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Antibody detects endogenous levels of total MRPL9.
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found at 8q21.11.
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Protein Aliases: 39S ribosomal L9; 39S ribosomal protein L9, mitochondrial; L9mt; Large ribosomal subunit protein bL9m
Gene Aliases: L9mt; MRPL9
UniProt ID: (Human) Q9BYD2
Entrez Gene ID: (Human) 65005
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