Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Product Details
16288-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
MRPS31 Fusion Protein Ag9434 (63-395 aa encoded by BC022045)
Conjugate
Form
Liquid
Concentration
0.31 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: NSVICSKKD KQSVRTEEIS KETSESQDSE KENTKKDLLG IIKGMKVELS TVNVRTTKPP KRRPLKSLEA ALGRLRRATE YAPKKRIEPL SPELVAAASA VADSLPFDKQ TTKSELLSQL QQHEEESRAQ RDAKRPKISF SNIISDMKVA RSATARVRSR PELRIQFDEG YDNYPGQEKT DDLKKRKNIF TGKRLNIFDM MAVTKEAPET DTSPSLWDVE FAKQLATVNE QPLQNGFEEL IQWTKEGKLW EFPINNEAGF DDDGSEFHEH IFLEKHLESF PKQGPIRHFM ELVTCGLSKN PYLSVKQKVE HIEWFRNYFN EKKDILKESN IQFN (63-395 aa encoded by BC022045)
Target Information
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. The 28S subunit of the mammalian mitoribosome may play a crucial and characteristic role in translation initiation. This gene encodes a 28S subunit protein that has also been associated with type 1 diabetes; however, its relationship to the etiology of this disease remains to be clarified. Pseudogenes corresponding to this gene have been found on chromosomes 3 and 13.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 28S ribosomal protein S31, mitochondrial; Imogen 38; islet mitochondrial antigen, 38 kD; MRP-S31; S31mt; Small ribosomal subunit protein mS31
Gene Aliases: 1500002D03Rik; AA960481; Imogen38; Imogen44; IMOGN38; MRP-S31; MRPS31; S31mt
UniProt ID: (Human) Q92665, (Rat) B0BN56, (Mouse) Q61733
Entrez Gene ID: (Human) 10240, (Rat) 290850, (Mouse) 57312
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support