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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • MTCH2 Antibodies

          Proteintech

          MTCH2 Polyclonal Antibody

          12 References
          View all (8) MTCH2 antibodies

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          Datasheet
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          Datasheet
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          Cite MTCH2 Polyclonal Antibody

          • Antibody Testing Data (8)
          MTCH2 Antibody in Immunocytochemistry (ICC/IF)
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          MTCH2 Antibody in Immunocytochemistry (ICC/IF)
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          FIGURE: 1 / 8

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          MTCH2 Antibody (16888-1-AP) in ICC/IF

          Immunofluorescent analysis of NIH/3T3 cells using 16888-1-AP (MTCH2 antibody) at dilution of 1:25 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG (H+L). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          MTCH2 Antibody in Immunocytochemistry (ICC/IF)
          MTCH2 Antibody in Immunocytochemistry (ICC/IF)
          MTCH2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          MTCH2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          MTCH2 Antibody in Western Blot (WB)
          MTCH2 Antibody in Western Blot (WB)
          MTCH2 Antibody in Western Blot (WB)
          MTCH2 Antibody in Immunoprecipitation (IP)

          Product Details

          16888-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:3,000
          View 9 publications 9 publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:20-1:200
          -

          Immunocytochemistry (ICC/IF)

          1:10-1:100
          View 2 publications 2 publications

          Immunoprecipitation (IP)

          0.5-4.0 µg
          View 1 publication 1 publication
          Product Specifications

          Species Reactivity

          Human

          Published species

          Human, Mouse, Pig

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          MTCH2 Fusion Protein Ag10399 (31-178 aa encoded by BC000875)
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.24 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Product Specific Information

          Immunogen sequence: GYEPLPPTI GRNIFGRQVC QLPGLFSYAQ HIASIDGRRG LFTGLTPRLC SGVLGTVVHG KVLQHYQESD KGEELGPGNV QKEVSSSFDH VIKETTREMI ARSAATLITH PFHVITLRSM VQFIGRESKY CGLCDSIITI YREEGILGF (31-178 aa encoded by BC000875)

          Target Information

          MTCH2 is a member of the mitochondrial carrier protein family that catalyze the exchange of substrates across the inner mitochondrial membrane and is targeted by Bid, a pro-apoptotic Bcl-2 family member, in response to apoptotic signals, suggesting that MTCH2 may play a key role in the mitochondrial apoptosis pathway. Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: 2310034D24Rik; Met-induced mitochondrial protein; Mitochondrial carrier homolog 2; solute carrier family 25, member 50

          View more View less

          Gene Aliases: HSPC032; MIMP; MTCH2; SLC25A50

          View more View less

          UniProt ID: (Human) Q9Y6C9

          View more View less

          Entrez Gene ID: (Human) 23788

          View more View less

          Process(es)
          positive regulation of apoptotic process protein localization to mitochondrion hepatocyte apoptotic process regulation of mitochondrial membrane permeability involved in apoptotic process
          It has to be done as per old AB suggested Products section.
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