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MT1 Antibody (PA5-144456) in WB
Western blot analysis of MT1 in recombinant protein using a dilution of 1:2,000. Samples were incubated with MT1 polyclonal antibody (Product # PA5-144456). Secondary: Goat polyclonal to rabbit IgG at 1:50,000 dilution. Predicted band size: 12 kDa. Observed band size: 18 kDa.
Product Details
PA5-144456
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
C. elegans
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Caenorhabditis elegans MT1 protein
Conjugate
Form
Liquid
Concentration
4.5 mg/mL
Purification
Protein A/G
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.03% Proclin 300
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_3092388
Target Information
This gene is a member of the metallothionein family of genes. Proteins encoded by this gene family are low in molecular weight, are cysteine-rich, lack aromatic residues, and bind divalent heavy metal ions. The conserved cysteine residues co-ordinate metal ions using mercaptide linkages. These proteins act as anti-oxidants, protect against hydroxyl free radicals, are important in homeostatic control of metal in the cell, and play a role in detoxification of heavy metals. Disruption of two metallothionein genes in mouse resulted in defects in protection against heavy metals, oxidative stress, immune reactions, carcinogens, and displayed obesity. MT1A (Metallothionein 1A) is a Protein Coding gene. Diseases associated with MT1A include Menkes Disease and Deficiency Anemia. Among its related pathways are Metal ion SLC transporters and Cellular responses to stimuli. An important paralog of this gene is MT2A.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Metallothionein; Metallothionein-1; Metallothionein-I; MT-1; MT-I
Gene Aliases: K11G9.6; met-1; mtl-1
UniProt ID: (C. elegans) P17511
Entrez Gene ID: (C. elegans) 179060
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