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Abnova
MR1 Monoclonal Antibody (5E9)
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Product Details
H00003140-M03
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
5E9
Immunogen
MR1 (NP_001522, 201 a.a. approximately 300 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Sandwich ELISA (Recombinant protein).
Immunogen sequence: TEPPLVRVNR KETFPGVTAL FCKAHGFYPP EIYMTWMKNG EEIVQEIDYG DILPSGDGTY QAWASIELDP QSSNLYSCHV EHCGVHMVLQ VPQESETIPL
Target Information
Antigen-presenting molecule specialized in presenting microbial vitamin B metabolites. Involved in the development and expansion of a small population of T-cells expressing an invariant T-cell receptor alpha chain called mucosal-associated invariant T- cells (MAIT). MAIT lymphocytes are preferentially located in the gut lamina propria and therefore may be involved in monitoring commensal flora or serve as a distress signal. Expression and MAIT cell recognition seem to be ligand-dependent.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Class I histocompatibility antigen-like protein; Major histocompatibility complex class I-related gene protein; major histocompatibility complex, class I-like sequence; MHC class I-like antigen MR-1; MHC class I-related gene protein; MHC class-I related-gene protein
Gene Aliases: HLALS; MR1
UniProt ID: (Human) Q95460
Entrez Gene ID: (Human) 3140
cytokine production involved in immune response
antigen processing and presentation of peptide antigen via MHC class I
immune response
signal transduction
antigen processing and presentation
interleukin-1 beta production
interleukin-17 production
innate immune response
defense response to Gram-negative bacterium
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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