Proteintech

MPP7 Polyclonal Antibody

MPP7 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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MPP7 Antibody (12983-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human ovary tumor using 12983-1-AP (MPP7 antibody) at dilution of 1:100 (under 10x lens).

MPP7 Antibody in Immunoprecipitation (IP)

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Product Details

12983-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:4,000

View 2 publications 2 publications

Immunohistochemistry (IHC)

View 2 publications 2 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

View 1 publication 1 publication

Immunoprecipitation (IP)

0.5-4.0 µg

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

MPP7 Fusion Protein Ag3612 (269-576 aa encoded by BC038105)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.3 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: DATWWQAKH EADANPRAGL IPSKHFQERR LALRRPEILV QPLKVSNRKS SGFRRSFRLS RKDKKTNKSM YECKKSDQYD TADVPTYEEV TPYRRQTNEK YRLVVLVGPV GVGLNELKRK LLISDTQHYG VTVPHTTRAR RSQESDGVEY IFISKHLFET DVQNNKFIEY GEYKNNYYGT SIDSVRSVLA KNKVCLLDVQ PHTVKHLRTL EFKPYVIFIK PPSIERLRET RKNAKIISSR DDQGAAKPFT EEDFQEMIKS AQIMESQYGH LFDKIIINDD LTVAFNELKT TFDKLETETH WVPVSWLHS (269-576 aa encoded by BC038105)

Target Information

Acts as an important adapter that promotes epithelial cell polarity and tight junction formation via its interaction with DLG1. Involved in the assembly of protein complexes at sites of cell-cell contact.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

MPP7 as a Novel Biomarker of Esophageal Cancer: MPP7 Knockdown Inhibits Esophageal Cancer Cell Migration and Invasion.

Life (Basel, Switzerland)

Li Z,Tang Y,Cai J,Wu S,Song F

Mon Sep 05 00:00:00 UTC 2022

MPP7 as a Novel Biomarker of Esophageal Cancer: MPP7 Knockdown Inhibits Esophageal Cancer Cell Migration and Invasion.

Life (Basel, Switzerland)

Li Z,Tang Y,Cai J,Wu S,Song F

Mon Sep 05 00:00:00 UTC 2022

MPP7 promotes the migration and invasion of breast cancer cells via EGFR/AKT signaling.

Cell biology international

Liao W,Fan L,Li M,Deng H,Yang A,Liu F

Sat May 01 00:00:00 UTC 2021

MPP7 promotes the migration and invasion of breast cancer cells via EGFR/AKT signaling.

Cell biology international

Liao W,Fan L,Li M,Deng H,Yang A,Liu F

Sat May 01 00:00:00 UTC 2021

Post-genome wide association studies and functional analyses identify association of MPP7 gene variants with site-specific bone mineral density.

Human molecular genetics

Xiao SM,Kung AW,Gao Y,Lau KS,Ma A,Zhang ZL,Liu JM,Xia W,He JW,Zhao L,Nie M,Fu WZ,Zhang MJ,Sun J,Kwan JS,Tso GH,Dai ZJ,Cheung CL,Bow CH,Leung AY,Tan KC,Sham PC

Sun Apr 01 00:00:00 UTC 2012

Post-genome wide association studies and functional analyses identify association of MPP7 gene variants with site-specific bone mineral density.

Human molecular genetics

Xiao SM,Kung AW,Gao Y,Lau KS,Ma A,Zhang ZL,Liu JM,Xia W,He JW,Zhao L,Nie M,Fu WZ,Zhang MJ,Sun J,Kwan JS,Tso GH,Dai ZJ,Cheung CL,Bow CH,Leung AY,Tan KC,Sham PC

Sun Apr 01 00:00:00 UTC 2012

Bioinformatics

Protein Aliases: MAGUK p55 subfamily member 7; membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)

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Gene Aliases: 1110068J02Rik; 2810038M04Rik; 5430426E14Rik; AI415104; Gm955; MPP7

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UniProt ID: (Human) Q5T2T1, (Mouse) Q8BVD5, (Rat) Q5U2Y3

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Entrez Gene ID: (Human) 143098, (Mouse) 75739, (Rat) 307035

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Function(s)

protein binding protein domain specific binding protein complex scaffold signaling adaptor activity protein heterodimerization activity cadherin binding involved in cell-cell adhesion

Process(es)

positive regulation of protein complex assembly bicellular tight junction assembly protein localization to adherens junction positive regulation of signal transduction establishment of cell polarity cell-cell adhesion

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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MPP7 Polyclonal Antibody

MPP7 Antibody (12983-1-AP) in IHC (P)

Product Details

12983-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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