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FIGURE: 1 / 1
Sequence of this protein is as follows: MATAVRAVGC LPVLCSGTAG HLLGRQCSLN TLPAASILAW KSVLGNGHLS SLGTRDTHPY ASLSRALQTQ CCISSPSHLM SQQYRPYSFF TKLTADELWK GALAETGAGA KKGRGKRTKK KKRKDLNRGQ IIGEGRYGFL WPGLNVPLMK NGAVQTIAQR SKEEQEKVEA DMIQQREEWD RKKKMKVKRE RGWSGNSWGG ISLGPPDPGP CGETYEDFDT RILEVRNVFT MTAKEGRKKS IRVLVAVGNG KGAAGFSIGK ATDRMDAFRK AKNRAVHHLH YIERYEDHTI FHDISLRFKR THIKMKKQPK GYGLRCHRAI ITICRLIGIK DMYAKVSGSI NMLSLTQGLF RGLSRQETHQ QLADKKGLHV VEIREECGPL PIVVASPRGP LRKDPEPEDE VPDVKLDWED VKTAQGMKRS VWSNLKRAAT
Mitochondrial ribosomes consist of a large 39S subunit and a small 28S subunit, both of which are comprised of multiple mitochondrial ribosomal proteins (MRPs) that are encoded by nuclear genes and are essential for protein synthesis within mitochondria. MRP-S5 (mitochondrial ribosomal protein S5), alternatively known as S5mt, is a 430 amino acid mitochondrial protein belonging to the ribosomal protein S5P family. A component of the 28S subunit, MRP-S5 contains one S5 DRBM domain and exists as two alternatively spliced isoforms. The gene encoding MRP-S5 maps to human chromosome 2, which consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2 including Harlequin icthyosis, sitosterolemia and Alstrom syndrome.
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Protein Aliases: 28S ribosomal protein S5, mitochondrial; mitochondrial 28S ribosomal protein S5; MRP-S5; Small ribosomal subunit protein uS5m
Gene Aliases: MRP-S5; MRPS5; S5mt
UniProt ID: (Human) P82675
Entrez Gene ID: (Human) 64969
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