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Immunogen sequence: MANGTNASAP YYSYEYYLDY LDLIPVDEKK LKAHKHS
Highest antigen sequence identity to the following orthologs: Mouse - 84%, Rat - 81%.
MRAP encodes a melanocortin receptor-interacting protein. The encoded protein regulates trafficking and function of the melanocortin 2 receptor in the adrenal gland. The encoded protein can also modulate signaling of other melanocortin receptors. Mutations in this gene have been associated with familial glucocorticoid deficiency type 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: B27; Fat cell-specific low molecular weight protein; Fat tissue-specific low MW protein; Melanocortin-2 receptor accessory protein
Gene Aliases: B27; C21orf61; FALP; FGD2; GCCD2; MRAP
UniProt ID: (Human) Q8TCY5
Entrez Gene ID: (Human) 56246
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