Product References
Curcumin targets miR-134-5p to suppress the progression of colorectal cancer through regulating the CDCA3/CDK1 pathway.
Naunyn-Schmiedeberg's archives of pharmacology
Liu F,Zhu C,Ma H,Yang Q
Mon Jan 01 00:00:00 UTC 2024
Curcumin targets miR-134-5p to suppress the progression of colorectal cancer through regulating the CDCA3/CDK1 pathway.
Naunyn-Schmiedeberg's archives of pharmacology
Liu F,Zhu C,Ma H,Yang Q
Mon Jan 01 00:00:00 UTC 2024
TRIM44 aggravates cardiac fibrosis after myocardial infarction via TAK1 stabilization.
Cellular signalling
Qian H,Lu Z,Hao C,Zhao Y,Bo X,Hu Y,Zhang Y,Yao Y,Ma G,Chen L
Fri Sep 01 00:00:00 UTC 2023
A new acid isolated from V. negundo L. inhibits NLRP3 inflammasome activation and protects against inflammatory diseases.
Frontiers in immunology
Di Q,Zhao X,Lin J,Li X,Li X,Tang H,Zhang R,Xiao W,Chen W
Tue May 09 00:00:00 UTC 2023
Symmetric control of sister chromatid cohesion establishment.
Nucleic acids research
Zhang J,Li L,Miao Y,Liu X,Sun H,Jiang M,Li X,Li Z,Liu C,Liu B,Xu X,Cao Q,Hou W,Chen C,Lou H
Fri Jun 09 00:00:00 UTC 2023
LZTFL1 inhibits kidney tumor cell growth by destabilizing AKT through ZNRF1-mediated ubiquitin proteosome pathway.
Oncogene
Lu J,Fu LM,Cao Y,Fang Y,Cao JZ,Pan YH,Cen JJ,Liang YP,Chen ZH,Wei JH,Huang Y,Mumin MA,Xu QH,Wang YH,Zhu JQ,Liang H,Wang Z,Deng Q,Chen W,Jin XH,Liu ZP,Luo JH
Mon May 01 00:00:00 UTC 2023
LZTFL1 inhibits kidney tumor cell growth by destabilizing AKT through ZNRF1-mediated ubiquitin proteosome pathway.
Oncogene
Lu J,Fu LM,Cao Y,Fang Y,Cao JZ,Pan YH,Cen JJ,Liang YP,Chen ZH,Wei JH,Huang Y,Mumin MA,Xu QH,Wang YH,Zhu JQ,Liang H,Wang Z,Deng Q,Chen W,Jin XH,Liu ZP,Luo JH
Mon May 01 00:00:00 UTC 2023
TRIM5α recruits HDAC1 to p50 and Sp1 and promotes H3K9 deacetylation at the HIV-1 LTR.
Nature communications
Ran XH,Zhu JW,Ni RZ,Zheng YT,Chen YY,Zheng WH,Mu D
Thu Jun 08 00:00:00 UTC 2023
TRIM5α recruits HDAC1 to p50 and Sp1 and promotes H3K9 deacetylation at the HIV-1 LTR.
Nature communications
Ran XH,Zhu JW,Ni RZ,Zheng YT,Chen YY,Zheng WH,Mu D
Thu Jun 08 00:00:00 UTC 2023
PSMD4 drives progression of hepatocellular carcinoma via Akt/COX2 pathway and p53 inhibition.
Human cell
Zhang J,Fang S,Rong F,Jia M,Wang Y,Cui H,Hao P
Fri Sep 01 00:00:00 UTC 2023
EphA2 is a functional entry receptor for HCMV infection of glioblastoma cells.
PLoS pathogens
Dong XD,Li Y,Li Y,Sun C,Liu SX,Duan H,Cui R,Zhong Q,Mou YG,Wen L,Yang B,Zeng MS,Luo MH,Zhang H
Mon May 01 00:00:00 UTC 2023
EphA2 is a functional entry receptor for HCMV infection of glioblastoma cells.
PLoS pathogens
Dong XD,Li Y,Li Y,Sun C,Liu SX,Duan H,Cui R,Zhong Q,Mou YG,Wen L,Yang B,Zeng MS,Luo MH,Zhang H
Mon May 01 00:00:00 UTC 2023
FAM210A Regulates Mitochondrial Translation and Maintains Cardiac Mitochondrial Homeostasis.
bioRxiv : the preprint server for biology
Wu J,Subbaiah KCV,Hedaya O,Chen S,Munger J,Tang WHW,Yan C,Yao P
Mon May 22 00:00:00 UTC 2023
Cofilin promotes tau pathology in Alzheimer's disease.
Cell reports
Yan M,Tang L,Dai L,Lei C,Xiong M,Zhang X,He M,Tian Y,Xiong J,Ke W,Zhang Z,Zhang C,Deng X,Zhang Z
Tue Feb 28 00:00:00 UTC 2023
TRIM21 promotes ubiquitination of SARS-CoV-2 nucleocapsid protein to regulate innate immunity.
Journal of medical virology
Mao S,Cai X,Niu S,Wei J,Jiang N,Deng H,Wang W,Zhang J,Shen S,Ma Y,Wu X,Peng Q,Huang A,Wang D
Sat Apr 01 00:00:00 UTC 2023
TRIM21 promotes ubiquitination of SARS-CoV-2 nucleocapsid protein to regulate innate immunity.
Journal of medical virology
Mao S,Cai X,Niu S,Wei J,Jiang N,Deng H,Wang W,Zhang J,Shen S,Ma Y,Wu X,Peng Q,Huang A,Wang D
Sat Apr 01 00:00:00 UTC 2023
Mitochondrial Glycerol-3-Phosphate Dehydrogenase Restricts HBV Replication via the TRIM28-Mediated Degradation of HBx.
Journal of virology
Liu C,Zhao K,Chen Y,Yao Y,Tang J,Wang J,Xu C,Yang Q,Zheng Y,Yuan Y,Sun H,Zhang Y,Zhou Y,Chen J,Wang Y,Wu C,Pei R,Chen X
Wed May 31 00:00:00 UTC 2023
Enhanced liquidity of p62 droplets mediated by Smurf1 links Nrf2 activation and autophagy.
Cell & bioscience
Xia Q,Li Y,Xu W,Wu C,Zheng H,Liu L,Dong L
Tue Feb 21 00:00:00 UTC 2023
TPM2 attenuates progression of prostate cancer by blocking PDLIM7-mediated nuclear translocation of YAP1.
Cell & bioscience
Wu Z,Ge L,Ma L,Lu M,Song Y,Deng S,Duan P,Du T,Wu Y,Zhang Z,Zhang S
Thu Feb 23 00:00:00 UTC 2023
p120-catenin promotes innate antiviral immunity through stabilizing TBK1-IRF3 complex.
Molecular immunology
Wu H,Yan X,Zhao L,Li X,Li X,Zhang Y,Gu C,Yang F,Yan J,Lou Y,Li Y,Yang L,Qin X,Wang Y
Mon May 01 00:00:00 UTC 2023
9-Butyl-Harmol Exerts Antiviral Activity against Newcastle Disease Virus through Targeting GSK-3β and HSP90β.
Journal of virology
Wang C,Wang T,Hu R,Duan L,Hou Q,Han Y,Dai J,Wang W,Ren S,Liu H,Wang X,Xiao S,Li N,Wang J,Yang Z
Thu Mar 30 00:00:00 UTC 2023
HBV X Protein Induces Degradation of UBXN7, a Novel Negative Regulator of NF-κB Signaling, to Promote HBV Replication.
Cellular and molecular gastroenterology and hepatology
Yuan S,Xu J,Wang M,Huang J,Ma S,Liu Y,Ke Y,Zeng X,Wu K,Wang J,Tian X,Zheng D,Yousaf T,Naz W,Sun J,Chen L,Guo D,Guo M,Sun G
Tue Dec 27 00:00:00 UTC 2022
HBV X Protein Induces Degradation of UBXN7, a Novel Negative Regulator of NF-κB Signaling, to Promote HBV Replication.
Cellular and molecular gastroenterology and hepatology
Yuan S,Xu J,Wang M,Huang J,Ma S,Liu Y,Ke Y,Zeng X,Wu K,Wang J,Tian X,Zheng D,Yousaf T,Naz W,Sun J,Chen L,Guo D,Guo M,Sun G
Tue Dec 27 00:00:00 UTC 2022
LIM domain-containing protein Ajuba inhibits chemotherapy-induced apoptosis by negatively regulating p53 stability in colorectal cancer cells.
Molecular oncology
Xu B,Li Q,Zhang J,Chen F
Tue Aug 01 00:00:00 UTC 2023
Lipid phosphatase SAC1 suppresses hepatitis B virus replication through promoting autophagic degradation of virions.
Antiviral research
Zheng J,Deng Y,Wei Z,Zou H,Wen X,Cai J,Zhang S,Jia B,Lu M,Lu K,Lin Y
Mon May 01 00:00:00 UTC 2023
p38-mediated FOXN3 phosphorylation modulates lung inflammation and injury through the NF-κB signaling pathway.
Nucleic acids research
Zhu X,Huang B,Zhao F,Lian J,He L,Zhang Y,Ji L,Zhang J,Yan X,Zeng T,Ma C,Liang Y,Zhang C,Lin J
Tue Mar 21 00:00:00 UTC 2023
p38-mediated FOXN3 phosphorylation modulates lung inflammation and injury through the NF-κB signaling pathway.
Nucleic acids research
Zhu X,Huang B,Zhao F,Lian J,He L,Zhang Y,Ji L,Zhang J,Yan X,Zeng T,Ma C,Liang Y,Zhang C,Lin J
Tue Mar 21 00:00:00 UTC 2023
Tea domain transcription factor TEAD4 mitigates TGF-β signaling and hepatocellular carcinoma progression independently of YAP.
Journal of molecular cell biology
Luo W,Li Y,Zeng Y,Li Y,Cheng M,Zhang C,Li F,Wu Y,Huang C,Yang X,Kremerskothen J,Zhang J,Zhang C,Tu S,Li Z,Luo Z,Lin Z,Yan X
Tue Jun 13 00:00:00 UTC 2023
The Mediator complex subunit MED25 interacts with HDA9 and PIF4 to regulate thermomorphogenesis.
Plant physiology
Shapulatov U,van Zanten M,van Hoogdalem M,Meisenburg M,van Hall A,Kappers I,Fasano C,Facella P,Loh CC,Perrella G,van der Krol A
Tue May 02 00:00:00 UTC 2023
TRIM28 negatively regulates the RLR signaling pathway by targeting MAVS for degradation via K48-linked polyubiquitination.
The Journal of biological chemistry
Chen YY,Ran XH,Ni RZ,Mu D
Mon May 01 00:00:00 UTC 2023
Recognition of an Ala-rich C-degron by the E3 ligase Pirh2.
Nature communications
Wang X,Li Y,Yan X,Yang Q,Zhang B,Zhang Y,Yuan X,Jiang C,Chen D,Liu Q,Liu T,Mi W,Yu Y,Dong C
Sat Apr 29 00:00:00 UTC 2023
HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.
Cellular and molecular gastroenterology and hepatology
Yuan J,Lv T,Yang J,Wu Z,Yan L,Yang J,Shi Y,Jiang L
Thu Jan 26 00:00:00 UTC 2023
Gasdermin D licenses MHCII induction to maintain food tolerance in small intestine.
Cell
He K,Wan T,Wang D,Hu J,Zhou T,Tao W,Wei Z,Lu Q,Zhou R,Tian Z,Flavell RA,Zhu S
Thu Jul 06 00:00:00 UTC 2023
Influence of RRM, RGG and Potential Phosphorylated Sites in Cold-Inducible Protein RBM3 on its Subcellular Localization and Neuroprotective Effects.
Frontiers in bioscience (Landmark edition)
Wang L,Shao TC,Wang CY,Li JJ,Jian SQ,Wang D,Cheng BF
Wed Feb 08 00:00:00 UTC 2023
Influence of RRM, RGG and Potential Phosphorylated Sites in Cold-Inducible Protein RBM3 on its Subcellular Localization and Neuroprotective Effects.
