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          • Primary Antibodies ›
          • MRP1 Antibodies

          Proteintech

          MRP1 Monoclonal Antibody (1G4A2)

          11 References
          View all (27) MRP1 antibodies

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          Cite MRP1 Monoclonal Antibody (1G4A2)

          • Antibody Testing Data (1)
          MRP1 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.
          MRP1 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          MRP1 Antibody (67228-1-IG) in WB

          Non-boil and boiled HepG2 and A549 cell lysates were subjected to SDS PAGE followed by western blot with 67228-1-Ig (ABCC1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. Left panel was exposed for 20 sec. and right panel was exposed for 1 min. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          MRP1 Antibody in Western Blot (WB)

          Product Details

          67228-1-IG

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:10,000
          View 9 publications 9 publications

          Immunohistochemistry (IHC)

          -
          View 2 publications 2 publications
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Mouse / IgG1

          Class

          Monoclonal

          Type

          Antibody

          Clone

          1G4A2

          Immunogen

          ABCC1 Fusion Protein Ag27048

          Conjugate

          Unconjugated Unconjugated Unconjugated
          • CoraLite Plus 488
          • Request custom conjugation

          Form

          Liquid

          Concentration

          1000 µg/mL

          Purification

          Protein G

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice

          Product Specific Information

          Aliquoting is unnecessary for -20°C storage.

          Target Information

          The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutathione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternative splicing by exon deletion results in several splice variants but maintains the original open reading frame in all forms.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: ATP-binding cassette sub-family C member 1; ATP-binding cassette transporter variant ABCC1delta-ex13; ATP-binding cassette transporter variant ABCC1delta-ex13&14; ATP-binding cassette transporter variant ABCC1delta-ex25; ATP-binding cassette transporter variant ABCC1delta-ex25&26; ATP-binding cassette, sub-family C (CFTR/MRP), member 1; DKFZp686N04233; DKFZp781G125; Glutathione-S-conjugate-translocating ATPase ABCC1; leuk; Leukotriene C(4) transporter; LTC4 transporter; Multidrug resistance-associated protein 1

          View more View less

          Gene Aliases: ABC29; ABCC; ABCC1; GS-X; MRP; MRP1

          View more View less

          UniProt ID: (Human) P33527

          View more View less

          Entrez Gene ID: (Human) 4363

          View more View less

          Function(s)
          transporter activity ATP binding cobalamin-transporting ATPase activity ATPase activity ATPase activity, coupled to transmembrane movement of substances anion transmembrane-transporting ATPase activity
          Process(es)
          leukotriene metabolic process transport cobalamin metabolic process cobalamin transport vitamin transmembrane transport response to drug transmembrane transport anion transmembrane transport
          It has to be done as per old AB suggested Products section.
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