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Invitrogen
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FIGURE: 1 / 1
Immunogen sequence: AHLAGRGIRL RHFRKGKEMK LLAYDDDFDF NFQEFQYLKE EQTILPGDNL ITECRYNTKD RAEMTWGGLS TRSEMCLSYL LYYPRINLTR CASIPDIMEQ LQFIGVKEIY RPVTTWPFII KSPKQYKNLS FMDAMNKFKW TKKEGLSFNK LVLSLPVNVR CSKTDNAEWS IQGMTALPPD IERPYKAEPL VCGTSSSSSL H; Positive Samples: U-87MG, H460, A-431, Jurkat, Raji, Mouse uterus, Rat brain; Cellular Location: Endoplasmic reticulum membrane, Single-pass type I membrane protein
The MOXD1 (Monooxygenase, DBH-like 1) gene encodes a protein that is part of the copper type II, ascorbate-dependent monooxygenase family, which includes enzymes such as dopamine beta-hydroxylase. Located on chromosome 6, the MOXD1 protein plays a role in the biosynthesis of bioactive amines, though its specific substrate and biological functions are less well characterized compared to its family members. This enzyme's activity is implicated in various physiological processes, including the metabolism of neurotransmitters and regulation of blood pressure. Research has suggested that MOXD1 might be involved in oncogenesis, with altered expression observed in certain cancer types. Further studies are needed to elucidate its precise physiological roles and potential as a therapeutic target.
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Protein Aliases: DBH-like monooxygenase protein 1; DBH-related protein; dopamine-oxygenase; Monooxygenase X; monooxygenase, DBH-like 1
Gene Aliases: 3230402N08Rik; Dbhr; dJ248E1.1; MNCb-5203; MOX; MOXD1; PRO5780; UNQ2493/PRO5780
UniProt ID: (Human) Q6UVY6, (Mouse) Q9CXI3
Entrez Gene ID: (Human) 26002, (Mouse) 59012, (Rat) 294119
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