Frontiers in bioscience (Landmark edition)
Wang L,Shao TC,Wang CY,Li JJ,Jian SQ,Wang D,Cheng BF
Wed Feb 08 00:00:00 UTC 2023
GTPase splice variants RAC1 and RAC1B display isoform-specific differences in localization, prenylation, and interaction with the chaperone protein SmgGDS.
The Journal of biological chemistry
Koehn OJ,Lorimer E,Unger B,Harris R,Das AS,Suazo KF,Auger SA,Distefano MD,Prokop JW,Williams CL
Thu Jun 01 00:00:00 UTC 2023
GTPase splice variants RAC1 and RAC1B display isoform-specific differences in localization, prenylation, and interaction with the chaperone protein SmgGDS.
The Journal of biological chemistry
Koehn OJ,Lorimer E,Unger B,Harris R,Das AS,Suazo KF,Auger SA,Distefano MD,Prokop JW,Williams CL
Thu Jun 01 00:00:00 UTC 2023
SENP3-mediated deSUMOylation of c-Jun facilitates microglia-induced neuroinflammation after cerebral ischemia and reperfusion injury.
iScience
Xia Q,Mao M,Zhan G,Luo Z,Zhao Y,Li X
Fri Jun 16 00:00:00 UTC 2023
17β-estradiol plays the anti-osteoporosis role via a novel ESR1-Keap1-Nrf2 axis-mediated stress response activation and Tmem119 upregulation.
Free radical biology & medicine
Yang R,Li J,Zhang J,Xue Q,Qin R,Wang R,Goltzman D,Miao D
Wed Feb 01 00:00:00 UTC 2023
17β-estradiol plays the anti-osteoporosis role via a novel ESR1-Keap1-Nrf2 axis-mediated stress response activation and Tmem119 upregulation.
Free radical biology & medicine
Yang R,Li J,Zhang J,Xue Q,Qin R,Wang R,Goltzman D,Miao D
Wed Feb 01 00:00:00 UTC 2023
Radiation induces IRAK1 expression to promote radioresistance by suppressing autophagic cell death via decreasing the ubiquitination of PRDX1 in glioma cells.
Cell death & disease
Li J,Sun Y,Zhao X,Ma Y,Xie Y,Liu S,Hui B,Shi X,Sun X,Zhang X
Sat Apr 08 00:00:00 UTC 2023
Bacterial delivery of therapeutic proteins to the nuclei of cancer cells.
Biotechnology and bioengineering
Bloom SMK,O'Hare N,Forbes NS
Mon May 01 00:00:00 UTC 2023
Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis.
Cell reports
Tang Y,Yang LJ,Liu H,Song YJ,Yang QQ,Liu Y,Qian SW,Tang QQ
Tue Jan 31 00:00:00 UTC 2023
Inositol polyphosphates-regulated polyubiquitination of PHR1 by NLA E3 ligase during phosphate starvation response in Arabidopsis.
The New phytologist
Park SH,Jeong JS,Huang CH,Park BS,Chua NH
Wed Feb 01 00:00:00 UTC 2023
Inositol polyphosphates-regulated polyubiquitination of PHR1 by NLA E3 ligase during phosphate starvation response in Arabidopsis.
The New phytologist
Park SH,Jeong JS,Huang CH,Park BS,Chua NH
Wed Feb 01 00:00:00 UTC 2023
Extracellular vesicle-transmitted miR-671-5p alleviates lung inflammation and injury by regulating the AAK1/NF-κB axis.
Molecular therapy : the journal of the American Society of Gene Therapy
Lian J,Zhu X,Du J,Huang B,Zhao F,Ma C,Guo R,Zhang Y,Ji L,Yahaya BH,Lin J
Wed May 03 00:00:00 UTC 2023
Human Cytomegalovirus IE1 Impairs Neuronal Migration by Downregulating Connexin 43.
Journal of virology
Huang SN,Pan YT,Zhou YP,Wang XZ,Mei MJ,Yang B,Li D,Zeng WB,Cheng S,Sun JY,Cheng H,Zhao F,Luo MH
Wed May 31 00:00:00 UTC 2023
USP22 suppresses the NLRP3 inflammasome by degrading NLRP3 via ATG5-dependent autophagy.
Autophagy
Di Q,Zhao X,Tang H,Li X,Xiao Y,Wu H,Wu Z,Quan J,Chen W
Wed Mar 01 00:00:00 UTC 2023
USP22 suppresses the NLRP3 inflammasome by degrading NLRP3 via ATG5-dependent autophagy.
Autophagy
Di Q,Zhao X,Tang H,Li X,Xiao Y,Wu H,Wu Z,Quan J,Chen W
Wed Mar 01 00:00:00 UTC 2023
A novel RIPK1 inhibitor reduces GVHD in mice via a nonimmunosuppressive mechanism that restores intestinal homeostasis.
Blood
Yu X,Ma H,Li B,Ji Y,Du Y,Liu S,Li Z,Hao Y,Tian S,Zhao C,Du Q,Jin Z,Zhu X,Tian Y,Chen X,Sun X,Yang C,Zhu F,Ju J,Zheng Y,Zhang W,Wang J,Yang T,Wang X,Li J,Xu X,Du S,Lu H,Ma F,Zhang H,Zhang Y,Zhang X,Hu S,He S
Thu Mar 02 00:00:00 UTC 2023
TRAF3 activates STING-mediated suppression of EV-A71 and target of viral evasion.
Signal transduction and targeted therapy
Zheng W,Zhou Z,Rui Y,Ye R,Xia F,Guo F,Liu X,Su J,Lou M,Yu XF
Fri Feb 24 00:00:00 UTC 2023
Flavivirus prM interacts with MDA5 and MAVS to inhibit RLR antiviral signaling.
Cell & bioscience
Sui L,Zhao Y,Wang W,Chi H,Tian T,Wu P,Zhang J,Zhao Y,Wei ZK,Hou Z,Zhou G,Wang G,Wang Z,Liu Q
Fri Jan 13 00:00:00 UTC 2023
Enterovirus D68 VP3 Targets the Interferon Regulatory Factor 7 To Inhibit Type I Interferon Response.
Microbiology spectrum
Kang J,Huang M,Li J,Zhang K,Zhu C,Liu S,Zhou Z,Wang T,Wang Z
Thu Jun 15 00:00:00 UTC 2023
Hepatocyte-derived MASP1-enriched small extracellular vesicles activate HSCs to promote liver fibrosis.
Hepatology (Baltimore, Md.)
Liu X,Tan S,Liu H,Jiang J,Wang X,Li L,Wu B
Sat Apr 01 00:00:00 UTC 2023
TRIM28 represses renal cell carcinoma cell proliferation by inhibiting TFE3/KDM6A-regulated autophagy.
The Journal of biological chemistry
Song T,Lv S,Ma X,Zhao X,Fan L,Zou Q,Li N,Yan Y,Zhang W,Sun L
Mon May 01 00:00:00 UTC 2023
An evolutionarily conserved N-terminal leucine is essential for MX1 GTPase antiviral activity against different families of RNA viruses.
The Journal of biological chemistry
McKellar J,Arnaud-Arnould M,Chaloin L,Tauziet M,Arpin-André C,Pourcelot O,Blaise M,Moncorgé O,Goujon C
Sun Jan 01 00:00:00 UTC 2023
NKAP acts with HDAC3 to prevent R-loop associated genome instability.
Cell death and differentiation
Zhang X,Duan J,Li Y,Jin X,Wu C,Yang X,Lu W,Ge W
Sat Jul 01 00:00:00 UTC 2023
The E3 ligase RNF5 restricts SARS-CoV-2 replication by targeting its envelope protein for degradation.
Signal transduction and targeted therapy
Li Z,Hao P,Zhao Z,Gao W,Huan C,Li L,Chen X,Wang H,Jin N,Luo ZQ,Li C,Zhang W
Fri Feb 03 00:00:00 UTC 2023
MCU Upregulation Overactivates Mitophagy by Promoting VDAC1 Dimerization and Ubiquitination in the Hepatotoxicity of Cadmium.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Liu C,Li HJ,Duan WX,Duan Y,Yu Q,Zhang T,Sun YP,Li YY,Liu YS,Xu SC
Wed Mar 01 00:00:00 UTC 2023
RNA-binding motif 4 promotes angiogenesis in HCC by selectively activating VEGF-A expression.
Pharmacological research
Han H,Lin T,Wang Z,Song J,Fang Z,Zhang J,You X,Du Y,Ye J,Zhou G
Sun Jan 01 00:00:00 UTC 2023
RNA-binding motif 4 promotes angiogenesis in HCC by selectively activating VEGF-A expression.
Pharmacological research
Han H,Lin T,Wang Z,Song J,Fang Z,Zhang J,You X,Du Y,Ye J,Zhou G
Sun Jan 01 00:00:00 UTC 2023
OTUD1 chemosensitizes triple-negative breast cancer to doxorubicin by modulating P16 expression.
Pathology, research and practice
Zhou T,Wu Y,Qian D,Tang H,Liu X,Qiu J,Wang D,Hong W,Meng X,Zheng Q
Sat Jul 01 00:00:00 UTC 2023
OTUD1 chemosensitizes triple-negative breast cancer to doxorubicin by modulating P16 expression.
Pathology, research and practice
Zhou T,Wu Y,Qian D,Tang H,Liu X,Qiu J,Wang D,Hong W,Meng X,Zheng Q
Sat Jul 01 00:00:00 UTC 2023
Methionine restriction promotes cGAS activation and chromatin untethering through demethylation to enhance antitumor immunity.
Cancer cell
Fang L,Hao Y,Yu H,Gu X,Peng Q,Zhuo H,Li Y,Liu Z,Wang J,Chen Y,Zhang J,Tian H,Gao Y,Gao R,Teng H,Shan Z,Zhu J,Li Z,Liu Y,Zhang Y,Yu F,Lin Z,Hao Y,Ge X,Yuan J,Hu HG,Ma Y,Qin HL,Wang P
Mon Jun 12 00:00:00 UTC 2023
UL135 and UL136 Epistasis Controls Reactivation of Human Cytomegalovirus.
bioRxiv : the preprint server for biology
Moy MA,Collins-McMillen D,Crawford L,Parkins C,Zeltzer S,Caviness K,Caposio P,Goodrum F
Tue Jan 24 00:00:00 UTC 2023
Partial Truncation of the C-Terminal Domain of PTCH1 in Cancer Enhances Autophagy and Metabolic Adaptability.
Cancers
Caballero-Ruiz B,Gkotsi DS,Ollerton H,Morales-Alcala CC,Bordone R,Jenkins GML,Di Magno L,Canettieri G,Riobo-Del Galdo NA
Fri Jan 06 00:00:00 UTC 2023
Partial Truncation of the C-Terminal Domain of PTCH1 in Cancer Enhances Autophagy and Metabolic Adaptability.
Cancers
Caballero-Ruiz B,Gkotsi DS,Ollerton H,Morales-Alcala CC,Bordone R,Jenkins GML,Di Magno L,Canettieri G,Riobo-Del Galdo NA
Fri Jan 06 00:00:00 UTC 2023
Ginsenoside Rg3 increases gemcitabine sensitivity of pancreatic adenocarcinoma via reducing ZFP91 mediated TSPYL2 destabilization.
Journal of ginseng research
Pan H,Yang L,Bai H,Luo J,Deng Y
Thu Sep 01 00:00:00 UTC 2022
Ginsenoside Rg3 increases gemcitabine sensitivity of pancreatic adenocarcinoma via reducing ZFP91 mediated TSPYL2 destabilization.
Journal of ginseng research
Pan H,Yang L,Bai H,Luo J,Deng Y
Thu Sep 01 00:00:00 UTC 2022
The A-to-I editing of KPC1 promotes intrahepatic cholangiocarcinoma by attenuating proteasomal processing of NF-κB1 p105 to p50.
Journal of experimental & clinical cancer research : CR
Gao C,Zhou G,Shi J,Shi P,Jin L,Li Y,Wang X,Liao S,Yan H,Wu J,Lu Y,Zhai Y,Zhang J,Zhang H,Zhang H,Yang C,Cao P,Cheng S,Zhou G
Thu Dec 08 00:00:00 UTC 2022
The A-to-I editing of KPC1 promotes intrahepatic cholangiocarcinoma by attenuating proteasomal processing of NF-κB1 p105 to p50.
