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Invitrogen
MTCH2 Polyclonal Antibody
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MTCH2 Antibody (PA5-25406) in IHC (P)
Immunohistochemistry analysis of MTCH2 in formalin fixed and paraffin embedded human brain tissue. Samples were incubated with MTCH2 polyclonal antibody (Product # PA5-25406) followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of this antibody for immunohistochemistry. Clinical relevance has not been evaluated.
Product Details
PA5-25406
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 75-103 amino acids from the N-terminal region of human MTCH2
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2542906
Target Information
MTCH2 is a member of the mitochondrial carrier protein family that catalyze the exchange of substrates across the inner mitochondrial membrane and is targeted by Bid, a pro-apoptotic Bcl-2 family member, in response to apoptotic signals, suggesting that MTCH2 may play a key role in the mitochondrial apoptosis pathway. Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 2310034D24Rik; Met-induced mitochondrial protein; Mitochondrial carrier homolog 2; solute carrier family 25, member 50
Gene Aliases: 2310034D24Rik; 4930539J07Rik; HSPC032; MIMP; MTCH2; SLC25A50
UniProt ID: (Human) Q9Y6C9, (Mouse) Q791V5
Entrez Gene ID: (Human) 23788, (Mouse) 56428
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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