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Product Details
PA5-68898
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
synthetic peptide directed towards the middle region of mouse MTGR1
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2689260
Product Specific Information
This target displays homology in the following species: Cow: 86%; Dog: 79%; Guinea Pig: 93%; Horse: 86%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%
Target Information
Myeloid tumor related gene (MTGR1) is found deleted in acute myeloid leukemia. Overexpression of MTGR1 can stimulate AML1-MTG8 to induce GCSF- dependent proliferation of L-G cells and to interfere with AML1- dependent transcription. AML1/MTG8 functions as a complex with MTGR1 and that the complex might be important in promoting leukemogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CBFA2T2 identified gene homolog; core-binding factor runt domain alpha subunit 2 translocated to 2 homolog; core-binding factor, runt domain, alpha subunit 2, translocated to, 2 homolog; DKFZp313F2116; MTG8-like protein; MTG8-related protein 1; Protein CBFA2T2; RP5-1137F22.1; ZMYND3 CBFA2T2
Gene Aliases: A430091M07; C330013D05Rik; Cbfa2t2; Cbfa2t2h; MTGR1
UniProt ID: (Mouse) O70374
Entrez Gene ID: (Mouse) 12396
regulation of transcription, DNA-templated
positive regulation of neuron projection development
epithelial cell differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
negative regulation of nucleic acid-templated transcription
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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