Journal of experimental & clinical cancer research : CR
Gao C,Zhou G,Shi J,Shi P,Jin L,Li Y,Wang X,Liao S,Yan H,Wu J,Lu Y,Zhai Y,Zhang J,Zhang H,Zhang H,Yang C,Cao P,Cheng S,Zhou G
Thu Dec 08 00:00:00 UTC 2022
Deubiquitination of BES1 by UBP12/UBP13 promotes brassinosteroid signaling and plant growth.
Plant communications
Park SH,Jeong JS,Zhou Y,Binte Mustafa NF,Chua NH
Mon Sep 12 00:00:00 UTC 2022
Deubiquitination of BES1 by UBP12/UBP13 promotes brassinosteroid signaling and plant growth.
Plant communications
Park SH,Jeong JS,Zhou Y,Binte Mustafa NF,Chua NH
Mon Sep 12 00:00:00 UTC 2022
Nanobody-Based Bispecific Neutralizer for Shiga Toxin-Producing E. coli.
ACS infectious diseases
Lu Z,Liu Z,Li X,Qin X,Hong H,Zhou Z,Pieters RJ,Shi J,Wu Z
Fri Feb 11 00:00:00 UTC 2022
NCAPG2 Maintains Cancer Stemness and Promotes Erlotinib Resistance in Lung Adenocarcinoma.
Cancers
Jiang S,Huang J,He H,Liu Y,Liang L,Sun X,Li Y,Cong L,Qing B,Jiang Y
Fri Sep 09 00:00:00 UTC 2022
DNAAF5 promotes hepatocellular carcinoma malignant progression by recruiting USP39 to improve PFKL protein stability.
Frontiers in oncology
Liu Y,Wu Q,Sun T,Huang J,Han G,Han H
Tue Oct 25 00:00:00 UTC 2022
Megalin Orchestrates FcRn Endocytosis and Trafficking.
Cells
Dahlke E,Anan Y,Klie LM,Hartkopf AE,Theilig F
Thu Dec 22 00:00:00 UTC 2022
Megalin Orchestrates FcRn Endocytosis and Trafficking.
Cells
Dahlke E,Anan Y,Klie LM,Hartkopf AE,Theilig F
Thu Dec 22 00:00:00 UTC 2022
Papain-like protease of SARS-CoV-2 inhibits RLR signaling in a deubiquitination-dependent and deubiquitination-independent manner.
Frontiers in immunology
Ran XH,Zhu JW,Chen YY,Ni RZ,Mu D
Tue Aug 30 00:00:00 UTC 2022
Sleeve gastrectomy improves lipid dysmetabolism by downregulating the USP20-HSPA2 axis in diet-induced obese mice.
Frontiers in endocrinology
Zhang W,Shi B,Li S,Liu Z,Li S,Dong S,Cheng Y,Zhu J,Zhang G,Zhong M
Tue Jan 17 00:00:00 UTC 2023
Sleeve gastrectomy improves lipid dysmetabolism by downregulating the USP20-HSPA2 axis in diet-induced obese mice.
Frontiers in endocrinology
Zhang W,Shi B,Li S,Liu Z,Li S,Dong S,Cheng Y,Zhu J,Zhang G,Zhong M
Tue Jan 17 00:00:00 UTC 2023
Sleeve gastrectomy improves lipid dysmetabolism by downregulating the USP20-HSPA2 axis in diet-induced obese mice.
Frontiers in endocrinology
Zhang W,Shi B,Li S,Liu Z,Li S,Dong S,Cheng Y,Zhu J,Zhang G,Zhong M
Tue Jan 17 00:00:00 UTC 2023
MST1 mediates neuronal loss and cognitive deficits: A novel therapeutic target for Alzheimer's disease.
Progress in neurobiology
Wang H,Shang Y,Wang E,Xu X,Zhang Q,Qian C,Yang Z,Wu S,Zhang T
Fri Jul 01 00:00:00 UTC 2022
TRIM67 Suppresses TNFalpha-Triggered NF-kB Activation by Competitively Binding Beta-TrCP to IkBa.
Frontiers in immunology
Fan W,Liu X,Zhang J,Qin L,Du J,Li X,Qian S,Chen H,Qian P
Mon May 02 00:00:00 UTC 2022
PBK drives PARP inhibitor resistance through the TRIM37/NFκB axis in ovarian cancer.
Experimental & molecular medicine
Ma H,Qi G,Han F,Peng J,Yuan C,Kong B
Fri Jul 01 00:00:00 UTC 2022
PBK drives PARP inhibitor resistance through the TRIM37/NFκB axis in ovarian cancer.
Experimental & molecular medicine
Ma H,Qi G,Han F,Peng J,Yuan C,Kong B
Fri Jul 01 00:00:00 UTC 2022
S-palmitoylation of PCSK9 induces sorafenib resistance in liver cancer by activating the PI3K/AKT pathway.
Cell reports
Sun Y,Zhang H,Meng J,Guo F,Ren D,Wu H,Jin X
Tue Aug 16 00:00:00 UTC 2022
Deficiency of WTAP in hepatocytes induces lipoatrophy and non-alcoholic steatohepatitis (NASH).
Nature communications
Li X,Ding K,Li X,Yuan B,Wang Y,Yao Z,Wang S,Huang H,Xu B,Xie L,Deng T,Chen XW,Chen Z
Thu Aug 04 00:00:00 UTC 2022
The risk variant rs11836367 contributes to breast cancer onset and metastasis by attenuating Wnt signaling via regulating NTN4 expression.
Science advances
Yang H,Ting X,Geng YH,Xie Y,Nierenberg JL,Huo YF,Zhou YT,Huang Y,Yu YQ,Yu XY,Li XF,Ziv E,Zhang H,Fang WG,Shen Y,Tian XX
Fri Jun 10 00:00:00 UTC 2022
The genomic stability regulator PTIP is required for proper chromosome segregation in mitosis.
Cell division
Zhang F,Wei M,Chen H,Ji L,Nie Y,Kang J
Sat Sep 24 00:00:00 UTC 2022
Stub1 maintains proteostasis of master transcription factors in embryonic stem cells.
Cell reports
Mamun MMA,Khan MR,Zhu Y,Zhang Y,Zhou S,Xu R,Bukhari I,Thorne RF,Li J,Zhang XD,Liu G,Chen S,Wu M,Song X
Tue Jun 07 00:00:00 UTC 2022
Brown adipose tissue involution associated with progressive restriction in progenitor competence.
Cell reports
Huang Z,Zhang Z,Moazzami Z,Heck R,Hu P,Nanda H,Ren K,Sun Z,Bartolomucci A,Gao Y,Chung D,Zhu W,Shen S,Ruan HB
Tue Apr 12 00:00:00 UTC 2022
Brown adipose tissue involution associated with progressive restriction in progenitor competence.
Cell reports
Huang Z,Zhang Z,Moazzami Z,Heck R,Hu P,Nanda H,Ren K,Sun Z,Bartolomucci A,Gao Y,Chung D,Zhu W,Shen S,Ruan HB
Tue Apr 12 00:00:00 UTC 2022
Msi2-mediated MiR7a-1 processing repression promotes myogenesis.
Journal of cachexia, sarcopenia and muscle
Yang W,Yang L,Wang J,Zhang Y,Li S,Yin Q,Suo J,Ma R,Ye Y,Cheng H,Li J,Hui J,Hu P
Tue Feb 01 00:00:00 UTC 2022
Non-catalytic allostery in α-TAT1 by a phospho-switch drives dynamic microtubule acetylation.
The Journal of cell biology
Deb Roy A,Gross EG,Pillai GS,Seetharaman S,Etienne-Manneville S,Inoue T
Mon Nov 07 00:00:00 UTC 2022
PML Body Component Sp100A Restricts Wild-Type Herpes Simplex Virus 1 Infection.
Journal of virology
Ma Y,Li J,Dong H,Yang Z,Zhou L,Xu P
Wed Apr 27 00:00:00 UTC 2022
UBE2O and USP7 co-regulate RECQL4 ubiquitinylation and homologous recombination-mediated DNA repair.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Huang Q,Qin D,Pei D,Vermeulen M,Zhang X
Sat Jan 01 00:00:00 UTC 2022
Actl7a deficiency in mice leads to male infertility and fertilization failure.
Biochemical and biophysical research communications
Zhou X,Liu Z,Jia W,Hou M,Zhang X
Sat Oct 01 00:00:00 UTC 2022
Actl7a deficiency in mice leads to male infertility and fertilization failure.
Biochemical and biophysical research communications
Zhou X,Liu Z,Jia W,Hou M,Zhang X
Sat Oct 01 00:00:00 UTC 2022
PPDPF Promotes the Progression and acts as an Antiapoptotic Protein in Non-Small Cell Lung Cancer.
International journal of biological sciences
Yun M,Yingzi L,Jie G,Guanxin L,Zimei Z,Zhen C,Zhi L,Yingjie N,Lunquan S,Tao C,Yuezhen D,Chengzhi Z
Mon Mar 28 00:00:00 UTC 2022
PPDPF Promotes the Progression and acts as an Antiapoptotic Protein in Non-Small Cell Lung Cancer.
International journal of biological sciences
Yun M,Yingzi L,Jie G,Guanxin L,Zimei Z,Zhen C,Zhi L,Yingjie N,Lunquan S,Tao C,Yuezhen D,Chengzhi Z
Mon Mar 28 00:00:00 UTC 2022
NRBF2 regulates the chemoresistance of small cell lung cancer by interacting with the P62 protein in the autophagy process.
iScience
Shen W,Luo P,Sun Y,Zhang W,Zhou N,Zhan H,Zhang Q,Shen J,Lin A,Cheng Q,Wang Q,Zhang J,Wang HH,Wei T
Fri Jun 17 00:00:00 UTC 2022
MICAL1 inhibits colorectal cancer cell migration and proliferation by regulating the EGR1/β-catenin signaling pathway.
Biochemical pharmacology
Gu H,Li Y,Cui X,Cao H,Hou Z,Ti Y,Liu D,Gao J,Wang Y,Wen P
Sat Jan 01 00:00:00 UTC 2022
UBE2O ubiquitinates PTRF/CAVIN1 and inhibits the secretion of exosome-related PTRF/CAVIN1.
Cell communication and signaling : CCS
Cen X,Chen Q,Wang B,Xu H,Wang X,Ling Y,Zhang X,Qin D
Mon Nov 28 00:00:00 UTC 2022
USP5 promotes breast cancer cell proliferation and metastasis by stabilizing HIF2α.
Journal of cellular physiology
Huang W,Liu X,Zhang Y,Deng M,Li G,Chen G,Yu L,Jin L,Liu T,Wang Y,Chen Y
Fri Apr 01 00:00:00 UTC 2022
Ubiquitin ligase RNF125 targets PD-L1 for ubiquitination and degradation.
Frontiers in oncology
Wei M,Mo Y,Liu J,Zhai J,Li H,Xu Y,Peng Y,Tang Z,Wei T,Yang X,Huang L,Shao X,Li J,Zhou L,Zhong H,Wei C,Xie Q,Min M,Wu F
Tue Aug 16 00:00:00 UTC 2022
Mouse Ocilrp2/Clec2i negatively regulates LPS-mediated IL-6 production by blocking Dap12-Syk interaction in macrophage.
Frontiers in immunology
Cao M,Ma L,Yan C,Wang H,Ran M,Chen Y,Wang X,Liang X,Chai L,Li X
Fri Oct 28 00:00:00 UTC 2022
Mouse Ocilrp2/Clec2i negatively regulates LPS-mediated IL-6 production by blocking Dap12-Syk interaction in macrophage.
Frontiers in immunology
Cao M,Ma L,Yan C,Wang H,Ran M,Chen Y,Wang X,Liang X,Chai L,Li X
Fri Oct 28 00:00:00 UTC 2022
The carboxy-terminal tail of GLR3.3 is essential for wound-response electrical signaling.
The New phytologist
Wu Q,Stolz S,Kumari A,Farmer EE
Thu Dec 01 00:00:00 UTC 2022
TRAF4 Promotes the Proliferation of Glioblastoma by Stabilizing SETDB1 to Activate the AKT Pathway.
