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Invitrogen
MRP3 Polyclonal Antibody
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MRP3 Antibody (PA5-78258) in WB
MRP3 Polyclonal Antibody detects MRP3 protein by western blot analysis. HCT116 whole cell extracts and membrane extracts (30 µg) were separated by 5% SDS-PAGE, and the membrane was blotted with MRP3 Polyclonal Antibody (Product # PA5-78258) diluted at 1:500.
Product Details
PA5-78258
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide encompassing a sequence within the Extracellular domain of human MRP3. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1.58 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2736165
Product Specific Information
Positive Control: HCT116 whole cell extract (unboiled), HCT116 membrane fraction extract (unboiled)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ATP-binding cassette protein C3; ATP-binding cassette sub-family C member 3; ATP-binding cassette transporter; ATP-binding cassette, sub-family C (CFTR/MRP), member 3; Canalicular multispecific organic anion transporter 2; canicular multispecific organic anion transporter; DKFZp686E22157; MLP-2; MOAT-D; MRP-like protein 2; Multi-specific organic anion transporter D; multidrug resistance associated protein; multidrug resistance protein 3; Multidrug resistance-associated protein 3; organic anion transporter; transporter
Gene Aliases: 1700019L09Rik; ABC31; ABCC3; CMOAT2; EST90757; MLP2; MOAT-D; MRP3
UniProt ID: (Human) O15438, (Rat) O88563, (Mouse) B2RX12
Entrez Gene ID: (Human) 8714, (Rat) 140668, (Mouse) 76408
ATP binding
organic anion transmembrane transporter activity
bile acid-exporting ATPase activity
ATPase activity, coupled to transmembrane movement of substances
anion transmembrane-transporting ATPase activity
xenobiotic-transporting ATPase activity
drug transmembrane transporter activity
nucleotide binding
transporter activity
ATPase activity
drug transmembrane transport
metabolic process
response to organic substance
response to organonitrogen compound
response to organic cyclic compound
canalicular bile acid transport
drug transport
response to estradiol
response to lipopolysaccharide
xenobiotic transport
transmembrane transport
transport
bile acid and bile salt transport
anion transmembrane transport
organic acid transmembrane transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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