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Invitrogen
MUS81 Polyclonal Antibody
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Product Details
PA5-63743
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human MUS81. Recombinant protein control fragment (Product #RP-89866).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2644314
Product Specific Information
Immunogen sequence: LVEEHGSVHN LSLPESTLLQ AVTNTQVIDG FFVKRTADIK ESAAYLALLT RGLQRLYQGH TLRSRPWGTP GNPESGAMTS PNPLCSLLTF SDFNAGAIKN KAQSVREVFA RQLMQVRGVS GEKAAALVDR YSTPA
Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 89%.
Target Information
Interacts with EME1 and EME2 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication forks.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Crossover junction endonuclease MUS81; FLJ21012; FLJ44872 MUS81; MUS81 endonuclease homolog; SLX3 structure-specific endonuclease subunit homolog
Gene Aliases: MUS81; SLX3
UniProt ID: (Human) Q96NY9
Entrez Gene ID: (Human) 80198
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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