International journal of molecular sciences
Gu H,Zhu S,Peng C,Wei Z,Shen Y,Yuan C,Yang H,Cui H,Yang L
Mon Sep 05 00:00:00 UTC 2022
TaFDL2-1A confers drought stress tolerance by promoting ABA biosynthesis, ABA responses, and ROS scavenging in transgenic wheat.
The Plant journal : for cell and molecular biology
Wang B,Li L,Liu M,Peng D,Wei A,Hou B,Lei Y,Li X
Tue Nov 01 00:00:00 UTC 2022
Histone methyltransferase Dot1L recruits O-GlcNAc transferase to target chromatin sites to regulate histone O-GlcNAcylation.
The Journal of biological chemistry
Xu B,Zhang C,Jiang A,Zhang X,Liang F,Wang X,Li D,Liu C,Liu X,Xia J,Li Y,Wang Y,Yang Z,Chen J,Zhou Y,Chen L,Sun H
Fri Jul 01 00:00:00 UTC 2022
METTL3 acetylation impedes cancer metastasis via fine-tuning its nuclear and cytosolic functions.
Nature communications
Li Y,He X,Lu X,Gong Z,Li Q,Zhang L,Yang R,Wu C,Huang J,Ding J,He Y,Liu W,Chen C,Cao B,Zhou D,Shi Y,Chen J,Wang C,Zhang S,Zhang J,Ye J,You H
Wed Oct 26 00:00:00 UTC 2022
METTL3 acetylation impedes cancer metastasis via fine-tuning its nuclear and cytosolic functions.
Nature communications
Li Y,He X,Lu X,Gong Z,Li Q,Zhang L,Yang R,Wu C,Huang J,Ding J,He Y,Liu W,Chen C,Cao B,Zhou D,Shi Y,Chen J,Wang C,Zhang S,Zhang J,Ye J,You H
Wed Oct 26 00:00:00 UTC 2022
Upregulation of miR-520c-3p via hepatitis B virus drives hepatocellular migration and invasion by the PTEN/AKT/NF-κB axis.
Molecular therapy. Nucleic acids
Liu Y,Wang J,Chen J,Wu S,Zeng X,Xiong Q,Guo Y,Sun J,Song F,Xu J,Yuan S,Li C,He Y,Wang M,Chen L,Shi YB,Guo M,Guo D,Sun G
Tue Sep 13 00:00:00 UTC 2022
Upregulation of miR-520c-3p via hepatitis B virus drives hepatocellular migration and invasion by the PTEN/AKT/NF-κB axis.
Molecular therapy. Nucleic acids
Liu Y,Wang J,Chen J,Wu S,Zeng X,Xiong Q,Guo Y,Sun J,Song F,Xu J,Yuan S,Li C,He Y,Wang M,Chen L,Shi YB,Guo M,Guo D,Sun G
Tue Sep 13 00:00:00 UTC 2022
Alternative splicing of HSPA12A pre-RNA by SRSF11 contributes to metastasis potential of colorectal cancer.
Clinical and translational medicine
Pan YJ,Huo FC,Kang MJ,Liu BW,Wu MD,Pei DS
Tue Nov 01 00:00:00 UTC 2022
Alternative splicing of HSPA12A pre-RNA by SRSF11 contributes to metastasis potential of colorectal cancer.
Clinical and translational medicine
Pan YJ,Huo FC,Kang MJ,Liu BW,Wu MD,Pei DS
Tue Nov 01 00:00:00 UTC 2022
A synapsin Ⅰ cleavage fragment contributes to synaptic dysfunction in Alzheimer's disease.
Aging cell
Meng L,Zou L,Xiong M,Chen J,Zhang X,Yu T,Li Y,Liu C,Chen G,Wang Z,Ye K,Zhang Z
Sun May 01 00:00:00 UTC 2022
eIF4A3 Promotes RNA Viruses' Replication by Inhibiting Innate Immune Responses.
Journal of virology
Gao Q,Jiang M,Zhao Y,Li G,Yang C,Ren C,Jin M,Chen H,Zhou H
Wed Nov 23 00:00:00 UTC 2022
Fbxo45 facilitates pancreatic carcinoma progression by targeting USP49 for ubiquitination and degradation.
Cell death & disease
Wu L,Yu K,Chen K,Zhu X,Yang Z,Wang Q,Gao J,Wang Y,Cao T,Xu H,Pan X,Wang L,Xia J,Li Y,Wang ZP,Ma J
Sat Mar 12 00:00:00 UTC 2022
AHSA1 is a promising therapeutic target for cellular proliferation and proteasome inhibitor resistance in multiple myeloma.
Journal of experimental & clinical cancer research : CR
Gu C,Wang Y,Zhang L,Qiao L,Sun S,Shao M,Tang X,Ding P,Tang C,Cao Y,Zhou Y,Guo M,Wei R,Li N,Xiao Y,Duan J,Yang Y
Thu Jan 06 00:00:00 UTC 2022
ARF GTPases activate Salmonella effector SopF to ADP-ribosylate host V-ATPase and inhibit endomembrane damage-induced autophagy.
Nature structural & molecular biology
Xu Y,Cheng S,Zeng H,Zhou P,Ma Y,Li L,Liu X,Shao F,Ding J
Sat Jan 01 00:00:00 UTC 2022
The ZFP541-KCTD19 complex is essential for pachytene progression by activating meiotic genes during mouse spermatogenesis.
Journal of genetics and genomics = Yi chuan xue bao
Li Y,Meng R,Li S,Gu B,Xu X,Zhang H,Tan X,Shao T,Wang J,Xu D,Wang F
Tue Nov 01 00:00:00 UTC 2022
A WWP2-PTEN-KLF5 signaling axis regulates odontoblast differentiation and dentinogenesis in mice.
The Journal of biological chemistry
Fu J,Zhang X,Zheng H,Yang G,Chen Z,Yuan G
Mon Aug 01 00:00:00 UTC 2022
Autophagy Protects Ocular Surface Against Overactivated Inflammation by Degrading Retinoic Acid-Induced Gene-I in Human Conjunctival Epithelial Cells.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics
Zhou J,Huang Q,Wang L,Li E,Huang W,Xiang Z
Wed Jun 01 00:00:00 UTC 2022
HPV E6/E7 promotes aerobic glycolysis in cervical cancer by regulating IGF2BP2 to stabilize m6A-MYC expression.
International journal of biological sciences
Hu C,Liu T,Han C,Xuan Y,Jiang D,Sun Y,Zhang X,Zhang W,Xu Y,Liu Y,Pan J,Wang J,Fan J,Che Y,Huang Y,Zhang J,Ding J,Yang S,Yang K
Mon Mar 21 00:00:00 UTC 2022
IQGAP1 is positively correlated with PD-L1 and regulates its expression via mediating STAT proteins phosphorylation.
International immunopharmacology
Chen Y,Mei J,Zhang P,Liu J,Chen L,Wu L,Zhang Y
Fri Jul 01 00:00:00 UTC 2022
Multiple ciliary localization signals control INPP5E ciliary targeting.
eLife
Cilleros-Rodriguez D,Martin-Morales R,Barbeito P,Deb Roy A,Loukil A,Sierra-Rodero B,Herranz G,Pampliega O,Redrejo-Rodriguez M,Goetz SC,Izquierdo M,Inoue T,Garcia-Gonzalo FR
Mon Sep 05 00:00:00 UTC 2022
Multiple ciliary localization signals control INPP5E ciliary targeting.
eLife
Cilleros-Rodriguez D,Martin-Morales R,Barbeito P,Deb Roy A,Loukil A,Sierra-Rodero B,Herranz G,Pampliega O,Redrejo-Rodriguez M,Goetz SC,Izquierdo M,Inoue T,Garcia-Gonzalo FR
Mon Sep 05 00:00:00 UTC 2022
Interactome screening of C9orf72 dipeptide repeats reveals VCP sequestration and functional impairment by polyGA.
Brain : a journal of neurology
Božič J,Motaln H,Janež AP,Markič L,Tripathi P,Yamoah A,Aronica E,Lee YB,Heilig R,Fischer R,Thompson AJ,Goswami A,Rogelj B
Mon Apr 18 00:00:00 UTC 2022
SSBP1 drives high fructose-induced glomerular podocyte ferroptosis via activating DNA-PK/p53 pathway.
Redox biology
Wu WY,Wang ZX,Li TS,Ding XQ,Liu ZH,Yang J,Fang L,Kong LD
Wed Jun 01 00:00:00 UTC 2022
Lysine demethylase KDM1A promotes cell growth via FKBP8-BCL2 axis in hepatocellular carcinoma.
The Journal of biological chemistry
Lv S,Zhao X,Zhang E,Yan Y,Ma X,Li N,Zou Q,Sun L,Song T
Thu Sep 01 00:00:00 UTC 2022
Lysine demethylase KDM1A promotes cell growth via FKBP8-BCL2 axis in hepatocellular carcinoma.
The Journal of biological chemistry
Lv S,Zhao X,Zhang E,Yan Y,Ma X,Li N,Zou Q,Sun L,Song T
Thu Sep 01 00:00:00 UTC 2022
Drebrin promotes lung adenocarcinoma cell migration through inducing integrin β1 endocytosis.
Biochemical and biophysical research communications
Yu Q,Tang F,Cao F,Tan X,Weng L,Sun L
Sat Nov 19 00:00:00 UTC 2022
A novel FBW7/NFAT1 axis regulates cancer immunity in sunitinib-resistant renal cancer by inducing PD-L1 expression.
Journal of experimental & clinical cancer research : CR
Liu W,Ren D,Xiong W,Jin X,Zhu L
Wed Jan 26 00:00:00 UTC 2022
A novel FBW7/NFAT1 axis regulates cancer immunity in sunitinib-resistant renal cancer by inducing PD-L1 expression.
Journal of experimental & clinical cancer research : CR
Liu W,Ren D,Xiong W,Jin X,Zhu L
Wed Jan 26 00:00:00 UTC 2022
Lactylation-driven METTL3-mediated RNA m6A modification promotes immunosuppression of tumor-infiltrating myeloid cells.
Molecular cell
Xiong J,He J,Zhu J,Pan J,Liao W,Ye H,Wang H,Song Y,Du Y,Cui B,Xue M,Zheng W,Kong X,Jiang K,Ding K,Lai L,Wang Q
Thu May 05 00:00:00 UTC 2022
Lactylation-driven METTL3-mediated RNA m6A modification promotes immunosuppression of tumor-infiltrating myeloid cells.
Molecular cell
Xiong J,He J,Zhu J,Pan J,Liao W,Ye H,Wang H,Song Y,Du Y,Cui B,Xue M,Zheng W,Kong X,Jiang K,Ding K,Lai L,Wang Q
Thu May 05 00:00:00 UTC 2022
Grass carp SERPINA1 inhibits GCRV infection through degrading CF2.
Frontiers in immunology
Li Y,Chen L,Huang R,Li Y,Yang C,Gui B,Li Y,Liao L,Zhu Z,Wang Y
Wed Sep 28 00:00:00 UTC 2022
Grass carp SERPINA1 inhibits GCRV infection through degrading CF2.
Frontiers in immunology
Li Y,Chen L,Huang R,Li Y,Yang C,Gui B,Li Y,Liao L,Zhu Z,Wang Y
Wed Sep 28 00:00:00 UTC 2022
C-terminal-mediated homodimerization of Expanded is critical for its ability to promote Hippo signalling in Drosophila.
FEBS letters
Wang G,Zhai C,Ji X,Wang E,Zhao S,Qian C,Yu D,Wang Y,Wu S
Fri Jul 01 00:00:00 UTC 2022
LINC00941 promotes pancreatic cancer malignancy by interacting with ANXA2 and suppressing NEDD4L-mediated degradation of ANXA2.
Cell death & disease
Wang J,He Z,Liu X,Xu J,Jiang X,Quan G,Jiang J
Thu Aug 18 00:00:00 UTC 2022
LINC00941 promotes pancreatic cancer malignancy by interacting with ANXA2 and suppressing NEDD4L-mediated degradation of ANXA2.
