Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: GPYLISDLDQ RGRRRSFAER YDPSLKTMIP VRPCARLAPN PVDDAGLLSF ATFSWLTPVM VKGYRQRLTV DTLPPLSTYD SSDTNAKRFR V
Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 84%.
This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two ATP-binding domains and 12 transmembrane regions. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White. This gene is a member of the MRP subfamily which is involved in multi-drug resistance. This gene and another subfamily member are arranged head-to-tail on chromosome 16q12.1. Increased expression of this gene is associated with breast cancer. [provided by RefSeq, Jul 2008].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ATP-binding cassette sub-family C member 12; ATP-binding cassette transporter sub-family C member 12; ATP-binding cassette, sub-family C (CFTR/MRP), member 12; Multidrug resistance-associated protein 9
Gene Aliases: ABCC12; MRP9
UniProt ID: (Human) Q96J65
Entrez Gene ID: (Human) 94160
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