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Immunogen sequence: NPSTPQSTES QPTTGEPATP KRRKAEPEAL QSLRRSTRHS ANCDRLSESS ASPQPKRRQQ DTSASMPKLF LHLEKKTPVH SRSSSPIPLT PSKEGSAV
Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 95%.
This gene encodes a nuclear protein and has similarity to drosophila male-specific lethal-3 gene. The drosophila protein plays a critical role in a dosage-compensation pathway, which equalizes X-linked gene expression in males and females. Thus this encoded protein is thought to play a similar function in chromatin remodeling and transcriptional regulation. This gene has been found to undergo X inactivation. There are four alternatively spliced transcript variants of this gene encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Male-specific lethal 3 homolog; Male-specific lethal-3 homolog 1; Male-specific lethal-3 protein-like 1; MSL complex subunit 3; MSL3-like 1
Gene Aliases: MSL3; MSL3L1
UniProt ID: (Human) Q8N5Y2
Entrez Gene ID: (Human) 10943
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