Proteintech

MTIF3 Polyclonal Antibody

MTIF3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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MTIF3 Antibody (14219-1-AP) in IHC (P)

Immunohistochemical analysis of paraffin-embedded human liver tissue slide using (Product # 14219-1-AP) (MTIF3 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

MTIF3 Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

14219-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:3,000

View 5 publications 5 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunoprecipitation (IP)

0.5-4.0 µg

Miscellaneous PubMed (MISC)

View 1 publication 1 publication

Not applicable (N/A)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

MTIF3 Fusion Protein Ag5457 (1-278 aa encoded by BC046166)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.29 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MAALFLKRL TLQTVKSENS CIRCFGKHIL QKTAPAQLSP IASAPRLSFL IHAKAFSTAE DTQNEGKKIK KNKTAFSNVG RKISQRVIHL FDEKGNDLGN MHRANVIRLM DERDLRLVQR NTSTEPAEYQ LMTGLQILQE RQRLREMEKA NPKTGPTLRK ELILSSNIGQ HDLDTKTKQI QQWIKKKHLV QITIKKGKNV DVSENEMEEI FHQILQTMPG IATFSSRPQA VQGGKALMCV LRALSKNEEK AYKETQETQE RDTLNKDHGN DKESNVLHQ (1-278 aa encoded by BC046166 )

Target Information

This gene encodes a translation initiation factor that is involved in mitochondrial protein synthesis. Polymorphism in this gene is associated with the onset of Parkinson's disease. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 5.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Fluoride impairs mitochondrial translation by targeting miR-221-3p/c-Fos/RMND1 axis contributing to neurodevelopment defects.

The Science of the total environment

Li D,Zhao Q,Xie L,Wang C,Tian Z,Tang H,Xia T,Wang A

Sat Apr 15 00:00:00 UTC 2023

Identification of a weight loss-associated causal eQTL in MTIF3 and the effects of MTIF3 deficiency on human adipocyte function.

eLife

Huang M,Coral D,Ardalani H,Spegel P,Saadat A,Claussnitzer M,Mulder H,Franks PW,Kalamajski S

Mon Mar 06 00:00:00 UTC 2023

Initiation Factor 3 is Dispensable For Mitochondrial Translation in Cultured Human Cells.

Scientific reports

Chicherin IV,Baleva MV,Levitskii SA,Dashinimaev EB,Krasheninnikov IA,Kamenski P

Tue Apr 28 00:00:00 UTC 2020

Stress signaling and cellular proliferation reverse the effects of mitochondrial mistranslation.

The EMBO journal

Ferreira N,Perks KL,Rossetti G,Rudler DL,Hughes LA,Ermer JA,Scott LH,Kuznetsova I,Richman TR,Narayana VK,Abudulai LN,Shearwood AJ,Cserne Szappanos H,Tull D,Yeoh GC,Hool LC,Filipovska A,Rackham O

Mon Dec 16 00:00:00 UTC 2019

Fidelity of translation initiation is required for coordinated respiratory complex assembly.

Science advances

Rudler DL,Hughes LA,Perks KL,Richman TR,Kuznetsova I,Ermer JA,Abudulai LN,Shearwood AJ,Viola HM,Hool LC,Siira SJ,Rackham O,Filipovska A

Sun Dec 01 00:00:00 UTC 2019

Novel minor HLA DR associated antigens in type 1 diabetes.

Clinical immunology (Orlando, Fla.)

Müller D,Telieps T,Eugster A,Weinzierl C,Jolink M,Ziegler AG,Bonifacio E

Sat Sep 01 00:00:00 UTC 2018

Novel minor HLA DR associated antigens in type 1 diabetes.

Clinical immunology (Orlando, Fla.)

Müller D,Telieps T,Eugster A,Weinzierl C,Jolink M,Ziegler AG,Bonifacio E

Sat Sep 01 00:00:00 UTC 2018

Bioinformatics

Protein Aliases: IF-3(Mt); IF-3Mt; IF3(mt); IF3mt; Translation initiation factor IF-3, mitochondrial

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Gene Aliases: 2810012L14Rik; AI414549; DC38; IF3mt; MTIF3

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UniProt ID: (Human) Q9H2K0, (Mouse) Q9CZD5

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Entrez Gene ID: (Human) 219402, (Mouse) 76366

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Function(s)

translation initiation factor activity protein binding translation factor activity, RNA binding ribosome binding ribosomal small subunit binding

Process(es)

translation translational initiation ribosome disassembly mitochondrial translational initiation

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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MTIF3 Polyclonal Antibody

MTIF3 Antibody (14219-1-AP) in IHC (P)

Product Details

14219-1-AP

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

Immunoprecipitation (IP)

Miscellaneous PubMed (MISC)

Not applicable (N/A)

Species Reactivity

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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