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Proteintech
MRPL28 Polyclonal Antibody
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Product Details
21604-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
MRPL28 Fusion Protein Ag16224 (1-256 aa encoded by BC000990)
Conjugate
Form
Liquid
Concentration
0.17 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MPLHKYPVW LWKRLQLREG ICSRLPGYYL RSLEEERTPT PVHYRPHGAK FKINPKNGQR ERVEDVPIPI YFPPESQRGL WGGEGWILGQ IYANNDKLSK RLKKVWKPQL FEREFYSEIL DKKFTVTVTM RTLDLIDEAY GLDFYILKTP KEDLCSKFGM DLKRGMLLRL ARQDPQLHPE DPERRAAIYD KYKEFAIPEE EAEWVGLTLE EAIEKQRLLE EKDPVPLFKI YVAELIQQLQ QQALSEPAVV QKRASGQ (1-256 aa encoded by BC000990)
Target Information
MRP-L28 (39S ribosomal protein L28, melanoma-associated antigen recognized by T lymphocytes) is a mitochondrial protein that belongs to the ribosomal protein L28P family. MRP-L28 potentially represents an important therapeutic reagent for HLA-A24 (A24) patients as this antigen is recognized by tumor-infiltrating lymphocyte (TIL) 1290, which targets the A24 serotype. HLAA24 (A24) is an HLA-A serotype that identifies the more common HLA-A24 gene products. A24 is a split antigen that is also recognized by the A9 broad antigen type and the similar A23 types. A24 is common in Austronesia and has one of the highest A allele frequencies for a number of peoples, including Papua New Guineans, indigeonous Taiwanese (eastern tribals), Yupik and Greenland Eskimos. MRP-L28 is found in a variety of normal tissues including spleen, testis, thymus, liver, kidney, brain, adrenal, lung and retinal tissue.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 39S ribosomal protein L28, mitochondrial; HGNC6756; L28mt; Large ribosomal subunit protein bL28m; MAAT 1; Melanoma antigen p15; melanoma-associated antigen recognised by cytotoxic T lymphocytes; melanoma-associated antigen recognized by T lymphocytes; Melanoma-associated antigen recognized by T-lymphocytes; MGC8499; mitochondrial ribosomal protein L28; MRP L28; MRP-L28; MRPL 28
Gene Aliases: 1110015G04Rik; L28mt; MAAT1; MRP-L28; MRPL28; p15
UniProt ID: (Human) Q13084, (Mouse) Q9D1B9
Entrez Gene ID: (Human) 10573, (Rat) 497876, (Mouse) 68611
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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