Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Proteintech
MPEG1 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Product Details
23960-1-AP
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
MPEG1 Fusion Protein Ag21055 (25-370 aa encoded by BC104997)
Conjugate
Form
Liquid
Concentration
0.36 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: EMDEVGVQK CKNALKLPVL EVLPGGGWDN LRNVDMGRVM ELTYSNCRTT EDGQYIIPDE IFTIPQKQSN LEMNSEILES WANYQSSTSY SINTELSLFS KVNGKFSTEF QRMKTLQVKD QAITTRVQVR NLVYTVKINP TLELSSGFRK ELLDISDRLE NNQTRMATYL AELLVLNYGT HVTTSVDAGA ALIQEDHLRA SFLQDSQSSR SAVTASAGLA FQNTVNFKFE ENYTSQNVLT KSYLSNRTNS RVQSIGGVPF YPGITLQAWQ QGITNHLVAI DRSGLPLHFF INPNMLPDLP GPLVKKVSKT VETAVKRYYT FNTYPGCTDL NSPNFNFQAN TDDGSCE (25-370 aa encoded by BC104997)
Target Information
The MPEG1 (Macrophage Expressed Gene 1) gene encodes a protein known as Perforin-2, which is part of the immune system and plays a crucial role in host defense mechanisms. Located on chromosome 11, MPEG1/Perforin-2 is primarily expressed in macrophages, dendritic cells, and other immune cells. The protein functions by forming pores in the membranes of pathogenic bacteria, leading to their lysis and destruction. This pore-forming capability is integral to the innate immune response, providing a rapid means to target and eliminate intracellular pathogens. MPEG1's activity contributes significantly to the antimicrobial arsenal of the innate immune system, and deficiencies in this protein can lead to increased susceptibility to infections. Ongoing research is focused on understanding how MPEG1/Perforin-2 can be leveraged or augmented to enhance immune responses and potential therapeutic applications in infectious disease and immunotherapy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: macrophage expressed gene 1; Macrophage gene 1 protein; Macrophage-expressed gene 1 protein; MGC150002; MGC150003; P-2; perforin 2; Perforin-2
Gene Aliases: MPEG1; Mpg-1; MPG1; MPS1
UniProt ID: (Human) Q2M385
Entrez Gene ID: (Human) 219972
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support