Cell death & disease
Wang J,He Z,Liu X,Xu J,Jiang X,Quan G,Jiang J
Thu Aug 18 00:00:00 UTC 2022
The activity of disease-causative STING variants can be suppressed by wild-type STING through heterocomplex formation.
Frontiers in cell and developmental biology
Shindo R,Kuchitsu Y,Mukai K,Taguchi T
Tue Nov 29 00:00:00 UTC 2022
Severe Acute Respiratory Syndrome Coronavirus 2 ORF8 Protein Inhibits Type I Interferon Production by Targeting HSP90B1 Signaling.
Frontiers in cellular and infection microbiology
Chen J,Lu Z,Yang X,Zhou Y,Gao J,Zhang S,Huang S,Cai J,Yu J,Zhao W,Zhang B
Fri Jun 10 00:00:00 UTC 2022
Severe Acute Respiratory Syndrome Coronavirus 2 ORF8 Protein Inhibits Type I Interferon Production by Targeting HSP90B1 Signaling.
Frontiers in cellular and infection microbiology
Chen J,Lu Z,Yang X,Zhou Y,Gao J,Zhang S,Huang S,Cai J,Yu J,Zhao W,Zhang B
Fri Jun 10 00:00:00 UTC 2022
The deubiquitinating enzyme USP20 regulates the stability of the MCL1 protein.
Biochemical and biophysical research communications
Feng J,Liu P,Li X,Zhang D,Lin H,Hou Z,Guo C,Niu Y,Dai B,Wang O,Qi M,Wang H,Zhou H
Sat Feb 19 00:00:00 UTC 2022
Inhibition of the lncRNA MIAT prevents podocyte injury and mitotic catastrophe in diabetic nephropathy.
Molecular therapy. Nucleic acids
Wang Z,Chang Y,Liu Y,Liu B,Zhen J,Li X,Lin J,Yu Q,Lv Z,Wang R
Tue Jun 14 00:00:00 UTC 2022
The E3 ubiquitin ligase MG53 inhibits hepatocellular carcinoma by targeting RAC1 signaling.
Oncogenesis
Ma X,Ma X,Zhu L,Zhao Y,Chen M,Li T,Lin Y,Ma D,Sun C,Han L
Wed Jul 20 00:00:00 UTC 2022
Rab22a cooperates with Rab5 and NS4B in classical swine fever virus entry process.
Veterinary microbiology
Wang T,Liu Y,Sun Y,Zhang L,Guo K,Zhang Y
Tue Mar 01 00:00:00 UTC 2022
Rab22a cooperates with Rab5 and NS4B in classical swine fever virus entry process.
Veterinary microbiology
Wang T,Liu Y,Sun Y,Zhang L,Guo K,Zhang Y
Tue Mar 01 00:00:00 UTC 2022
HMGB3 promotes PARP inhibitor resistance through interacting with PARP1 in ovarian cancer.
Cell death & disease
Ma H,Qi G,Han F,Lu W,Peng J,Li R,Yan S,Yuan C,Kong B
Thu Mar 24 00:00:00 UTC 2022
HMGB3 promotes PARP inhibitor resistance through interacting with PARP1 in ovarian cancer.
Cell death & disease
Ma H,Qi G,Han F,Lu W,Peng J,Li R,Yan S,Yuan C,Kong B
Thu Mar 24 00:00:00 UTC 2022
RAB7 activity is required for the regulation of mitophagy in oocyte meiosis and oocyte quality control during ovarian aging.
Autophagy
Jin X,Wang K,Wang L,Liu W,Zhang C,Qiu Y,Liu W,Zhang H,Zhang D,Yang Z,Wu T,Li J
Tue Mar 01 00:00:00 UTC 2022
African Swine Fever Virus Structural Protein p17 Inhibits cGAS-STING Signaling Pathway Through Interacting With STING.
Frontiers in immunology
Zheng W,Xia N,Zhang J,Cao Q,Jiang S,Luo J,Wang H,Chen N,Zhang Q,Meurens F,Zhu J
Tue Jul 19 00:00:00 UTC 2022
African Swine Fever Virus Structural Protein p17 Inhibits cGAS-STING Signaling Pathway Through Interacting With STING.
Frontiers in immunology
Zheng W,Xia N,Zhang J,Cao Q,Jiang S,Luo J,Wang H,Chen N,Zhang Q,Meurens F,Zhu J
Tue Jul 19 00:00:00 UTC 2022
Aurora-A/FOXO3A/SKP2 axis promotes tumor progression in clear cell renal cell carcinoma and dual-targeting Aurora-A/SKP2 shows synthetic lethality.
Cell death & disease
Li P,Chen T,Kuang P,Liu F,Li Z,Liu F,Wang Y,Zhang W,Cai X
Wed Jul 13 00:00:00 UTC 2022
MYBL1 induces transcriptional activation of ANGPT2 to promote tumor angiogenesis and confer sorafenib resistance in human hepatocellular carcinoma.
Cell death & disease
Zhu J,Wu Y,Yu Y,Li Y,Shen J,Zhang R
Sat Aug 20 00:00:00 UTC 2022
PKM2 promotes pulmonary fibrosis by stabilizing TGF-β1 receptor I and enhancing TGF-β1 signaling.
Science advances
Gao S,Li X,Jiang Q,Liang Q,Zhang F,Li S,Zhang R,Luan J,Zhu J,Gu X,Xiao T,Huang H,Chen S,Ning W,Yang G,Yang C,Zhou H
Fri Sep 23 00:00:00 UTC 2022
RNF220 is an E3 ubiquitin ligase for AMPA receptors to regulate synaptic transmission.
Science advances
Ma P,Wan LP,Li Y,He CH,Song NN,Zhao S,Wang H,Ding YQ,Mao B,Sheng N
Fri Sep 30 00:00:00 UTC 2022
E3 Ligase FBXW7 Facilitates Mycobacterium Immune Evasion by Modulating TNF-α Expression.
Frontiers in cellular and infection microbiology
Song J,Chao J,Hu X,Wen X,Ding C,Li D,Zhang D,Han S,Yu X,Yan B,Jin Z,Song Y,Gonzales J,Via LE,Zhang L,Wang D
Fri Jun 03 00:00:00 UTC 2022
OsMADS14 and NF-YB1 cooperate in the direct activation of OsAGPL2 and Waxy during starch synthesis in rice endosperm.
The New phytologist
Feng T,Wang L,Li L,Liu Y,Chong K,Theißen G,Meng Z
Fri Apr 01 00:00:00 UTC 2022
LPS/Bcl3/YAP1 signaling promotes Sox9+HNF4α+ hepatocyte-mediated liver regeneration after hepatectomy.
Cell death & disease
Shao C,Jing Y,Zhao S,Yang X,Hu Y,Meng Y,Huang Y,Ye F,Gao L,Liu W,Sheng D,Li R,Zhang X,Wei L
Mon Mar 28 00:00:00 UTC 2022
TRABID targets DDB2 for deubiquitination to promote proliferation of hepatocellular carcinoma cells.
Biochemical and biophysical research communications
Chen Y,Zhang X
Sat Oct 15 00:00:00 UTC 2022
N(6)-methyladenosine-binding protein YTHDF1 suppresses EBV replication and promotes EBV RNA decay.
EMBO reports
Xia TL,Li X,Wang X,Zhu YJ,Zhang H,Cheng W,Chen ML,Ye Y,Li Y,Zhang A,Dai DL,Zhu QY,Yuan L,Zheng J,Huang H,Chen SQ,Xiao ZW,Wang HB,Roy G,Zhong Q,Lin D,Zeng YX,Wang J,Zhao B,Gewurz BE,Chen J,Zuo Z,Zeng MS
Wed Apr 07 00:00:00 UTC 2021
A γ-adducin cleavage fragment induces neurite deficits and synaptic dysfunction in Alzheimer's disease.
Progress in neurobiology
Xiong M,Zou L,Meng L,Zhang X,Tian Y,Zhang G,Yang J,Chen G,Xiong J,Ye K,Zhang Z
Sun Aug 01 00:00:00 UTC 2021
A novel mutation in ZP3 causes empty follicle syndrome and abnormal zona pellucida formation.
Journal of assisted reproduction and genetics
Zhang D,Zhu L,Liu Z,Ren X,Yang X,Li D,Luo Y,Peng X,Zhou X,Jia W,Hou M,Li Z,Jin L,Zhang X
Fri Jan 01 00:00:00 UTC 2021
PRDX2 promotes the proliferation of colorectal cancer cells by increasing the ubiquitinated degradation of p53.
Cell death & disease
Wang W,Wei J,Zhang H,Zheng X,Zhou H,Luo Y,Yang J,Deng Q,Huang S,Fu Z
Fri Jun 11 00:00:00 UTC 2021
CHEK1 and circCHEK1_246aa evoke chromosomal instability and induce bone lesion formation in multiple myeloma.
Molecular cancer
Gu C,Wang W,Tang X,Xu T,Zhang Y,Guo M,Wei R,Wang Y,Jurczyszyn A,Janz S,Beksac M,Zhan F,Seckinger A,Hose D,Pan J,Yang Y
Sat Jun 05 00:00:00 UTC 2021
CHEK1 and circCHEK1_246aa evoke chromosomal instability and induce bone lesion formation in multiple myeloma.
Molecular cancer
Gu C,Wang W,Tang X,Xu T,Zhang Y,Guo M,Wei R,Wang Y,Jurczyszyn A,Janz S,Beksac M,Zhan F,Seckinger A,Hose D,Pan J,Yang Y
Sat Jun 05 00:00:00 UTC 2021
POST1/C12ORF49 regulates the SREBP pathway by promoting site-1 protease maturation.
Protein & cell
Xiao J,Xiong Y,Yang LT,Wang JQ,Zhou ZM,Dong LW,Shi XJ,Zhao X,Luo J,Song BL
Thu Apr 01 00:00:00 UTC 2021
TDP-43 and PINK1 mediate CHCHD10S59L mutation-induced defects in Drosophila and in vitro.
Nature communications
Baek M,Choe YJ,Bannwarth S,Kim J,Maitra S,Dorn GW,Taylor JP,Paquis-Flucklinger V,Kim NC
Fri Mar 26 00:00:00 UTC 2021
Japanese Encephalitis Virus NS2B-3 Protein Complex Promotes Cell Apoptosis and Viral Particle Release by Down-Regulating the Expression of AXL.
Virologica Sinica
Xie S,Liang Z,Yang X,Pan J,Yu D,Li T,Cao R
Wed Dec 01 00:00:00 UTC 2021
SPOP negatively regulates Toll-like receptor-induced inflammation by disrupting MyD88 self-association.
Cellular & molecular immunology
Hu YH,Wang Y,Wang F,Dong YM,Jiang WL,Wang YP,Zhong X,Ma LX
Thu Jul 01 00:00:00 UTC 2021
The methyltransferase METTL3 negatively regulates nonalcoholic steatohepatitis (NASH) progression.
Nature communications
Li X,Yuan B,Lu M,Wang Y,Ding N,Liu C,Gao M,Yao Z,Zhang S,Zhao Y,Xie L,Chen Z
Fri Dec 10 00:00:00 UTC 2021
Autophagy Induced by the N-Terminus of the Classic Swine Fever Virus Nonstructural Protein 5A Protein Promotes Viral Replication.
Frontiers in microbiology
Zhang C,Wang X,Sun J,Guo M,Zhang X,Wu Y
Tue Sep 14 00:00:00 UTC 2021
Autophagy Induced by the N-Terminus of the Classic Swine Fever Virus Nonstructural Protein 5A Protein Promotes Viral Replication.
Frontiers in microbiology
Zhang C,Wang X,Sun J,Guo M,Zhang X,Wu Y
Tue Sep 14 00:00:00 UTC 2021
SIRT6 promotes angiogenesis and hemorrhage of carotid plaque via regulating HIF-1α and reactive oxygen species.
Cell death & disease
Yang Z,Huang Y,Zhu L,Yang K,Liang K,Tan J,Yu B
Tue Jan 12 00:00:00 UTC 2021
Knockdown of TRIM32 inhibits tumor growth and increases the therapeutic sensitivity to temozolomide in glioma in a p53-dependent and -independent manner.
