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Product Details
PA5-102263
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human MRGPRX3(Accession Q96LB0), corresponding to amino acid residues P105-I155.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2851675
Product Specific Information
Antibody detects endogenous levels of total MRGX3.
Target Information
Orphan receptor activated by a subset of RFamide-family neuropeptides such as FLRF-amide and FMRF-amide. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. May regulate the function of nociceptive neurons by modulation of pain perception. Expressed in a subset of IB4-positive small diameter nociceptive dorsal root neurons.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: G protein-coupled receptor MRGX3; G protein-coupled receptor SNSR1; G protein-coupled receptor SNSR2; Hdrr1; HDRR2; Mas-related G-protein coupled receptor member X3; mas-related GPCR member X3; MAS-related GPR, member X3; MGC108580; Sensory neuron-specific G-protein coupled receptor 1/2
Gene Aliases: GPCR; MRGPRX3; MRGX3; SNSR1; SNSR2
UniProt ID: (Human) Q96LB0
Entrez Gene ID: (Human) 117195
Performance Guarantee
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