Proteintech

MYH14 Polyclonal Antibody

MYH14 Antibody in Immunocytochemistry (ICC/IF)

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MYH14 Antibody (20716-1-AP) in ICC/IF

Immunofluorescent analysis of Hela cells, using MYH14 antibody 20716-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IGG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).

MYH14 Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

20716-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:3,000

View 4 publications 4 publications

Immunohistochemistry (IHC)

Assay-dependent

View 1 publication 1 publication

Immunocytochemistry (ICC/IF)

1:10-1:100

View 7 publications 7 publications

Flow Cytometry (Flow)

Assay-dependent

Immunoprecipitation (IP)

0.5-4.0 µg

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Peptide

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.25 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

The antibody is specific to MYH14.

Target Information

Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Cingulin and paracingulin tether myosins-2 to junctions to mechanoregulate the plasma membrane.

The Journal of cell biology

Rouaud F,Huang W,Flinois A,Jain K,Vasileva E,Di Mattia T,Mauperin M,Parry DAD,Dugina V,Chaponnier C,Méan I,Montessuit S,Mutero-Maeda A,Yan J,Citi S

Mon Jul 03 00:00:00 UTC 2023

Cellular shape reinforces niche to stem cell signaling in the small intestine.

Science advances

Pentinmikko N,Lozano R,Scharaw S,Andersson S,Englund JI,Castillo-Azofeifa D,Gallagher A,Broberg M,Song KY,Sola Carvajal A,Speidel AT,Sundstrom M,Allbritton N,Stevens MM,Klein OD,Teixeira A,Katajisto P

Fri Oct 14 00:00:00 UTC 2022

Mass Spectrometric Profiling of Extraocular Muscle and Proteomic Adaptations in the mdx-4cv Model of Duchenne Muscular Dystrophy.

Life (Basel, Switzerland)

Gargan S,Dowling P,Zweyer M,Reimann J,Henry M,Meleady P,Swandulla D,Ohlendieck K

Tue Jun 22 00:00:00 UTC 2021

Mass Spectrometric Profiling of Extraocular Muscle and Proteomic Adaptations in the mdx-4cv Model of Duchenne Muscular Dystrophy.

Life (Basel, Switzerland)

Gargan S,Dowling P,Zweyer M,Reimann J,Henry M,Meleady P,Swandulla D,Ohlendieck K

Tue Jun 22 00:00:00 UTC 2021

Phosphorylation of MYL12 by Myosin Light Chain Kinase Regulates Cellular Shape Changes in Cochlear Hair Cells.

Journal of the Association for Research in Otolaryngology : JARO

Oya R,Tsukamoto O,Sato T,Kato H,Matsuoka K,Oshima K,Kamakura T,Ohta Y,Imai T,Takashima S,Inohara H

Thu Jul 01 00:00:00 UTC 2021

Promoting the activation of T cells with glycopolymer-modified dendritic cells by enhancing cell interactions.

Science advances

Yu L,Feng R,Zhu L,Hao Q,Chu J,Gu Y,Luo Y,Zhang Z,Chen G,Chen H

Sun Nov 01 00:00:00 UTC 2020

Nonmuscle myosin-2 contractility-dependent actin turnover limits the length of epithelial microvilli.

Molecular biology of the cell

Chinowsky CR,Pinette JA,Meenderink LM,Lau KS,Tyska MJ

Tue Dec 01 00:00:00 UTC 2020

Therapeutic Effects of Human Urine-Derived Stem Cells in a Rat Model of Cisplatin-Induced Acute Kidney Injury In Vivo and In Vitro.

Stem cells international

Sun B,Luo X,Yang C,Liu P,Yang Y,Dong X,Yang Z,Xu J,Zhang Y,Li L

Thu May 13 00:00:00 UTC 2021

Angiotensin II-mediated MYH9 downregulation causes structural and functional podocyte injury in diabetic kidney disease.

Scientific reports

Kang JS,Lee SJ,Lee JH,Kim JH,Son SS,Cha SK,Lee ES,Chung CH,Lee EY

Wed May 22 00:00:00 UTC 2019

Angiotensin II-mediated MYH9 downregulation causes structural and functional podocyte injury in diabetic kidney disease.

Scientific reports

Kang JS,Lee SJ,Lee JH,Kim JH,Son SS,Cha SK,Lee ES,Chung CH,Lee EY

Wed May 22 00:00:00 UTC 2019

Mutations of MYH14 are associated to anorectal malformations with recto-perineal fistulas in a small subset of Chinese population.

Clinical genetics

Zhu Z,Peng L,Chen G,Jiang W,Shen Z,Du C,Zang R,Su Y,Xie H,Li H,Xia Y,Tang W

Wed Nov 01 00:00:00 UTC 2017

Mutations of MYH14 are associated to anorectal malformations with recto-perineal fistulas in a small subset of Chinese population.

Clinical genetics

Zhu Z,Peng L,Chen G,Jiang W,Shen Z,Du C,Zang R,Su Y,Xie H,Li H,Xia Y,Tang W

Wed Nov 01 00:00:00 UTC 2017

Tanshinone IIA attenuates interleukin-17A-induced systemic sclerosis patient-derived dermal vascular smooth muscle cell activation via inhibition of the extracellular signal-regulated kinase signaling pathway.

Clinics (Sao Paulo, Brazil)

Liu M,Yang J,Li M

Wed Apr 01 00:00:00 UTC 2015

Clinics (Sao Paulo, Brazil)

Liu M,Yang J,Li M

Wed Apr 01 00:00:00 UTC 2015

Bioinformatics

Protein Aliases: MYH14 variant protein; Myosin heavy chain 14; Myosin heavy chain, non-muscle IIc; myosin, heavy chain 14; myosin, heavy polypeptide 14; Myosin-14; NMHC II-C; Non-muscle myosin heavy chain IIc; nonmuscle myosin heavy chain; nonmuscle myosin heavy chain II-C

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Gene Aliases: 2400004E04Rik; DFNA4; DFNA4A; FP17425; II-C; KIAA2034; MHC16; MYH14; MYH17; myosin; NHMCII; NMHC II-C; NMHC-II-C; PNMHH

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UniProt ID: (Human) Q7Z406, (Mouse) Q6URW6

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Entrez Gene ID: (Human) 79784, (Mouse) 71960, (Rat) 308572

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Function(s)

microfilament motor activity calmodulin binding ATP binding actin-dependent ATPase activity actin filament binding nucleotide binding motor activity actin binding molecular_function

Process(es)

skeletal muscle contraction skeletal muscle tissue development sensory perception of sound regulation of cell shape neuronal action potential actin filament-based movement actomyosin structure organization mitochondrion morphogenesis vocalization behavior metabolic process biological_process skeletal muscle atrophy

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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MYH14 Polyclonal Antibody

MYH14 Antibody (20716-1-AP) in ICC/IF

Product Details

20716-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunocytochemistry (ICC/IF)

Flow Cytometry (Flow)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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