Biochemical and biophysical research communications
Cai Y,Gu WT,Cheng K,Jia PF,Li F,Wang M,Zhang WF,Qiu JT,Wu ZB,Zhao WG
Fri Apr 23 00:00:00 UTC 2021
miR-29b-3p Increases Radiosensitivity in Stemness Cancer Cells via Modulating Oncogenes Axis.
Frontiers in cell and developmental biology
Pan D,Du Y,Li R,Shen A,Liu X,Li C,Hu B
Tue Oct 05 00:00:00 UTC 2021
GNAI2 Promotes Proliferation and Decreases Apoptosis in Rabbit Melanocytes.
Genes
Hu S,Dai Y,Bai S,Zhao B,Wu X,Chen Y
Sun Jul 25 00:00:00 UTC 2021
Ferritinophagy is involved in the zinc oxide nanoparticles-induced ferroptosis of vascular endothelial cells.
Autophagy
Qin X,Zhang J,Wang B,Xu G,Yang X,Zou Z,Yu C
Wed Dec 01 00:00:00 UTC 2021
BUB1B and circBUB1B_544aa aggravate multiple myeloma malignancy through evoking chromosomal instability.
Signal transduction and targeted therapy
Tang X,Guo M,Ding P,Deng Z,Ke M,Yuan Y,Zhou Y,Lin Z,Li M,Gu C,Gu X,Yang Y
Thu Oct 07 00:00:00 UTC 2021
BUB1B and circBUB1B_544aa aggravate multiple myeloma malignancy through evoking chromosomal instability.
Signal transduction and targeted therapy
Tang X,Guo M,Ding P,Deng Z,Ke M,Yuan Y,Zhou Y,Lin Z,Li M,Gu C,Gu X,Yang Y
Thu Oct 07 00:00:00 UTC 2021
Inefficient quality control of ribosome stalling during APP synthesis generates CAT-tailed species that precipitate hallmarks of Alzheimer's disease.
Acta neuropathologica communications
Rimal S,Li Y,Vartak R,Geng J,Tantray I,Li S,Huh S,Vogel H,Glabe C,Grinberg LT,Spina S,Seeley WW,Guo S,Lu B
Mon Oct 18 00:00:00 UTC 2021
Deubiquitinase USP35 restrains STING-mediated interferon signaling in ovarian cancer.
Cell death and differentiation
Zhang J,Chen Y,Chen X,Zhang W,Zhao L,Weng L,Tian H,Wu Z,Tan X,Ge X,Wang P,Fang L
Fri Jan 01 00:00:00 UTC 2021
Snord116 Post-transcriptionally Increases Nhlh2 mRNA Stability: Implications for Human Prader-Willi Syndrome.
Human molecular genetics
Kocher MA,Huang FW,Le E,Good DJ
Wed Jun 09 00:00:00 UTC 2021
PTIP Inhibits Cell Invasion in Esophageal Squamous Cell Carcinoma via Modulation of EphA2 Expression.
Frontiers in oncology
Han X,Zhu Y,Shen L,Zhou Y,Pang L,Zhou W,Gu H,Han K,Yang Y,Jiang C,Xie J,Zhang C,Ding L
Sat Apr 10 00:00:00 UTC 2021
SNX27-driven membrane localisation of OTULIN antagonises linear ubiquitination and NF-κB signalling activation.
Cell & bioscience
Shi R,Shi X,Qin D,Tang S,Vermeulen M,Zhang X
Tue Jul 27 00:00:00 UTC 2021
Deubiquitinase PSMD14 promotes ovarian cancer progression by decreasing enzymatic activity of PKM2.
Molecular oncology
Sun T,Liu Z,Bi F,Yang Q
Wed Dec 01 00:00:00 UTC 2021
Deubiquitinase PSMD14 promotes ovarian cancer progression by decreasing enzymatic activity of PKM2.
Molecular oncology
Sun T,Liu Z,Bi F,Yang Q
Wed Dec 01 00:00:00 UTC 2021
Deubiquitinase PSMD14 promotes ovarian cancer progression by decreasing enzymatic activity of PKM2.
Molecular oncology
Sun T,Liu Z,Bi F,Yang Q
Wed Dec 01 00:00:00 UTC 2021
EEF1A2 interacts with HSP90AB1 to promote lung adenocarcinoma metastasis via enhancing TGF-β/SMAD signalling.
British journal of cancer
Jia L,Ge X,Du C,Chen L,Zhou Y,Xiong W,Xiang J,Li G,Xiao G,Fang L,Li Z
Mon Mar 01 00:00:00 UTC 2021
DOT1L O-GlcNAcylation promotes its protein stability and MLL-fusion leukemia cell proliferation.
Cell reports
Song T,Zou Q,Yan Y,Lv S,Li N,Zhao X,Ma X,Liu H,Tang B,Sun L
Tue Sep 21 00:00:00 UTC 2021
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Membrane (M) and Spike (S) Proteins Antagonize Host Type I Interferon Response.
Frontiers in cellular and infection microbiology
Zhang Q,Chen Z,Huang C,Sun J,Xue M,Feng T,Pan W,Wang K,Dai J
Tue Jan 04 00:00:00 UTC 2022
Long noncoding RNA GAS5 accelerates diabetic wound healing and promotes lymphangiogenesis via miR-217/Prox1 axis.
Molecular and cellular endocrinology
He ZY,Huang MT,Cui X,Zhou ST,Wu Y,Zhang PH,Zhou J
Thu Jul 15 00:00:00 UTC 2021
Loss of fragile site-associated tumor suppressor promotes antitumor immunity via macrophage polarization.
Nature communications
Zhang L,Zhang K,Zhang J,Zhu J,Xi Q,Wang H,Zhang Z,Cheng Y,Yang G,Liu H,Guo X,Zhou D,Xue Z,Li Y,Zhang Q,Da Y,Liu L,Yin Z,Yao Z,Zhang R
Wed Jul 14 00:00:00 UTC 2021
COP9 Signalosome Subunit 3 Restricts Neuroinflammatory Responses During Cerebral Ischemia/Reperfusion Injury Through Stabilizing Suppressor of Cytokine Signaling 3 Protein.
Neuropsychiatric disease and treatment
Liang E,Li X,Fu W,Zhao C,Yang B,Yang Z
Fri Apr 22 00:00:00 UTC 2022
Genomic gain of RRS1 promotes hepatocellular carcinoma through reducing the RPL11-MDM2-p53 signaling.
Science advances
Cao P,Yang A,Li P,Xia X,Han Y,Zhou G,Wang R,Yang F,Li Y,Zhang Y,Cui Y,Ji H,Lu L,He F,Zhou G
Sun Aug 01 00:00:00 UTC 2021
eIF6 promotes the malignant progression of human hepatocellular carcinoma via the mTOR signaling pathway.
Journal of translational medicine
Sun L,Liu S,Wang X,Zheng X,Chen Y,Shen H
Thu May 20 00:00:00 UTC 2021
RNA-binding protein RBM47 stabilizes IFNAR1 mRNA to potentiate host antiviral activity.
EMBO reports
Wang K,Huang C,Jiang T,Chen Z,Xue M,Zhang Q,Zhang J,Dai J
Wed Aug 04 00:00:00 UTC 2021
Targeting TRIM54/Axin1/β-Catenin Axis Prohibits Proliferation and Metastasis in Hepatocellular Carcinoma.
Frontiers in oncology
Zhu J,Wu Y,Lao S,Shen J,Yu Y,Fang C,Zhang N,Li Y,Zhang R
Tue Dec 28 00:00:00 UTC 2021
(20S) Ginsenoside Rh2 Inhibits STAT3/VEGF Signaling by Targeting Annexin A2.
International journal of molecular sciences
Wang YS,Chen C,Zhang SY,Li Y,Jin YH
Fri Aug 27 00:00:00 UTC 2021
(20S) Ginsenoside Rh2 Inhibits STAT3/VEGF Signaling by Targeting Annexin A2.
International journal of molecular sciences
Wang YS,Chen C,Zhang SY,Li Y,Jin YH
Fri Aug 27 00:00:00 UTC 2021
WIPI-1 inhibits metastasis and tumour growth via the WIPI-1-TRIM21 axis and MYC regulation in nasopharyngeal carcinoma.
Oral oncology
Zhao Y,Li WF,Li QJ,He SW,He QM,Long LF,Liu N,Ma J
Mon Nov 01 00:00:00 UTC 2021
Nuclear iASPP determines cell fate by selectively inhibiting either p53 or NF-κB.
Cell death discovery
Ge W,Wang Y,Zheng S,Zhao D,Wang X,Zhang X,Hu Y
Mon Jul 26 00:00:00 UTC 2021
CircNR3C2 promotes HRD1-mediated tumor-suppressive effect via sponging miR-513a-3p in triple-negative breast cancer.
Molecular cancer
Fan Y,Wang J,Jin W,Sun Y,Xu Y,Wang Y,Liang X,Su D
Tue Feb 02 00:00:00 UTC 2021
Integral Membrane Protein 2A Is a Negative Regulator of Canonical and Non-Canonical Hedgehog Signalling.
Cells
Morales-Alcala CC,Georgiou IC,Timmis AJ,Riobo-Del Galdo NA
Fri Aug 06 00:00:00 UTC 2021
Apolipoproteins L1-6 share key cation channel-regulating residues but have different membrane insertion and ion conductance properties.
The Journal of biological chemistry
Pant J,Giovinazzo JA,Tuka LS,Peña D,Raper J,Thomson R
Sun Aug 01 00:00:00 UTC 2021
Introduction of Modified BglBrick System in Lactococcus lactis for Straightforward Assembly of Multiple Gene Cassettes.
Frontiers in bioengineering and biotechnology
Plavec TV,Ključevšek T,Berlec A
Tue Dec 28 00:00:00 UTC 2021
EPS8 supports pancreatic cancer growth by inhibiting BMI1 mediated proteasomal degradation of ALDH7A1.
Experimental cell research
Tan M,Meng J,Sun X,Fu X,Wang R
Fri Oct 01 00:00:00 UTC 2021
Endonuclease G promotes autophagy by suppressing mTOR signaling and activating the DNA damage response.
Nature communications
Wang W,Li J,Tan J,Wang M,Yang J,Zhang ZM,Li C,Basnakian AG,Tang HW,Perrimon N,Zhou Q
Wed Jan 20 00:00:00 UTC 2021
CUL5-ASB6 Complex Promotes p62/SQSTM1 Ubiquitination and Degradation to Regulate Cell Proliferation and Autophagy.
Frontiers in cell and developmental biology
Gong L,Wang K,Wang M,Hu R,Li H,Gao D,Lin M
Fri Jun 25 00:00:00 UTC 2021
Triggering Receptor Expressed on Myeloid Cells-2 (TREM2) Interacts With Colony-Stimulating Factor 1 Receptor (CSF1R) but Is Not Necessary for CSF1/CSF1R-Mediated Microglial Survival.
Frontiers in immunology
Cheng B,Li X,Dai K,Duan S,Rong Z,Chen Y,Lü L,Liu Z,Huang X,Xu H,Zhang YW,Zheng H
Thu Sep 16 00:00:00 UTC 2021
Dinitrophenol-mediated modulation of an anti-PD-L1 VHH for Fc-dependent effector functions and prolonged serum half-life.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
Liu J,Hong H,Shi J,Xie Y,Lu Z,Liu Z,Zhou Z,Bian Z,Huang Z,Wu Z
Fri Oct 01 00:00:00 UTC 2021
Gene therapy for tuberous sclerosis complex type 2 in a mouse model by delivery of AAV9 encoding a condensed form of tuberin.
Science advances
Cheah PS,Prabhakar S,Yellen D,Beauchamp RL,Zhang X,Kasamatsu S,Bronson RT,Thiele EA,Kwiatkowski DJ,Stemmer-Rachamimov A,György B,Ling KH,Kaneki M,Tannous BA,Ramesh V,Maguire CA,Breakefield XO
Fri Jan 01 00:00:00 UTC 2021
Differential requirement of MED14/17 recruitment for activation of heat inducible genes.
The New phytologist
Ohama N,Moo TL,Chua NH
Mon Mar 01 00:00:00 UTC 2021
Targeting HLA-F suppresses the proliferation of glioma cells via a reduction in hexokinase 2-dependent glycolysis.
