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Invitrogen
MRPS22 Polyclonal Antibody
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FIGURE: 1 / 1
MRPS22 Antibody (PA5-97004) in WB
Western blot analysis of MRPS22 in extracts of various cell lines. Samples were incubated with MRPS22 Polyclonal antibody (Product # PA5-97004) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
Product Details
PA5-97004
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-360 of human MRPS22 (NP_0645761)
Conjugate
Form
Liquid
Concentration
2.21 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2808806
Product Specific Information
Immunogen sequence: MAPLGTTVLL WSLLRSSPGV ERVCFRARIQ PWHGGLLQPL PCSFEMGLPR RRFSSEAAES GSPETKKPTF MDEEVQSILT KMTGLNLQKT FKPAIQELKP PTYKLMTQAQ LEEATRQAVE AAKVRLKMPP VLEERVPIND VLAEDKILEG TETTKYVFTD ISYSIPHRER FIVVREPSGT LRKASWEERD RMIQVYFPKE GRKILTPIIF KEENLRTMYS QDRHVDVLNL CFAQFEPDST EYIKVHHKTY EDIDKRGKYD LLRSTRYFGG MVWYFVNNKK IDGLLIDQIQ RDLIDDATNL VQLYHVLHPD GQSAQGAKDQ AAEGINLIKV FAKTEAQKGA YIELTLQTYQ EALSRHSAAS; Positive Samples: HepG2, HeLa, SW480, A-549, MCF-7, Jurkat; Cellular Location: Mitochondrion
Target Information
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that does not seem to have a counterpart in prokaryotic and fungal-mitochondrial ribosomes. This gene lies telomeric of and is transcribed in the opposite direction from the forkhead box L2 gene. A pseudogene corresponding to this gene is found on chromosome Xq.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 28S ribosomal protein S22, mitochondrial; MRP-S22; ribosomal protein, mitochondrial, S22; S22mt; Small ribosomal subunit protein mS22
Gene Aliases: 3100002P07Rik; C3orf5; COXPD5; GIBT; GK002; MRP-S22; MRPS22; RPMS22
UniProt ID: (Human) P82650, (Mouse) Q9CXW2
Entrez Gene ID: (Human) 56945, (Mouse) 64655, (Rat) 683519
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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