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Invitrogen
MRP4 Polyclonal Antibody
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Product Details
PA5-78695
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
E.coli-derived human MRP4 recombinant protein (Position: M1-P370).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5mg BSA
Contains
0.05mg sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2745811
Product Specific Information
Human ATF1 shares 91% amino acid (aa) sequence identity with mouse ATF1.
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - IHC: rat intestine tissue, human intestinal cancer tissue, mouse intestine tissue.
Target Information
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies. This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in cellular detoxification as a pump for its substrate, organic anions. Alternative splicing results in multiple splice variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ABC-tranporter; ATP-binding cassette protein C4; ATP-binding cassette sub-family C member 4; ATP-binding cassette subfamily C member 4; ATP-binding cassette, sub-family C (CFTR/MRP), member 4; bA464I2.1 (ATP-binding cassette, sub-family C (CFTR/MRP), member 4); canalicular multispecific organic anion transporter (ABC superfamily); EST170205; MOAT-B; MRP/cMOAT-related ABC transporter; Multi-specific organic anion transporter B; Multidrug resistance-associated protein 4; RP11-74A12.1
Gene Aliases: ABCC4; D630049P08Rik; MOAT-B; MOATB; MRP4
UniProt ID: (Human) O15439, (Rat) F1M3J4, (Mouse) E9Q236
Entrez Gene ID: (Human) 10257, (Rat) 170924, (Mouse) 239273
ATP binding
ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism
15-hydroxyprostaglandin dehydrogenase (NAD+) activity
anion transmembrane-transporting ATPase activity
molecular_function
ATPase activity, coupled to transmembrane movement of substances
drug transmembrane transporter activity
metabolic process
response to organic substance
response to organonitrogen compound
response to organic cyclic compound
response to drug
positive regulation of smooth muscle cell proliferation
transmembrane transport
platelet degranulation
biological_process
prostaglandin secretion
cilium assembly
oxidation-reduction process
anion transmembrane transport
drug transmembrane transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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