International journal of biological sciences
Chen X,Sun N,Li R,Sang X,Li X,Zhao J,Han J,Yang J,Ikezoe T
Thu Mar 24 00:00:00 UTC 2022
Acetyl-CoA synthetase 3 promotes bladder cancer cell growth under metabolic stress.
Oncogenesis
Zhang J,Duan H,Feng Z,Han X,Gu C
Tue May 12 00:00:00 UTC 2020
The BRCC3 regulated by Cdk5 promotes the activation of neuronal NLRP3 inflammasome in Parkinson's disease models.
Biochemical and biophysical research communications
Cheng X,Xu S,Zhang C,Qin K,Yan J,Shao X
Wed Feb 12 00:00:00 UTC 2020
NPM1 upregulates the transcription of PD-L1 and suppresses T cell activity in triple-negative breast cancer.
Nature communications
Qin G,Wang X,Ye S,Li Y,Chen M,Wang S,Qin T,Zhang C,Li Y,Long Q,Hu H,Shi D,Li J,Zhang K,Zhai Q,Tang Y,Kang T,Lan P,Xie F,Lu J,Deng W
Fri Apr 03 00:00:00 UTC 2020
miR-144 Mediates High Fat-Induced Changes of Cholesterol Metabolism via Direct Regulation of C/EBPα in the Liver and Isolated Hepatocytes of Yellow Catfish.
The Journal of nutrition
Chen G,Wu K,Zhao T,Ling S,Liu W,Luo Z
Sun Mar 01 00:00:00 UTC 2020
UCH-L1-mediated Down-regulation of Estrogen Receptor α Contributes to Insensitivity to Endocrine Therapy for Breast Cancer.
Theranostics
Chen XS,Wang KS,Guo W,Li LY,Yu P,Sun XY,Wang HY,Guan YD,Tao YG,Ding BN,Yin MZ,Ren XC,Zhang Y,Chen CS,Ye YC,Yang JM,Cheng Y
Tue Apr 13 00:00:00 UTC 2021
UCH-L1-mediated Down-regulation of Estrogen Receptor α Contributes to Insensitivity to Endocrine Therapy for Breast Cancer.
Theranostics
Chen XS,Wang KS,Guo W,Li LY,Yu P,Sun XY,Wang HY,Guan YD,Tao YG,Ding BN,Yin MZ,Ren XC,Zhang Y,Chen CS,Ye YC,Yang JM,Cheng Y
Tue Apr 13 00:00:00 UTC 2021
C19orf66 interrupts Zika virus replication by inducing lysosomal degradation of viral NS3.
PLoS neglected tropical diseases
Wu Y,Yang X,Yao Z,Dong X,Zhang D,Hu Y,Zhang S,Lin J,Chen J,An S,Ye H,Zhang S,Qiu Z,He Z,Huang M,Wei G,Zhu X
Sun Mar 01 00:00:00 UTC 2020
RBM4 regulates M1 macrophages polarization through targeting STAT1-mediated glycolysis.
International immunopharmacology
Huangfu N,Zheng W,Xu Z,Wang S,Wang Y,Cheng J,Li Z,Cheng K,Zhang S,Chen X,Zhu J
Mon Jun 01 00:00:00 UTC 2020
RBM4 regulates M1 macrophages polarization through targeting STAT1-mediated glycolysis.
International immunopharmacology
Huangfu N,Zheng W,Xu Z,Wang S,Wang Y,Cheng J,Li Z,Cheng K,Zhang S,Chen X,Zhu J
Mon Jun 01 00:00:00 UTC 2020
Identification and analysis of KLF13 variants in patients with congenital heart disease.
BMC medical genetics
Li W,Li B,Li T,Zhang E,Wang Q,Chen S,Sun K
Wed Apr 15 00:00:00 UTC 2020
Identification and analysis of KLF13 variants in patients with congenital heart disease.
BMC medical genetics
Li W,Li B,Li T,Zhang E,Wang Q,Chen S,Sun K
Wed Apr 15 00:00:00 UTC 2020
Identification and analysis of KLF13 variants in patients with congenital heart disease.
BMC medical genetics
Li W,Li B,Li T,Zhang E,Wang Q,Chen S,Sun K
Wed Apr 15 00:00:00 UTC 2020
(20S)G-Rh2 Inhibits NF-κB Regulated Epithelial-Mesenchymal Transition by Targeting Annexin A2.
Biomolecules
Wang YS,Li H,Li Y,Zhang S,Jin YH
Tue Mar 31 00:00:00 UTC 2020
(20S)G-Rh2 Inhibits NF-κB Regulated Epithelial-Mesenchymal Transition by Targeting Annexin A2.
Biomolecules
Wang YS,Li H,Li Y,Zhang S,Jin YH
Tue Mar 31 00:00:00 UTC 2020
Snail promotes prostate cancer migration by facilitating SPOP ubiquitination and degradation.
Biochemical and biophysical research communications
Lv W,Huan M,Yang W,Gao Y,Wang K,Xu S,Zhang M,Ma J,Wang X,Chen Y,Li L
Thu Aug 27 00:00:00 UTC 2020
Circular RNA hsa_circ_0004872 inhibits gastric cancer progression via the miR-224/Smad4/ADAR1 successive regulatory circuit.
Molecular cancer
Ma C,Wang X,Yang F,Zang Y,Liu J,Wang X,Xu X,Li W,Jia J,Liu Z
Tue Nov 10 00:00:00 UTC 2020
ARF6-Rac1 signaling-mediated neurite outgrowth is potentiated by the neuronal adaptor FE65 through orchestrating ARF6 and ELMO1.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Chan WWR,Li W,Chang RCC,Lau KF
Tue Dec 01 00:00:00 UTC 2020
Targeting viperin to the mitochondrion inhibits the thiolase activity of the trifunctional enzyme complex.
The Journal of biological chemistry
Dumbrepatil AB,Zegalia KA,Sajja K,Kennedy RT,Marsh ENG
Fri Feb 28 00:00:00 UTC 2020
Targeting viperin to the mitochondrion inhibits the thiolase activity of the trifunctional enzyme complex.
The Journal of biological chemistry
Dumbrepatil AB,Zegalia KA,Sajja K,Kennedy RT,Marsh ENG
Fri Feb 28 00:00:00 UTC 2020
RXRα and MRTF-A have a synergistic effect in the retinoic acid-induced neural-like differentiation of adult bone marrow-derived mesenchymal stem cells.
Cell biology international
Luo Y,Liang C,Liu Y,Liu X,Xu Y
Mon Jun 01 00:00:00 UTC 2020
Polymorphisms in Human APOBEC3H Differentially Regulate Ubiquitination and Antiviral Activity.
Viruses
Chesarino NM,Emerman M
Mon Mar 30 00:00:00 UTC 2020
The vulnerability of motor and frontal cortex-dependent behaviors in mice expressing ALS-linked mutation in TDP-43.
Neurobiology of aging
Wong P,Ho WY,Yen YC,Sanford E,Ling SC
Sat Aug 01 00:00:00 UTC 2020
The acetyltransferase Eco1 elicits cohesin dimerization during S phase.
The Journal of biological chemistry
Shi D,Zhao S,Zuo MQ,Zhang J,Hou W,Dong MQ,Cao Q,Lou H
Fri May 29 00:00:00 UTC 2020
Ubiquitination of IGF2BP3 by E3 ligase MKRN2 regulates the proliferation and migration of human neuroblastoma SHSY5Y cells.
Biochemical and biophysical research communications
Jia C,Tang H,Yang Y,Yuan S,Han T,Fang M,Huang S,Hu R,Li C,Geng W
Thu Aug 13 00:00:00 UTC 2020
LRTM1 promotes the differentiation of myoblast cells by negatively regulating the FGFR1 signaling pathway.
Experimental cell research
Li HK,Zhou Y,Ding J,Xiong L,Shi YX,He YJ,Yang D,Deng ZL,Nie M,Fei Gao Y
Sun Nov 01 00:00:00 UTC 2020
USP9X promotes the proliferation, invasion and metastasis of liver cancer cells through regulating the JAK2/STAT3 signaling.
Oncology letters
Song X,Yang W,Wu C,Han Y,Lu Y
Tue Sep 01 00:00:00 UTC 2020
Hepatitis C Virus NS2 Protein Suppresses RNA Interference in Cells.
Virologica Sinica
Zhou H,Qian Q,Shu T,Xu J,Kong J,Mu J,Qiu Y,Zhou X
Sat Aug 01 00:00:00 UTC 2020
Cancer-derived sialylated IgG promotes tumor immune escape by binding to Siglecs on effector T cells.
Cellular & molecular immunology
Wang Z,Geng Z,Shao W,Liu E,Zhang J,Tang J,Wang P,Sun X,Xiao L,Xu W,Zhang Y,Cui H,Zhang L,Yang X,Chang X,Qiu X
Sun Nov 01 00:00:00 UTC 2020
Tethering of Telomeres to the Nuclear Envelope Is Mediated by SUN1-MAJIN and Possibly Promoted by SPDYA-CDK2 During Meiosis.
Frontiers in cell and developmental biology
Wang G,Wu X,Zhou L,Gao S,Yun D,Liang A,Sun F
Tue Oct 06 00:00:00 UTC 2020
PLAGL2 and POFUT1 are regulated by an evolutionarily conserved bidirectional promoter and are collaboratively involved in colorectal cancer by maintaining stemness.
EBioMedicine
Li D,Lin C,Li N,Du Y,Yang C,Bai Y,Feng Z,Su C,Wu R,Song S,Yan P,Chen M,Jain A,Huang L,Zhang Y,Li X
Mon Jul 01 00:00:00 UTC 2019
APOBEC3G is a restriction factor of EV71 and mediator of IMB-Z antiviral activity.
Antiviral research
Wang H,Zhong M,Li Y,Li K,Wu S,Guo T,Cen S,Jiang J,Li Z,Li Y
Wed May 01 00:00:00 UTC 2019
SPSB2 inhibits hepatitis C virus replication by targeting NS5A for ubiquitination and degradation.
PloS one
Wang M,Wang Y,Liu Y,Wang H,Xin X,Li J,Hao Y,Han L,Yu F,Zheng C,Shen C
Mon Mar 02 00:00:00 UTC 2020
Inhibition of tankyrase by a novel small molecule significantly attenuates prostate cancer cell proliferation.
Cancer letters
Cheng H,Li X,Wang C,Chen Y,Li S,Tan J,Tan B,He Y
Thu Feb 28 00:00:00 UTC 2019
Vibrio parahaemolyticus flagellin induces cytokines expression via toll-like receptor 5 pathway in orange-spotted grouper, Epinephelus coioides.
Fish & shellfish immunology
He L,Liang Y,Yu X,Peng W,He J,Fu L,Lin H,Zhang Y,Lu D
Mon Apr 01 00:00:00 UTC 2019
Novel interactions between ERα-36 and STAT3 mediate breast cancer cell migration.
Cell communication and signaling : CCS
Xiang Y,Li JP,Guo W,Wang DQ,Yao A,Zhang HM,Huang F,Li HH,Dai ZT,Zhang ZJ,Li H,Tan Y,Chen K,Bao LY,Liao XH
Tue Aug 13 00:00:00 UTC 2019
FGF15 Activates Hippo Signaling to Suppress Bile Acid Metabolism and Liver Tumorigenesis.
Developmental cell
Ji S,Liu Q,Zhang S,Chen Q,Wang C,Zhang W,Xiao C,Li Y,Nian C,Li J,Li J,Geng J,Hong L,Xie C,He Y,Chen X,Li X,Yin ZY,You H,Lin KH,Wu Q,Yu C,Johnson RL,Wang L,Chen L,Wang F,Zhou D
Mon Feb 25 00:00:00 UTC 2019
Identification and Functional Characterization of a New Splicing Variant of EZH2 in the Central Nervous System.
International journal of biological sciences
Li D,Wang HL,Huang X,Gu X,Xue W,Xu Y
Mon Jan 06 00:00:00 UTC 2020
Identification and Functional Characterization of a New Splicing Variant of EZH2 in the Central Nervous System.
