagen catabolic process
response to nutrient levels
regulation of cell proliferation
response to drug
defense response to bacterium
estrous cycle
defense response to Gram-negative bacterium
defense response to Gram-positive bacterium
maternal process involved in female pregnancy
cellular response to mechanical stimulus
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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