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Proteintech
MVK Polyclonal Antibody
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Product Details
12228-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
MVK Fusion Protein Ag2865 (1-396 aa encoded by BC016140)
Conjugate
Form
Liquid
Concentration
0.33 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MLSEVLLVS APGKVILHGE HAVVHGKVAL AVSLNLRTFL RLQPHSNGKV DLSLPNIGIK RAWDVARLQS LDTSFLEQGD VTTPTSEQVE KLKEVAGLPD DCAVTERLAV LAFLYLYLSI CRKQRALPSL DIVVWSELPP GAGLGSSAAY SVCLAAALLT VCEEIPNPLK DGDCVNRWTK EDLELINKWA FQGERMIHGN PSGVDNAVST WGGALRYHQG KISSLKRSPA LQILLTNTKV PRNTRALVAG VRNRLLKFPE IVAPLLTSID AISLECERVL GEMGEAPAPE QYLVLEELID MNQHHLNALG VGHASLDQLC QVTRARGLHS KLTGAGGGGC GITLLKPGLE QPEVEATKQA LTSCGFDCLE TSIGAPGVSI HSATSLDSRV QQALDGL (1-396 aa encoded by BC016140)
Target Information
Mevalonate kinase (MVK) is an early enzyme in isoprenoid and sterol synthesis. Mevalonate kinase catalyzes the ATP-dependent phosphorylation of mevalonic acid to form mevalonate 5-phosphate. Deficiency in MVK activity contributes to mevalonic aciduria and hyperimmunoglobulinemia D/periodic fever syndrome (HIDS).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: KIME; LH receptor mRNA-binding protein; LHR mRNA binding protein; Mevalonate kinase; mevalonate kinase 1; MK
Gene Aliases: 2310010A05Rik; AI256848; AI414037; LRBP; MK; MVK; MVLK; POROK3
UniProt ID: (Human) Q03426, (Mouse) Q9R008, (Rat) P17256
Entrez Gene ID: (Human) 4598, (Mouse) 17855, (Rat) 81727
cholesterol biosynthetic process
isoprenoid metabolic process
isoprenoid biosynthetic process
sterol metabolic process
phosphorylation
negative regulation of translation
isopentenyl diphosphate biosynthetic process, mevalonate pathway
regulation of cholesterol biosynthetic process
negative regulation of inflammatory response
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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