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Product Details
PA5-84393
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human MYCBP2. Recombinant protein control fragment (Product #RP-108434).
Conjugate
Form
Liquid
Concentration
0.10 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2791545
Product Specific Information
Immunogen sequence: CYHPAKPFQS QLPSVKEGIS EDLPVKMPCL YLQTLARHHH ENFVGYQDDN LFQDEMRYLR STSVPAPYIS VTPDASPNVF EEPESNMKSM PPSL
Target Information
This gene encodes an E3 ubiquitin-protein ligase and member of the PHR (Phr1/MYCBP2, highwire and RPM-1) family of proteins. The encoded protein plays a role in axon guidance and synapse formation in the developing nervous system. In mammalian cells, this protein regulates the cAMP and mTOR signaling pathways, and may additionally regulate autophagy. Reduced expression of this gene has been observed in acute lymphoblastic leukemia patients and a mutation in this gene has been identified in patients with a rare inherited vision defect.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: E3 ubiquitin-protein ligase MYCBP2; Highwire; Myc-binding protein 2; pam/highwire/rpm-1 protein; probable E3 ubiquitin-protein ligase MYCBP2; Protein associated with Myc
Gene Aliases: KIAA0916; Myc-bp2; MYCBP2; PAM; Phr
UniProt ID: (Human) O75592
Entrez Gene ID: (Human) 23077
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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