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Product Details
PA5-101348
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human MRPS18C(Accession Q9Y3D5), corresponding to amino acid residues S81-K131.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2850784
Product Specific Information
Antibody detects endogenous levels of total MRPS18C.
Target Information
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S18P family. The encoded protein is one of three that has significant sequence similarity to bacterial S18 proteins. The primary sequences of the three human mitochondrial S18 proteins are no more closely related to each other than they are to the prokaryotic S18 proteins. Pseudogenes corresponding to this gene are found on chromosomes 8p, 12p, 15q, and 22q. [provided by RefSeq, Jul 2008].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 28S ribosomal protein S18-1, mitochondrial; 28S ribosomal protein S18c, mitochondrial; mitochondrial ribosomal protein S18-1; MRP-S18-1; MRP-S18-c; mrps18-c; S18mt-c; Small ribosomal subunit protein bS18c; Small ribosomal subunit protein bS18m
Gene Aliases: 1110037D14Rik; CGI-134; MRP-S18-1; MRP-S18-c; MRPS18-1; mrps18-c; MRPS18C; S18mt-c
UniProt ID: (Human) Q9Y3D5, (Mouse) Q8R2L5
Entrez Gene ID: (Human) 51023, (Rat) 289469, (Mouse) 68735
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