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Proteintech
MR1 Polyclonal Antibody
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Product Details
13260-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
MR1 Fusion Protein Ag3849 (20-260 aa encoded by BC012485)
Conjugate
Form
Liquid
Concentration
0.15 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: SDSRTHSLR YFRLGVSDPI HGVPEFISVG YVDSHPITTY DSVTRQKEPR APWMAENLAP DHWERYTQLL RGWQQMFKVE LKRLQRHYNH SDNVAHTIKQ AWEANQHELL YQKNWLEEEC IAWLKRFLEY GKDTLQRTEP PLVRVNRKET FPGVTALFCK AHGFYPPEIY MTWMKNGEEI VQEIDYGDIL PSGDGTYQAW ASIELDPQSS NLYSCHVEHC GVHMVLQVPQ ESETIPLVMK AV (20-260 aa encoded by BC012485)
Target Information
Antigen-presenting molecule specialized in presenting microbial vitamin B metabolites. Involved in the development and expansion of a small population of T-cells expressing an invariant T-cell receptor alpha chain called mucosal-associated invariant T- cells (MAIT). MAIT lymphocytes are preferentially located in the gut lamina propria and therefore may be involved in monitoring commensal flora or serve as a distress signal. Expression and MAIT cell recognition seem to be ligand-dependent.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Class I histocompatibility antigen-like protein; histocompatibility-2 complex class 1-like sequence; Major histocompatibility complex class I-related gene protein; major histocompatibility complex, class I-like sequence; MCH class I; MHC class I-like antigen MR-1; MHC class I-like sequence; MHC class I-related gene protein; MHC class-I related-gene protein
Gene Aliases: H2ls; HLALS; MR1; Mr1a
UniProt ID: (Human) Q95460, (Mouse) Q8HWB0, (Rat) O19477
Entrez Gene ID: (Human) 3140, (Mouse) 15064, (Rat) 25119
cytokine production involved in immune response
antigen processing and presentation of peptide antigen via MHC class I
immune response
signal transduction
antigen processing and presentation
interleukin-1 beta production
interleukin-17 production
innate immune response
defense response to Gram-negative bacterium
immune system process
positive regulation of T cell mediated cytotoxicity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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