International journal of biological sciences
Li D,Wang HL,Huang X,Gu X,Xue W,Xu Y
Mon Jan 06 00:00:00 UTC 2020
A Multidimensional Characterization of E3 Ubiquitin Ligase and Substrate Interaction Network.
iScience
Chen D,Liu X,Xia T,Tekcham DS,Wang W,Chen H,Li T,Lu C,Ning Z,Liu X,Liu J,Qi H,He H,Piao HL
Fri Jun 28 00:00:00 UTC 2019
Cathepsin D enhances breast cancer invasion and metastasis through promoting hepsin ubiquitin-proteasome degradation.
Cancer letters
Zhang C,Zhang M,Song S
Sat Dec 01 00:00:00 UTC 2018
Cathepsin D enhances breast cancer invasion and metastasis through promoting hepsin ubiquitin-proteasome degradation.
Cancer letters
Zhang C,Zhang M,Song S
Sat Dec 01 00:00:00 UTC 2018
Extracellular ATP Acts on Jasmonate Signaling to Reinforce Plant Defense.
Plant physiology
Tripathi D,Zhang T,Koo AJ,Stacey G,Tanaka K
Mon Jan 01 00:00:00 UTC 2018
Extracellular ATP Acts on Jasmonate Signaling to Reinforce Plant Defense.
Plant physiology
Tripathi D,Zhang T,Koo AJ,Stacey G,Tanaka K
Mon Jan 01 00:00:00 UTC 2018
Identification of a Novel Hemizygous SQSTM1 Nonsense Mutation in Atypical Behavioral Variant Frontotemporal Dementia.
Frontiers in aging neuroscience
Sun L,Rong Z,Li W,Zheng H,Xiao S,Li X
Wed Sep 30 00:00:00 UTC 2020
Identification of a Novel Hemizygous SQSTM1 Nonsense Mutation in Atypical Behavioral Variant Frontotemporal Dementia.
Frontiers in aging neuroscience
Sun L,Rong Z,Li W,Zheng H,Xiao S,Li X
Wed Sep 30 00:00:00 UTC 2020
Gli2 modulates cell cycle re-entry through autophagy-mediated regulation of the length of primary cilia.
Journal of cell science
Hsiao CJ,Chang CH,Ibrahim RB,Lin IH,Wang CH,Wang WJ,Tsai JW
Mon Dec 17 00:00:00 UTC 2018
Gli2 modulates cell cycle re-entry through autophagy-mediated regulation of the length of primary cilia.
Journal of cell science
Hsiao CJ,Chang CH,Ibrahim RB,Lin IH,Wang CH,Wang WJ,Tsai JW
Mon Dec 17 00:00:00 UTC 2018
Ephrin receptor A2 is an epithelial cell receptor for Epstein-Barr virus entry.
Nature microbiology
Zhang H,Li Y,Wang HB,Zhang A,Chen ML,Fang ZX,Dong XD,Li SB,Du Y,Xiong D,He JY,Li MZ,Liu YM,Zhou AJ,Zhong Q,Zeng YX,Kieff E,Zhang Z,Gewurz BE,Zhao B,Zeng MS
Thu Feb 01 00:00:00 UTC 2018
Ephrin receptor A2 is an epithelial cell receptor for Epstein-Barr virus entry.
Nature microbiology
Zhang H,Li Y,Wang HB,Zhang A,Chen ML,Fang ZX,Dong XD,Li SB,Du Y,Xiong D,He JY,Li MZ,Liu YM,Zhou AJ,Zhong Q,Zeng YX,Kieff E,Zhang Z,Gewurz BE,Zhao B,Zeng MS
Thu Feb 01 00:00:00 UTC 2018
PHB2 interacts with LC3 and SQSTM1 is required for bile acids-induced mitophagy in cholestatic liver.
Cell death & disease
Xiao Y,Zhou Y,Lu Y,Zhou K,Cai W
Wed Feb 07 00:00:00 UTC 2018
PHB2 interacts with LC3 and SQSTM1 is required for bile acids-induced mitophagy in cholestatic liver.
Cell death & disease
Xiao Y,Zhou Y,Lu Y,Zhou K,Cai W
Wed Feb 07 00:00:00 UTC 2018
Structural basis of SALM5-induced PTPδ dimerization for synaptic differentiation.
Nature communications
Lin Z,Liu J,Ding H,Xu F,Liu H
Thu Jan 18 00:00:00 UTC 2018
Structural basis of SALM5-induced PTPδ dimerization for synaptic differentiation.
Nature communications
Lin Z,Liu J,Ding H,Xu F,Liu H
Thu Jan 18 00:00:00 UTC 2018
Blocking the Thiol at Cysteine-322 Destabilizes Tau Protein and Prevents Its Oligomer Formation.
ACS chemical neuroscience
Chen H,Liu S,Li S,Chen J,Ni J,Liu Q
Wed Jul 18 00:00:00 UTC 2018
CNPY2 is a key initiator of the PERK-CHOP pathway of the unfolded protein response.
Nature structural & molecular biology
Hong F,Liu B,Wu BX,Morreall J,Roth B,Davies C,Sun S,Diehl JA,Li Z
Sun Oct 01 00:00:00 UTC 2017
CNPY2 is a key initiator of the PERK-CHOP pathway of the unfolded protein response.
Nature structural & molecular biology
Hong F,Liu B,Wu BX,Morreall J,Roth B,Davies C,Sun S,Diehl JA,Li Z
Sun Oct 01 00:00:00 UTC 2017
Accumulation of undegraded autophagosomes by expression of dominant-negative STX17 (syntaxin 17) mutants.
Autophagy
Uematsu M,Nishimura T,Sakamaki Y,Yamamoto H,Mizushima N
Thu Aug 03 00:00:00 UTC 2017
Accumulation of undegraded autophagosomes by expression of dominant-negative STX17 (syntaxin 17) mutants.
Autophagy
Uematsu M,Nishimura T,Sakamaki Y,Yamamoto H,Mizushima N
Thu Aug 03 00:00:00 UTC 2017
USP25 regulates Wnt signaling by controlling the stability of tankyrases.
Genes & development
Xu D,Liu J,Fu T,Shan B,Qian L,Pan L,Yuan J
Mon May 15 00:00:00 UTC 2017
USP25 regulates Wnt signaling by controlling the stability of tankyrases.
Genes & development
Xu D,Liu J,Fu T,Shan B,Qian L,Pan L,Yuan J
Mon May 15 00:00:00 UTC 2017
The Structure of the ZMYND8/Drebrin Complex Suggests a Cytoplasmic Sequestering Mechanism of ZMYND8 by Drebrin.
Structure (London, England : 1993)
Yao N,Li J,Liu H,Wan J,Liu W,Zhang M
Tue Nov 07 00:00:00 UTC 2017
The Structure of the ZMYND8/Drebrin Complex Suggests a Cytoplasmic Sequestering Mechanism of ZMYND8 by Drebrin.
Structure (London, England : 1993)
Yao N,Li J,Liu H,Wan J,Liu W,Zhang M
Tue Nov 07 00:00:00 UTC 2017
Fbw7 regulates apoptosis in activated B-cell like diffuse large B-cell lymphoma by targeting Stat3 for ubiquitylation and degradation.
Journal of experimental & clinical cancer research : CR
Yao S,Xu F,Chen Y,Ge Y,Zhang F,Huang H,Li L,Lin D,Luo X,Xu J,Luo D,Zhu X,Liu Y
Tue Jan 10 00:00:00 UTC 2017
Fbw7 regulates apoptosis in activated B-cell like diffuse large B-cell lymphoma by targeting Stat3 for ubiquitylation and degradation.
Journal of experimental & clinical cancer research : CR
Yao S,Xu F,Chen Y,Ge Y,Zhang F,Huang H,Li L,Lin D,Luo X,Xu J,Luo D,Zhu X,Liu Y
Tue Jan 10 00:00:00 UTC 2017
USP14 regulates autophagy by suppressing K63 ubiquitination of Beclin 1.
Genes & development
Xu D,Shan B,Sun H,Xiao J,Zhu K,Xie X,Li X,Liang W,Lu X,Qian L,Yuan J
Mon Aug 01 00:00:00 UTC 2016
CD36 regulates lipopolysaccharide-induced signaling pathways and mediates the internalization of Escherichia coli in cooperation with TLR4 in goat mammary gland epithelial cells.
Scientific reports
Cao D,Luo J,Chen D,Xu H,Shi H,Jing X,Zang W
Tue Mar 15 00:00:00 UTC 2016
CD36 regulates lipopolysaccharide-induced signaling pathways and mediates the internalization of Escherichia coli in cooperation with TLR4 in goat mammary gland epithelial cells.
Scientific reports
Cao D,Luo J,Chen D,Xu H,Shi H,Jing X,Zang W
Tue Mar 15 00:00:00 UTC 2016
Modification of BECN1 by ISG15 plays a crucial role in autophagy regulation by type I IFN/interferon.
Autophagy
Xu D,Zhang T,Xiao J,Zhu K,Wei R,Wu Z,Meng H,Li Y,Yuan J
Fri Apr 03 00:00:00 UTC 2015
Modification of BECN1 by ISG15 plays a crucial role in autophagy regulation by type I IFN/interferon.
Autophagy
Xu D,Zhang T,Xiao J,Zhu K,Wei R,Wu Z,Meng H,Li Y,Yuan J
Fri Apr 03 00:00:00 UTC 2015
Mixed Lineage Leukemia 5 (MLL5) Protein Stability Is Cooperatively Regulated by O-GlcNac Transferase (OGT) and Ubiquitin Specific Protease 7 (USP7).
PloS one
Ding X,Jiang W,Zhou P,Liu L,Wan X,Yuan X,Wang X,Chen M,Chen J,Yang J,Kong C,Li B,Peng C,Wong CC,Hou F,Zhang Y
Wed Jul 06 00:00:00 UTC 2016
Mixed Lineage Leukemia 5 (MLL5) Protein Stability Is Cooperatively Regulated by O-GlcNac Transferase (OGT) and Ubiquitin Specific Protease 7 (USP7).
PloS one
Ding X,Jiang W,Zhou P,Liu L,Wan X,Yuan X,Wang X,Chen M,Chen J,Yang J,Kong C,Li B,Peng C,Wong CC,Hou F,Zhang Y
Wed Jul 06 00:00:00 UTC 2016
Phosphorylation and activation of ubiquitin-specific protease-14 by Akt regulates the ubiquitin-proteasome system.
eLife
Xu D,Shan B,Lee BH,Zhu K,Zhang T,Sun H,Liu M,Shi L,Liang W,Qian L,Xiao J,Wang L,Pan L,Finley D,Yuan J
Mon Nov 02 00:00:00 UTC 2015
Phosphorylation and activation of ubiquitin-specific protease-14 by Akt regulates the ubiquitin-proteasome system.
eLife
Xu D,Shan B,Lee BH,Zhu K,Zhang T,Sun H,Liu M,Shi L,Liang W,Qian L,Xiao J,Wang L,Pan L,Finley D,Yuan J
Mon Nov 02 00:00:00 UTC 2015
NOS1AP O-GlcNAc Modification Involved in Neuron Apoptosis Induced by Excitotoxicity.
International journal of molecular sciences
Zhu L,Tao T,Zhang D,Liu X,Ke K,Shen A
Tue Jul 21 00:00:00 UTC 2015
AGEs-RAGE system down-regulates Sirt1 through the ubiquitin-proteasome pathway to promote FN and TGF-β1 expression in male rat glomerular mesangial cells.
Endocrinology
Huang KP,Chen C,Hao J,Huang JY,Liu PQ,Huang HQ
Thu Jan 01 00:00:00 UTC 2015
AGEs-RAGE system down-regulates Sirt1 through the ubiquitin-proteasome pathway to promote FN and TGF-β1 expression in male rat glomerular mesangial cells.
Endocrinology
Huang KP,Chen C,Hao J,Huang JY,Liu PQ,Huang HQ
Thu Jan 01 00:00:00 UTC 2015
Signal peptidase complex subunit 1 participates in the assembly of hepatitis C virus through an interaction with E2 and NS2.
PLoS pathogens
Suzuki R,Matsuda M,Watashi K,Aizaki H,Matsuura Y,Wakita T,Suzuki T
Mon Mar 17 00:00:00 UTC 2014
