Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Product Details
PA5-68046
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthesized peptide derived from human MOZ.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2691720
Product Specific Information
Predicted to react with Mouse and Rat samples.
Target Information
Histone acetyltransferase that acetylates lysine residues in histone H3 and histone H4 (in vitro). Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. May act as a transcriptional coactivator for RUNX1 and RUNX2. Acetylates p53/TP53 at 'Lys-120' and 'Lys-382' and controls its transcriptional activity via association with PML.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Histone acetyltransferase KAT6A; histone acetyltransferase MYST3; K(lysine) acetyltransferase 6A; Monocytic leukemia zinc finger homolog; Monocytic leukemia zinc finger protein; MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3; MYST histone acetyltransferase (monocytic leukemia) 3; MYST-3; runt-related transcription factor binding protein 2; Runt-related transcription factor-binding protein 2; Zinc finger protein 220
Gene Aliases: 1500036M03; 9930021N24Rik; KAT6A; MOZ; MRD32; MYST-3; MYST3; RUNXBP2; ZC2HC6A; Zfp220; ZNF220
UniProt ID: (Human) Q92794, (Rat) Q5TKR9
Entrez Gene ID: (Human) 7994, (Mouse) 244349, (Rat) 306571
DNA binding
transcription coactivator activity
histone acetyltransferase activity
protein binding
transcription factor binding
zinc ion binding
acetyltransferase activity
chromatin binding
transferase activity
transferase activity, transferring acyl groups
transferase activity, transferring acyl groups other than amino-acyl groups
metal ion binding
heart morphogenesis
nucleosome assembly
transcription, DNA-templated
regulation of transcription, DNA-templated
protein acetylation
positive regulation of gene expression
chromatin modification
histone acetylation
myeloid cell differentiation
somatic stem cell population maintenance
embryonic hemopoiesis
aorta morphogenesis
negative regulation of sequence-specific DNA binding transcription factor activity
histone H3 acetylation
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
face morphogenesis
cellular senescence
DNA packaging
regulation of signal transduction by p53 class mediator
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support