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Invitrogen
MUC5AC Monoclonal Antibody (2-12M1)
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Product Details
MA1-35705
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Bovine,
Cat,
Human,
Mouse,
Non-human primate
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
2-12M1
Immunogen
Mucin isolated from ovarian cyst fluid.
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
purified
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_1076990
Product Specific Information
2-12M1 recognizes the peptide core of gastric mucin M1/MUC5AC, and more specifically with the ‘c’ epitope amongst the a, b, c, d, e, f, g, and h protein core epitopes defined by Bara for M1. 2-12M1 and 45M1 both specifically react with epitopes located in the Cterminal cysteine rich part of the peptide core of gastric mucin (MUC5AC). MUC5AC is present in primary ovarian mucinous cancer and gastric cancer, but usually absent in colorectal adenocarcinoma, thus showing an expression pattern opposite to MUC2. AntiMUC5AC may be useful for differential identification of primary mucinous ovarian tumors from colon adenocarcinoma metastatic to the ovary. MUC5AC antibodies may also be useful for identification pancreatic carcinoma and pre-cancerous changes vs. normal pancreas.
Target Information
The antibody 2-25LE reacts with Lewisb blood group antigen, a carbohydrate determinant carried on both glycolipids and glycoproteins, detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Gastric mucin; lewis B blood group antigen; Major airway glycoprotein; MUC-5AC; mucin 5, subtypes A and C, tracheobronchial/gastric; mucin 5ac; mucin 5AC, oligomeric mucus/gel-forming pseudogene; Mucin-5 subtype AC, tracheobronchial; Mucin-5AC; TBM; Tracheobronchial mucin
Gene Aliases: 2210005L13Rik; leB; MGM; MUC5; MUC5AC; mucin; TBM
UniProt ID: (Human) P98088
Entrez Gene ID: (Human) 4586, (Mouse) 17833
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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