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Invitrogen
MRG15 Polyclonal Antibody
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FIGURE: 1 / 3
MRG15 Antibody (PA5-78349) in ICC/IF
MRG15 Polyclonal Antibody detects MRG15 protein at nucleus by immunofluorescent analysis. Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: MRG15 protein stained by MRG15 Polyclonal Antibody (Product # PA5-78349) diluted at 1:1,000. Blue: Hoechst 33342 staining.
Product Details
PA5-78349
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human MRG15. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1.83 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2736162
Product Specific Information
Positive Control: Huh7, Hep3B, mouse liver
Predicted Reactivity: Rat (100%), Zebrafish (91%), Xenopus laevis (92%), Rabbit (100%), Chicken (98%), Rhesus Monkey (100%), Bovine (99%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
MRG15 ia a component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome-DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis and DNA repair.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Esa1p-associated factor 3 homolog; MGC10631; MORF-related gene 15 protein; MORF-related gene on chromosome 15; Mortality factor 4-like protein 1; MRG15; Protein MSL3-1; testis expressed gene 189; Testis-expressed gene 189 protein; Transcription factor-like protein MRG15
Gene Aliases: Eaf3; FWP006; HSPC008; HSPC061; HsT17725; MEAF3; mKIAA4002; MORF4L1; MORFRG15; MRG15; PP368; S863-6; TEG-189; Tex189
UniProt ID: (Human) Q9UBU8, (Mouse) P60762
Entrez Gene ID: (Human) 10933, (Mouse) 21761
double-strand break repair via homologous recombination
chromatin remodeling
chromatin silencing
transcription, DNA-templated
cell proliferation
chromatin modification
histone deacetylation
regulation of growth
histone H4 acetylation
histone H2A acetylation
DNA repair
DNA recombination
regulation of transcription, DNA-templated
cellular response to DNA damage stimulus
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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