Proteintech

MRRF Polyclonal Antibody

MRRF Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 3

MRRF Antibody (12357-2-AP) in ICC/IF

Immunofluorescent analysis of MCF-7 cells, using MRRF antibody 12357-2-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IGG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).

MRRF Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Product Details

12357-2-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 3 publications 3 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

1:20-1:200

Not applicable (N/A)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

MRRF Fusion Protein Ag3021 (1-262 aa encoded by BC013049)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.13 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MALGLKCFR MVHPTFRNYL AASIRPVSEV TLKTVHERQH GHRQYMAYSA VPVRHFATKK AKAKGKGQSQ TRVNINAALV EDIINLEEVN EEMKSVIEAL KDNFNKTLNI RTSPGSLDKI AVVTADGKLA LNQISQISMK SPQLILVNMA SFPECTAAAI KAIRESGMNL NPEVEGTLIR VPIPQVTREH REMLVKLAKQ NTNKAKDSLR KVRTNSMNKL KKSKDTVSED TIRLIEKQIS QMADDTVAEL DRHLAVKTKE LLG (1-262 aa encoded by BC013049)

Target Information

Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. Ota T., Nat. Genet. 36:40-45(2004). Humphray S.J., Nature 429:369-374(2004). Zhang Y., Biochim. Biophys. Acta 1443:245-250(1998).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Fluoride impairs mitochondrial translation by targeting miR-221-3p/c-Fos/RMND1 axis contributing to neurodevelopment defects.

The Science of the total environment

Li D,Zhao Q,Xie L,Wang C,Tian Z,Tang H,Xia T,Wang A

Sat Apr 15 00:00:00 UTC 2023

Non-canonical phosphoglycerate dehydrogenase activity promotes liver cancer growth via mitochondrial translation and respiratory metabolism.

The EMBO journal

Shu Y,Hao Y,Feng J,Liu H,Li ST,Feng J,Jiang Z,Ye L,Zhou Y,Sun Y,Zhou Z,Wei H,Gao P,Zhang H,Sun L

Thu Dec 01 00:00:00 UTC 2022

Muscle denervation reduces mitochondrial biogenesis and mitochondrial translation factor expression in mice.

Biochemical and biophysical research communications

Yokokawa T,Mori R,Suga T,Isaka T,Hayashi T,Fujita S

Thu Jun 18 00:00:00 UTC 2020

Exercise-induced mitochondrial biogenesis coincides with the expression of mitochondrial translation factors in murine skeletal muscle.

Physiological reports

Yokokawa T,Kido K,Suga T,Isaka T,Hayashi T,Fujita S

Mon Oct 01 00:00:00 UTC 2018

Exercise-induced mitochondrial biogenesis coincides with the expression of mitochondrial translation factors in murine skeletal muscle.

Physiological reports

Yokokawa T,Kido K,Suga T,Isaka T,Hayashi T,Fujita S

Mon Oct 01 00:00:00 UTC 2018

Bioinformatics

Protein Aliases: Ribosome-recycling factor, mitochondrial; Ribosome-releasing factor, mitochondrial; RRF

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Gene Aliases: 2400002D02Rik; MRFF; MRRF; MTRRF; RRF

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UniProt ID: (Human) Q96E11, (Mouse) Q9D6S7, (Rat) Q5RKI9

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Entrez Gene ID: (Human) 92399, (Mouse) 67871, (Rat) 311903

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Function(s)

ribosomal large subunit binding molecular_function

Process(es)

ribosome disassembly mitochondrial translational termination translation

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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MRRF Polyclonal Antibody

MRRF Antibody (12357-2-AP) in ICC/IF

Product Details

12357-2-AP

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Not applicable (N/A)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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