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MSRA Antibody (MA5-50973) in IHC (P)
Immunohistochemistry (Paraffin) analysis of MSRA in Human Kidney Tissue. Samples were incubated in MSRA monoclonal antibody (Product # MA5-50973) using a dilution of 20 µg/mL followed by HRP-Linked Caprine Anti-Mouse IgG at a dilution of 2 µg/mL and DAB staining.
Product Details
MA5-50973
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Pig,
Rat
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
C6
Immunogen
Recombinant Human MSRA protein, Ala27-Lys235 (Accession #Q9UJ68)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A/G
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.05% Proclin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_3093365
Target Information
Methionine sulfoxide reductase (MsrA) reduces methionine sulfoxide (MetO) residues in proteins and free MetO to Methionine (Met). The catalytic activity of MsrA is dependent of bound metal and cofactors but it requires reducing equivalents from either DTT or a thioredoxin-regenerating system. MsrA plays an essential role in protecting cells against oxidative damage. The substrates of MsrA include calmodulin, HIV protease and a 1-proteinase-inhibitor. Recent studies indicate that there is a connection between MsrA and Alzheimer's disease in mammals.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cytosolic methionine-S-sulfoxide reductase; Mitochondrial peptide methionine sulfoxide reductase; peptide met (O) reductase; Peptide Met(O) reductase; peptide methionine sulfoxide reductase; Peptide-methionine (S)-S-oxide reductase; PMSR; Protein-methionine-S-oxide reductase
Gene Aliases: MSRA; PMSR
UniProt ID: (Human) Q9UJ68, (Rat) Q923M1
Entrez Gene ID: (Human) 4482, (Rat) 29447
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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