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Product Details
66531-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
1B4B4
Immunogen
MRPL45 Fusion Protein Ag8207 (86-329 aa encoded by BC006235)
Conjugate
Form
Liquid
Concentration
0.9 mg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: AGLVIPPEK SDRSIHLACT AGIFDAYVPP EGDARISSLS KEGLIERTER MKKTMASQVS IRRIKDYDAN FKIKDFPEKA KDIFIEAHLC LNNSDHDRLH TLVTEHCFPD MTWDIKYKTV RWSFVESLEP SHVVQVRCSS MMNQGNVYGQ ITVRMHTRQT LAIYDRFGRL MYGQEDVPKD VLEYVVFEKQ LTNPYGSWRM HTKIVPPWAP PKQPILKTVM IPGPQLKPEE EYEEAQGEAQ KPQLA (86-329 aa encoded by B C006235)
Target Information
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Pseudogenes corresponding to this gene are found on chromosomes 2p and 17q.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 39S ribosomal protein L45, mitochondrial; L45mt; Large ribosomal subunit protein mL45; MGC11321; MRP-L45
Gene Aliases: 2600005P05Rik; AU043542; L45mt; MRP-L45; Mrpl45; R75241
UniProt ID: (Mouse) Q9D0Q7
Entrez Gene ID: (Human) 84311, (Rat) 287656, (Mouse) 67036
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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