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Transcription termination factor. Binds to a 28 bp region within the tRNA(Leu(uur)) gene at a position immediately adjacent to and downstream of the 16S rRNA gene; this region comprises a tridecamer sequence critical for directing accurate termination. Binds DNA along the major grove and promotes DNA bending and partial unwinding. Promotes base flipping. Transcription termination activity appears to be polarized with highest specificity for transcripts initiated on the light strand.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Mitochondrial transcription termination factor 1; Mitochondrial transcription termination factor 1a; mitochondrial transcription termination factor 1b; mTERF; mTERF1a; mterf1b; Transcription termination factor 1, mitochondrial; Transcription termination factor 1a, mitochondrial; transcription termination factor, mitochondrial
Gene Aliases: 4931431L11Rik; 9230106K09Rik; MTERF; MTERF1; Mterf1a; mTERF1b
UniProt ID: (Human) Q99551, (Rat) Q9EPI8, (Mouse) Q8CHZ9
Entrez Gene ID: (Human) 7978, (Rat) 85261, (Mouse) 545725
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