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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • MMP-9 Antibodies

          Proteintech

          MMP9 (N-terminal) Polyclonal Antibody

          1,017 References
          View all (62) MMP-9 antibodies
          Datasheet
          Protocols
          Questions & Answers
          Datasheet
          Protocols
          Questions & Answers

          Cite MMP9 (N-terminal) Polyclonal Antibody

          • Antibody Testing Data (26)
          MMP9 (N-terminal) Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.
          MMP9 (N-terminal) Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 26

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          MMP9 (N-terminal) Antibody (10375-2-AP) in ICC/IF

          Immunofluorescent analysis of HeLa cells using 10375-2-AP (MMP9 (N-terminal) antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
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          MMP9 (N-terminal) Antibody in Immunocytochemistry (ICC/IF)
          MMP9 (N-terminal) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          MMP9 (N-terminal) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          MMP9 (N-terminal) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          MMP9 (N-terminal) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          MMP9 (N-terminal) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          MMP9 (N-terminal) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          MMP9 (N-terminal) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          MMP9 (N-terminal) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          MMP9 (N-terminal) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          MMP9 (N-terminal) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          MMP9 (N-terminal) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          MMP9 (N-terminal) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          MMP9 (N-terminal) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          MMP9 (N-terminal) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          MMP9 (N-terminal) Antibody in Western Blot (WB)
          MMP9 (N-terminal) Antibody in Western Blot (WB)
          MMP9 (N-terminal) Antibody in Western Blot (WB)
          MMP9 (N-terminal) Antibody in Western Blot (WB)
          MMP9 (N-terminal) Antibody in Western Blot (WB)
          MMP9 (N-terminal) Antibody in Western Blot (WB)
          MMP9 (N-terminal) Antibody in Western Blot (WB)
          MMP9 (N-terminal) Antibody in Western Blot (WB)
          MMP9 (N-terminal) Antibody in Western Blot (WB)
          MMP9 (N-terminal) Antibody in Flow Cytometry (Flow)
          MMP9 (N-terminal) Antibody in Immunoprecipitation (IP)

          Product Details

          10375-2-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:1,000
          View 822 publications 822 publications

          Immunohistochemistry (IHC)

          -
          View 126 publications 126 publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:500
          -

          Immunocytochemistry (ICC/IF)

          1:20-1:200
          View 52 publications 52 publications

          Flow Cytometry (Flow)

          Assay-dependent
          -

          ELISA (ELISA)

          -
          View 1 publication 1 publication

          Immunoprecipitation (IP)

          0.5-4.0 µg
          View 2 publications 2 publications

          Miscellaneous PubMed (MISC)

          -
          View 4 publications 4 publications

          Not applicable (N/A)

          -
          View 10 publications 10 publications
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Published species

          Hamster, Human, Mouse, Plant, Rabbit, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          MMP9 (N-terminal) Fusion Protein Ag0552 (1-100 aa encoded by BC006093)
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.27 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Product Specific Information

          Immunogen sequence: MSLWQPLVL VLLVLGCCFA APRQRQSTLV LFPGDLRTNL TDRQLAEEYL YRYGYTRVAE MRGESKSLGP ALLLLQKQLS LPETGELDSA TLKAMRTPRC G (1-100 aa encoded by BC006093)

          Target Information

          MMP9 (matrix metallopeptidase 9, GELB, CLG4B) is a matrix metalloproteinase, a family of zinc and calcium-dependent endopeptidases that degrade extracellular matrix proteins. MMP9 is secreted as a 92kDa zymogen and cleavage of pro-MMP9 results in the active enzyme with a molecular weight of 82kDa. MMP9 has a gelatin-binding domain consisting of three fibronectin type II units, a catalytic domain containing the zinc-binding site, a proline-rich type V collagen-homologous domain and a hemopexin-like domain. MMP9 is produced by monocytes, macrophages, neutrophils, keratinocytes, fibroblasts, osteoclasts and endothelial cells, and is involved in inflammatory responses, tissue remodeling, wound healing, tumor growth and metastasis. MMP9 is supplied by bone marrow-derived cells and contributes to skin carcinogenesis. Further, MMP9 degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling. Studies have shown that elevated MMP9 is associated with progression of idiopathic atrial fibrillation and aortic aneurysm.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: 92 kDa gelatinase; 92 kDa type IV collagenase; 92-kDa type IV collagenase; 92kD gelatinase; 92kD type IV collagenase; 92kDa gelatinase; 92kDa type IV collagenase; collagenase type IVB; Gel B; Gelatinase B; Gelatinase-B; GELB; macrophage gelatinase; matrix metallo protease; matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase); matrix metalloproteinase 9; matrix metalloproteinase 9 (gelatinase B 92-kDa type IV collagenase); matrix metalloproteinase 9 (gelatinase B, 92-kDa type IV collagenase); matrix metalloproteinase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase); Matrix metalloproteinase-9; Matrix metalloproteinase9; MMP; MMP-9; MMPs; type V collagenase

          View more View less

          Gene Aliases: AW743869; B/MMP9; CLG4B; GELB; MANDP2; MMP-9; MMP9; pro-MMP-9

          View more View less

          UniProt ID: (Human) P14780, (Rat) P50282, (Mouse) P41245

          View more View less

          Entrez Gene ID: (Human) 4318, (Rat) 81687, (Mouse) 17395

          View more View less

          Function(s)
          endopeptidase activity metalloendopeptidase activity serine-type endopeptidase activity protein binding collagen binding metallopeptidase activity zinc ion binding identical protein binding fibronectin binding peptidase activity protein complex binding hydrolase activity metal ion binding
          Process(es)
          skeletal system development ossification response to hypoxia kidney development positive regulation of leukocyte migration proteolysis response to oxidative stress embryo implantation parturition aging response to nutrient response to radiation response to heat response to mechanical stimulus response to high light intensity response to organic substance response to organic cyclic compound transformation of host cell by virus extracellular matrix organization collagen catabolic process positive regulation of synaptic plasticity response to estradiol response to lipopolysaccharide response to retinoic acid response to vitamin A response to tumor necrosis factor response to nicotine endodermal cell differentiation response to drug positive regulation of apoptotic process response to ethanol positive regulation of angiogenesis negative regulation of fibroblast proliferation tissue remodeling leukocyte migration protein oligomerization positive regulation of keratinocyte migration response to hyperoxia cellular response to lipopolysaccharide cellular response to iron(III) ion cellular response to cytokine stimulus cellular response to interleukin-1 cellular response to tumor necrosis factor cellular response to low-density lipoprotein particle stimulus cellular response to cell-matrix adhesion positive regulation of receptor binding negative regulation of cation channel activity positive regulation of protein phosphorylation negative regulation of apoptotic process positive regulation of DNA binding positive regulation of epidermal growth factor receptor signaling pathway positive regulation of release of cytochrome c from mitochondria negative regulation of intrinsic apoptotic signaling pathway negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway extracellular matrix disassembly macrophage differentiation ephrin receptor signaling pathway positive regulation of vascular smooth muscle cell proliferation
          It has to be done as per old AB suggested Products section.
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