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Invitrogen
MT2A Polyclonal Antibody
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MT2A Antibody (PA5-102549) in IHC (P)
Immunohistochemistry analysis of MT2A in mouse stomach tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with MT2A polyclonal antibody (Product # PA5-102549) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Product Details
PA5-102549
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human MT2A(Accession P02795), corresponding to amino acid residues S32-A61.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2851951
Product Specific Information
Antibody detects endogenous levels of total MT2A.
Target Information
Metallothionein (MT) is a sulfhydryl- and cysteine-rich protein found in microorganisms, plants and all invertebrate and vertebrate animals. Metallothioneins are a group of ubiquitous low-molecular-weight proteins that have functional roles in cell growth, repair and differentiation. They are implicated primarily in metal ion detoxification, in that they are essential for the protection of cells against the toxicity of cadmium, mercury and copper. Metallothionein, as an acute phase or stress-response protein and free radical scavenger, is related to inflammation and cellular protection from reactive forms of oxygen, ionizing radiation, pharmacological agents and mutagens. Metallothioneins are known to be broadly expressed in heart, liver, kidney, breast and testis tissue.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Metallothionein; Metallothionein 2; metallothionein 2A; Metallothionein-2; Metallothionein-2A; Metallothionein-II; MT-2; MT-II
Gene Aliases: CES1; MT2; MT2A
UniProt ID: (Human) P02795, (Rat) P04355
Entrez Gene ID: (Human) 4502, (Rat) 689415
cellular copper ion homeostasis
response to metal ion
cellular response to drug
cellular response to interleukin-3
cellular response to erythropoietin
negative regulation of growth
interferon-gamma-mediated signaling pathway
cellular response to zinc ion
cellular zinc ion homeostasis
nitric oxide mediated signal transduction
detoxification of copper ion
astrocyte activation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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