Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: MAFPEPKPR PPELPQKRLK TLDCGQGAVR AVRFNVDGNY CLTCGSDKTL KLWNPLRGTL LRTYSGHGYE VLDAAGSFDN SSLCSGGGDK AVVLWDVASG QVVRKFRGHA GKVNTVQFNE EATVILSGSI DSSIRCWDCR SRRPEPVQTL DEARDGVSSV KVSDHEILAG SVDGRVRRYD LRMGQLFSDY VGSPITCTCF SRDGQCTLVS SLDSTLRLLD KDTGELLGEY KGHKNQEYKL DCCLSERDTH VVSCSEDGKV FFWDLVEGAL ALALPVGSGV VQSLAYHPTE PCLLTAMGGS VQCWREEAYE AEDGAG (1-315 aa encoded by B C005870)
MORG1 is a member of the WD-40 protein family. The protein is proposed to function as a molecular scaffold for various multimeric protein complexes. The protein associates with several components of the extracellular signal-regulated kinase (ERK) pathway, and promotes ERK activity in response to serum or other signals. The protein also interacts with egl nine homolog 3 (EGLN3, also known as PHD3) and regulates expression of hypoxia-inducible factor 1, and has been purified as part of the spliceosome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: MAPK cascade scaffold protein; MAPK organizer 1; MGC4238; Mitogen-activated protein kinase organizer 1; WD repeat domain-containing protein 83
Gene Aliases: 1500041N16Rik; MORG1; WDR83
UniProt ID: (Human) Q9BRX9, (Mouse) Q9DAJ4
Entrez Gene ID: (Human) 84292, (Mouse) 67836
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