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Recommended positive controls: 293T, mouse muscle.
Predicted reactivity: Mouse (95%), Rat (94%), Xenopus laevis (80%), Pig (96%), Bovine (94%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes a nuclear protein and has similarity to drosophila male-specific lethal-3 gene. The drosophila protein plays a critical role in a dosage-compensation pathway, which equalizes X-linked gene expression in males and females. Thus this encoded protein is thought to play a similar function in chromatin remodeling and transcriptional regulation. This gene has been found to undergo X inactivation. There are four alternatively spliced transcript variants of this gene encoding different isoforms.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Male-specific lethal 3 homolog; Male-specific lethal-3 homolog 1; Male-specific lethal-3 protein-like 1; MSL complex subunit 3; MSL3-like 1
Gene Aliases: AU018931; MSL3; Msl31; MSL3L1
UniProt ID: (Human) Q8N5Y2, (Mouse) Q9WVG9
Entrez Gene ID: (Human) 10943, (Mouse) 17692
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